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BDBM291929

E3L013244
Internal ID: BDB013244
Activity data available 3D structure can be prepared
Structure
No local preview file is stored for this compound. The 3D structure can be generated from SMILES before docking.
Basic Properties
Compound ID
E3L013244
Internal ID
BDB013244
Molecular formula
-
Molecular weight
-
Exact mass
-
XLogP
-
TPSA
-
HBA / HBD
- / -
Rotatable bonds
-
Heavy atoms / rings
- / -
Activity summary
IC50 unknown 12.00000000 nM
6 activity record(s) imported
InChIKey
-
SMILES
Aliases
BDBM291929 (preferred) BDBM291929 (source_id)
E3 Relation
E3 UniProt Gene / protein Relation type Ligand role Direct Functional Docking Source Evidence
O75530 EED
Polycomb protein EED		 reported_binder bindingdb_reported Yes No low BindingDB:BDBM291929 medium
; target=Polycomb protein EED; Histone-lysine N-methyltransferase EZH2
Sources and Literature
Source Source ID Source URL Download URL DOI / PMID
BindingDB BDBM291929 Open - 10.7270/Q29W0JNH; 10.7270/Q24T6MD7
Structure Files
Kind Format Status Docking use File / link Preparation note
canonical_2d SMILES raw Reference stored in database keep_parse_failure_review
Activity
Target Source Assay Result Potency Literature Records
Histone-lysine N-methyltransferase EZH2
O75530
E3 ligase component 		BindingDB:BDBM291929 IC50 39 nM High DOI: 10.7270/Q24T6MD7 1
Histone-lysine N-methyltransferase EZH2
O75530
E3 ligase component 		BindingDB:BDBM291929 IC50 12 nM High DOI: 10.7270/Q24T6MD7 1
Histone-lysine N-methyltransferase EZH2
O75530
E3 ligase component 		BindingDB:BDBM291929 IC50 242 nM Moderate DOI: 10.7270/Q24T6MD7 1
Polycomb protein EED
O75530
E3 ligase component 		BindingDB:BDBM291929 IC50 12 nM High DOI: 10.7270/Q29W0JNH 1
Polycomb protein EED
O75530
E3 ligase component 		BindingDB:BDBM291929 IC50 39 nM High DOI: 10.7270/Q29W0JNH 1
Polycomb protein EED
O75530
E3 ligase component 		BindingDB:BDBM291929 IC50 242 nM Moderate DOI: 10.7270/Q29W0JNH 1