| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| P41182 | BCL6;BCL5;LAZ3;ZBTB27;ZNF51 B-cell lymphoma 6 protein |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM618510 | medium ; target=B-cell lymphoma 6 protein |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | C[C@H]1CCOc2c(c3cc(Nc4nc(-n5ccc(C(F)(F)F)n5)ncc4Cl)ccc3n(C)c2=O)N1 | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB030759/BDB030759.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB030759/BDB030759.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB030759/BDB030759.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB030759/BDB030759.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB030759/BDB030759.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
B-cell lymphoma 6 protein P41182 E3 ligase component |
BindingDB:BDBM618510 | IC50 | 372 nM | Moderate | DOI: 10.7270/Q2RJ4PKC | 1 |