| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| Q13619 | CUL4A Cullin-4A |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM748925 | medium ; target=Streptavidin |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | CN(c1ccc(-c2nc(C(=O)O)cc3c2[nH]c2cc(Br)ccc23)cc1)S(=O)(=O)c1ccccc1 | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB038895/BDB038895.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB038895/BDB038895.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB038895/BDB038895.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB038895/BDB038895.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB038895/BDB038895.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
Streptavidin Q13619 E3 ligase component |
BindingDB:BDBM748925 | IC50 | 2500 nM | Low | DOI: 10.7270/Q2959P4M | 1 |
|
Streptavidin Q13619 E3 ligase component |
BindingDB:BDBM748925 | Kd | 25400 nM | Low | DOI: 10.7270/Q2959P4M | 1 |