| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| Q92794 | KAT6A;MOZ;MYST3;RUNXBP2;ZNF220 Histone acetyltransferase KAT6A |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM534006 | medium ; target=Histone acetyltransferase KAT6A |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | CCOc1ccc(C(C)(C)C)cc1S(=O)(=O)NC(=O)c1cc2c(F)cc(N3CC(F)C3)cc2o1 | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB023224/BDB023224.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB023224/BDB023224.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB023224/BDB023224.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB023224/BDB023224.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB023224/BDB023224.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
Histone acetyltransferase KAT6A Q92794 E3 ligase component |
BindingDB:BDBM534006 | IC50 | 4.48 nM | Very high | DOI: 10.7270/Q20868HP | 1 |