| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| Q96GG9 | DCUN1D1;DCN1;DCUN1L1;RP42;SCCRO DCN1-like protein 1 |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM768572 | medium ; target=DCN1-like protein 1 |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | Cc1cccc(C(=O)N[C@@H]2C(=O)Nc3c(c(C)nn3-c3ccccc3)[C@H]2c2ccc(C#N)cc2)c1 | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041021/BDB041021.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041021/BDB041021.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041021/BDB041021.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB041021/BDB041021.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB041021/BDB041021.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
DCN1-like protein 1 Q96GG9 E3 ligase component |
BindingDB:BDBM768572 | IC50 | 35 nM | High | DOI: 10.7270/Q2MW2NXW | 1 |
|
DCN1-like protein 1 Q96GG9 E3 ligase component |
BindingDB:BDBM768572 | IC50 | 43 nM | High | DOI: 10.7270/Q2MW2NXW | 1 |