| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| P41182 | BCL6;BCL5;LAZ3;ZBTB27;ZNF51 B-cell lymphoma 6 protein |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM522359 | medium ; target=B-cell lymphoma 6 protein |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | COCC(C)(C)Nc1cc(=O)n(C)c2ccc(Nc3ccnc(Cl)c3C#N)cc12 | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB022361/BDB022361.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB022361/BDB022361.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB022361/BDB022361.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB022361/BDB022361.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB022361/BDB022361.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
B-cell lymphoma 6 protein P41182 E3 ligase component |
BindingDB:BDBM522359 | IC50 | 309 nM | Moderate | DOI: 10.7270/Q2320024 | 1 |