E3Docker 2.0

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[3H]rosiglitazone

E3L001188

Internal ID: BDB001188

Activity data available Local docking-ready structure

Dock with P37231 Dock with Q07869

Structure

/e3_file/ligand_db/generated/BDB001188/BDB001188.sdf

Basic Properties

Compound ID

E3L001188

Internal ID

BDB001188

Molecular formula

C18H19N3O3S

Molecular weight

357.435000

Exact mass

357.114712

XLogP

2.6430

TPSA

78.4500

HBA / HBD

6 / 2

Rotatable bonds

Heavy atoms / rings

25 / 3

Activity summary

EC50 unknown 2.40000000 nM
100 activity record(s) imported

InChIKey

FLDPBMANMDLQTH-UHFFFAOYSA-N

SMILES

CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1

Aliases

BDBM28681 (preferred) [3H]rosiglitazone (source_name) BDBM28681 (source_id)

E3 Relation

E3 UniProt	Gene / protein	Relation type	Ligand role	Direct	Functional	Docking	Source	Evidence
P37231	PPARG;NR1C3 Peroxisome proliferator-activated receptor gamma	reported_binder	bindingdb_reported	Yes	No	low	BindingDB:BDBM28681	medium ; target=Peroxisome proliferator-activated receptor gamma
Q07869	PPARA;NR1C1;PPAR Peroxisome proliferator-activated receptor alpha	reported_binder	bindingdb_reported	Yes	No	low	BindingDB:BDBM28681	medium ; target=Peroxisome proliferator-activated receptor alpha

Sources and Literature

Source	Source ID	Source URL	Download URL	DOI / PMID
BindingDB	BDBM28681	Open	-	10.1074/jbc.M702316200; 10.1016/s0960-894x(01)00649-7; 10.1016/s0960-894x(03)00702-9; 10.1016/s0960-894x(02)01029-6; 10.1021/jm9804127; 10.1021/jm030631e; 10.1016/j.bmcl.2005.07.049; 10.1016/j.bmcl.2006.08.110; 10.1016/j.bmcl.2006.08.105; 10.1016/j.bmcl.2008.01.067; 10.1016/S0960-894X(97)10017-8; 10.1021/jm201306q; 10.1016/j.bmc.2012.11.058; 10.1016/j.bmc.2009.09.001; 10.1016/s0960-894x(98)00664-7; 10.1021/jm0155188; 10.1016/s0960-894x(03)00115-x; 10.1021/jm021027r; 10.1016/s0960-894x(03)00257-9; 10.1016/s0960-894x(03)00505-5; 10.1021/jm030621d; 10.1016/j.bmcl.2004.10.042; 10.1021/jm0496436; 10.1021/jm048993p; 10.1016/j.bmcl.2005.03.092; 10.1016/j.bmcl.2005.08.002; 10.1021/jm0506930; 10.1021/jm0510373; 10.1016/j.bmcl.2006.08.003; 10.1021/jm060617c; 10.1016/j.bmcl.2006.09.011; 10.1016/j.bmcl.2006.11.029; 10.1016/j.bmcl.2007.01.060; 10.1016/j.bmcl.2007.10.047; 10.1016/j.bmcl.2009.03.036; 10.1021/jm900097m; 10.1021/jm900367w; 10.1021/jm900326c; 10.1016/j.bmc.2010.09.068; 10.1016/j.ejmech. PMID: 17403688; 11720854; 12951090; 12617924; 9836620; 15293980; 16137885; 16973358; 16979341; 18255290; 22081932; 23294830; 19783444; 9934490; 11405642; 12657263; 12672231; 12729668; 12873517; 15163205; 15582409; 15771468; 15801817; 15863293; 16153845; 16366601; 16451087; 16919947; 16970391; 17005394; 17129725; 17292606; 18029178; 19349176; 19507861; 19530681; 19719236; 21030263; 21482446; 17005393; 18291645; 19879669; 17010604; 23286787; 10691680; 11831892; 12482434; 14584939; 14695833; 15177462; 16107150; 16854085; 17034149; 17343371; 17379517; 17507225; 17553681; 17624777; 18329751; 18625559; 18771917; 19275963; 19775169; 19807106; 21112784; 21515063; 21450468; 21873070; 22051054; 22197396; 22070604; 22225641; 10714503; 16821769; 17560785; 18029176; 18826205; 19574056; 20138762; 20219371; 20299214; 20527969; 21128600; 22727448; 22582973; 22934537; 23186307; 20444603; 23171045; 23265844; 15713415; 18835719
PubChem	CID53805115	Open	-

Structure Files

Kind	Format	Status	Docking use	File / link	Preparation note
canonical_2d	SMILES	raw	Docking-ready	CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1	keep_bindingdb_unique
generated_3d	SDF	prepared	Docking-ready	public/e3_file/ligand_db/generated/BDB001188/BDB001188.sdf	Generated from canonical SMILES
generated_3d	MOL2	prepared	Docking-ready	public/e3_file/ligand_db/generated/BDB001188/BDB001188.mol2	Generated from canonical SMILES
docking_ready	PDBQT	prepared	Docking-ready	public/e3_file/ligand_db/generated/BDB001188/BDB001188.pdbqt	Generated from canonical SMILES
image	PNG	prepared	Reference	public/e3_file/ligand_db/generated/BDB001188/BDB001188.png	Generated from canonical SMILES
image	SVG	prepared	Reference	public/e3_file/ligand_db/generated/BDB001188/BDB001188.svg	Generated from canonical SMILES

Activity

Target	Source	Assay	Result	Potency	Literature	Records
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>15000 nM	Low	DOI: 10.1021/jm900326c PMID: 19719236	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>50000 nM	Low	DOI: 10.1016/s0960-894x(03)00505-5 PMID: 12873517	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>10000 nM	Low	DOI: 10.1021/jm021027r PMID: 12672231	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>15000 nM	Low	DOI: 10.1016/j.bmcl.2008.01.126 PMID: 18291645	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>50000 nM	Low	DOI: 10.1016/s0960-894x(03)00257-9 PMID: 12729668	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2004.10.042 PMID: 15582409	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>100000 nM	Low	DOI: 10.1021/jm0496436 PMID: 15771468	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>50000 nM	Low	DOI: 10.1021/jm900367w PMID: 19530681	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	15000 nM	Low	DOI: 10.1021/jm030621d PMID: 15163205	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2006.09.028 PMID: 17005393	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2009.03.036 PMID: 19349176	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>5 nM	Uncertain	DOI: 10.1016/s0960-894x(03)00115-x PMID: 12657263	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>50000 nM	Low	DOI: 10.1021/jm900097m PMID: 19507861	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>50000 nM	Low	DOI: 10.1021/jm048993p PMID: 15801817	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2007.10.047 PMID: 18029178	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2006.09.011 PMID: 17005394	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>10000 nM	Low	DOI: 10.1021/jm0510373 PMID: 16451087	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	IC50	>10000 nM	Low	DOI: 10.1021/jm0155188 PMID: 11405642	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	3460 nM	Low	DOI: 10.1021/jm8003416 PMID: 18826205	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2007.05.051 PMID: 17553681	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	200 nM	Moderate	DOI: 10.1016/j.bmcl.2004.12.084 PMID: 15713415	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	3000 nM	Low	DOI: 10.1016/j.bmcl.2006.08.110 PMID: 16973358	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2007.05.079 PMID: 17560785	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmc.2011.03.053 PMID: 21515063	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>3000 nM	Low	DOI: 10.1021/jm900367w PMID: 19530681	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1021/jm048993p PMID: 15801817	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	39 nM	High	DOI: 10.1016/j.bmc.2008.09.045 PMID: 18835719	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2010.11.030 PMID: 21112784	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>3000 nM	Low	DOI: 10.1016/s0960-894x(03)00257-9 PMID: 12729668	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	4100 nM	Low	DOI: 10.1016/j.bmcl.2007.03.015 PMID: 17379517	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	4100 nM	Low	DOI: 10.1021/jm010964g PMID: 11831892	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2009.02.072 PMID: 19275963	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	4 nM	Very high	DOI: 10.1016/j.bmcl.2008.01.067 PMID: 18255290	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2006.08.105 PMID: 16979341	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>32000 nM	Low	DOI: 10.1021/jm0496436 PMID: 15771468	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	4100 nM	Low	DOI: 10.1021/jm0309046 PMID: 14584939	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>12000 nM	Low	DOI: 10.1016/j.bmc.2009.09.001 PMID: 19783444	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2010.01.089 PMID: 20138762	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2006.08.110 PMID: 16973358	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>1000 nM	Moderate	DOI: 10.1016/j.bmc.2011.10.020 PMID: 22051054	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2009.03.036 PMID: 19349176	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1021/jm061202u PMID: 17343371	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>5000 nM	Low	DOI: 10.1016/j.bmcl.2008.01.126 PMID: 18291645	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	4100 nM	Low	DOI: 10.1016/s0960-894x(02)00881-8 PMID: 12482434	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	140 nM	Moderate	DOI: 10.1016/j.bmcl.2004.04.053 PMID: 15177462	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>3000 nM	Low	DOI: 10.1016/s0960-894x(03)00505-5 PMID: 12873517	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	3460 nM	Low	DOI: 10.1016/j.bmcl.2007.04.057 PMID: 17507225	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	>10000 nM	Low	DOI: 10.1016/j.bmcl.2005.07.049 PMID: 16137885	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	10000 nM	Low	DOI: 10.1016/j.bmcl.2008.01.067 PMID: 18255290	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	3460 nM	Low	DOI: 10.1016/j.bmcl.2008.08.020 PMID: 18771917	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	10580 nM	Low	DOI: 10.1016/j.bmcl.2010.02.071 PMID: 20299214	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	EC50	4100 nM	Low	DOI: 10.1016/j.bmcl.2004.12.084 PMID: 15713415	1
Peroxisome proliferator-activated receptor alpha Q07869 E3 ligase component	BindingDB:BDBM28681	Ki	>33300 nM	Low	DOI: 10.1016/s0960-894x(02)01029-6 PMID: 12617924	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	200 nM	Moderate	DOI: 10.1021/jm030621d PMID: 15163205	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	440 nM	Moderate	DOI: 10.1021/jm021027r PMID: 12672231	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	267 nM	Moderate	DOI: 10.1016/j.ejmech.2009.09.042 PMID: 19879669	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	250 nM	Moderate	DOI: 10.1016/s0960-894x(03)00505-5 PMID: 12873517	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	43 nM	High	DOI: 10.1016/j.bmcl.2008.01.126 PMID: 18291645	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	250 nM	Moderate	DOI: 10.1021/jm048993p PMID: 15801817	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	50 nM	High	DOI: 10.1016/s0960-894x(98)00664-7 PMID: 9934490	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	250 nM	Moderate	DOI: 10.1021/jm0496436 PMID: 15771468	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	67 nM	High	DOI: 10.1016/j.bmcl.2006.11.029 PMID: 17129725	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	250 nM	Moderate	DOI: 10.1016/s0960-894x(03)00257-9 PMID: 12729668	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	70 nM	High	DOI: 10.1016/j.bmcl.2004.10.042 PMID: 15582409	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	67 nM	High	DOI: 10.1016/j.bmcl.2006.09.011 PMID: 17005394	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	30 nM	High	DOI: 10.1016/s0960-894x(98)00664-7 PMID: 9934490	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	250 nM	Moderate	DOI: 10.1021/jm900326c PMID: 19719236	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	48 nM	High	DOI: 10.1016/j.bmcl.2006.09.028 PMID: 17005393	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	256 nM	Moderate	DOI: 10.1016/j.bmcl.2007.01.060 PMID: 17292606	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	200 nM	Moderate	DOI: 10.1021/jm900367w PMID: 19530681	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	48 nM	High	DOI: 10.1021/jm0155188 PMID: 11405642	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	210 nM	Moderate	DOI: 10.1016/s0960-894x(03)00115-x PMID: 12657263	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	250 nM	Moderate	DOI: 10.1016/j.bmcl.2005.03.092 PMID: 15863293	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	60 nM	High	DOI: 10.1016/s0960-894x(98)00664-7 PMID: 9934490	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	199 nM	Moderate	DOI: 10.1016/j.bmc.2010.09.068 PMID: 21030263	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	450 nM	Moderate	DOI: 10.1016/j.bmcl.2009.03.036 PMID: 19349176	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	200 nM	Moderate	DOI: 10.1016/j.bmc.2012.11.058 PMID: 23294830	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	92 nM	High	DOI: 10.1021/jm0506930 PMID: 16366601	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	67 nM	High	DOI: 10.1016/j.bmcl.2007.10.047 PMID: 18029178	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	274 nM	Moderate	DOI: 10.1016/j.bmc.2009.09.001 PMID: 19783444	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	2000 nM	Low	DOI: 10.1016/s0960-894x(98)00664-7 PMID: 9934490	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	210 nM	Moderate	DOI: 10.1016/j.bmcl.2005.08.002 PMID: 16153845	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	90 nM	High	DOI: 10.1016/j.bmcl.2006.08.003 PMID: 16919947	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	67 nM	High	DOI: 10.1021/jm060617c PMID: 16970391	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	200 nM	Moderate	DOI: 10.1021/jm900097m PMID: 19507861	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	92 nM	High	DOI: 10.1021/jm0510373 PMID: 16451087	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	IC50	210 nM	Moderate	DOI: 10.1016/j.ejmech.2011.03.040 PMID: 21482446	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	120 nM	Moderate	DOI: 10.1021/jm0301888 PMID: 14695833	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	450 nM	Moderate	DOI: 10.1016/j.bmcl.2009.03.036 PMID: 19349176	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	100 nM	High	DOI: 10.1016/j.bmcl.2010.01.089 PMID: 20138762	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	308 nM	Moderate	DOI: 10.1016/j.bmcl.2006.09.011 PMID: 17005394	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	730 nM	Moderate	DOI: 10.1016/s0960-894x(00)00003-2 PMID: 10714503	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	43 nM	High	DOI: 10.1016/j.bmc.2011.08.003 PMID: 21873070	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	100 nM	High	DOI: 10.1021/jm300911g PMID: 22934537	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	158 nM	Moderate	DOI: 10.1016/j.bmcl.2006.08.110 PMID: 16973358	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	160 nM	Moderate	DOI: 10.1021/jm010964g PMID: 11831892	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	89 nM	High	DOI: 10.1016/j.bmcl.2010.04.031 PMID: 20444603	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	20 nM	High	DOI: 10.1021/jm900097m PMID: 19507861	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	200 nM	Moderate	DOI: 10.1016/j.bmcl.2007.03.015 PMID: 17379517	1
Peroxisome proliferator-activated receptor gamma P37231 E3 ligase component	BindingDB:BDBM28681	EC50	190 nM	Moderate	DOI: 10.1016/j.bmcl.2007.10.041 PMID: 18029176	1