| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| Q9HCI5 | MAGEE1;HCA1;KIAA1587 Melanoma-associated antigen E1 |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM688246 | medium ; target=Melanoma-associated antigen E1 |
| Source | Source ID | Source URL | Download URL | DOI / PMID |
|---|---|---|---|---|
| BindingDB | BDBM688246 | Open | - | 10.7270/Q2PC36P6 |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | COc1cccc(CNCCC/N=C2/C=CNC3=CC=C(CC(C)C)C=CC32)c1O | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB034409/BDB034409.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB034409/BDB034409.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB034409/BDB034409.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB034409/BDB034409.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB034409/BDB034409.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
Melanoma-associated antigen E1 Q9HCI5 E3 ligase component |
BindingDB:BDBM688246 | IC50 | 68500 nM | Low | DOI: 10.7270/Q2PC36P6 | 1 |