| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| P41182 | BCL6;BCL5;LAZ3;ZBTB27;ZNF51 B-cell lymphoma 6 protein |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM582299 | medium ; target=B-cell lymphoma 6 protein |
| Source | Source ID | Source URL | Download URL | DOI / PMID |
|---|---|---|---|---|
| BindingDB | BDBM582299 | Open | - | 10.7270/Q22B92WK |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | Cc1nc2c(c(-c3cc(C(N)=O)c(O)c4c3OCO4)cn2CC(=O)Nc2cc(N3CCOC[C@@H]3C)ncc2Cl)c(=O)n1C | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB029076/BDB029076.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB029076/BDB029076.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB029076/BDB029076.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB029076/BDB029076.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB029076/BDB029076.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
B-cell lymphoma 6 protein P41182 E3 ligase component |
BindingDB:BDBM582299 | Kd | 2.05 nM | Very high | DOI: 10.7270/Q22B92WK | 1 |