| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| Q96GG9 | DCUN1D1;DCN1;DCUN1L1;RP42;SCCRO DCN1-like protein 1 |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM775405 | medium ; target=DCN1-like protein 1 |
| Source | Source ID | Source URL | Download URL | DOI / PMID |
|---|---|---|---|---|
| BindingDB | BDBM775405 | Open | - | 10.7270/Q25D8XN1 |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | CCN1C(=O)[C@@H](NC(=O)c2nccc(C(F)(F)F)n2)[C@H](c2cccc(NC(=O)C3=CCN(C)C3)c2)c2c(C)nn(-c3ccccc3)c21 | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041791/BDB041791.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041791/BDB041791.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041791/BDB041791.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB041791/BDB041791.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB041791/BDB041791.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
DCN1-like protein 1 Q96GG9 E3 ligase component |
BindingDB:BDBM775405 | IC50 | <200 nM | Uncertain | DOI: 10.7270/Q25D8XN1 | 1 |
|
DCN1-like protein 1 Q96GG9 E3 ligase component |
BindingDB:BDBM775405 | IC50 | 600 nM | Moderate | DOI: 10.7270/Q25D8XN1 | 1 |