| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| P41182 | BCL6;BCL5;LAZ3;ZBTB27;ZNF51 B-cell lymphoma 6 protein |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM536509 | medium ; target=B-cell lymphoma 6 protein |
| Source | Source ID | Source URL | Download URL | DOI / PMID |
|---|---|---|---|---|
| BindingDB | BDBM536509 | Open | - | 10.7270/Q2Z60S71 |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | CC1Cc2nc3c(c(-c4cc(C(N)=O)c(O)c5c4OCO5)cn3CC(=O)Nc3cc(N4CCOC[C@@H]4C)ncc3Cl)c(=O)n2C1 | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB023843/BDB023843.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB023843/BDB023843.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB023843/BDB023843.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB023843/BDB023843.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB023843/BDB023843.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
B-cell lymphoma 6 protein P41182 E3 ligase component |
BindingDB:BDBM536509 | Kd | 2.14 nM | Very high | DOI: 10.7270/Q2Z60S71 | 1 |