| E3 UniProt | Gene / protein | Relation type | Ligand role | Direct | Functional | Docking | Source | Evidence |
|---|---|---|---|---|---|---|---|---|
| Q96GG9 | DCUN1D1;DCN1;DCUN1L1;RP42;SCCRO DCN1-like protein 1 |
reported_binder | bindingdb_reported | Yes | No | low | BindingDB:BDBM775536 | medium ; target=DCN1-like protein 1 |
| Source | Source ID | Source URL | Download URL | DOI / PMID |
|---|---|---|---|---|
| BindingDB | BDBM775536 | Open | - | 10.7270/Q25D8XN1 |
| Kind | Format | Status | Docking use | File / link | Preparation note |
|---|---|---|---|---|---|
| canonical_2d | SMILES | raw | Docking-ready | C/C=C(\CN(C)C1COC1)C(=O)NCc1cccc([C@@H]2c3cnn(-c4ccccc4)c3N(CC)C(=O)[C@H]2NC(=O)c2csc(C(F)(F)F)n2)c1 | keep_bindingdb_unique |
| generated_3d | SDF | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041922/BDB041922.sdf | Generated from canonical SMILES |
| generated_3d | MOL2 | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041922/BDB041922.mol2 | Generated from canonical SMILES |
| docking_ready | PDBQT | prepared | Docking-ready | public/e3_file/ligand_db/generated/BDB041922/BDB041922.pdbqt | Generated from canonical SMILES |
| image | PNG | prepared | Reference | public/e3_file/ligand_db/generated/BDB041922/BDB041922.png | Generated from canonical SMILES |
| image | SVG | prepared | Reference | public/e3_file/ligand_db/generated/BDB041922/BDB041922.svg | Generated from canonical SMILES |
| Target | Source | Assay | Result | Potency | Literature | Records |
|---|---|---|---|---|---|---|
|
DCN1-like protein 1 Q96GG9 E3 ligase component |
BindingDB:BDBM775536 | IC50 | 600 nM | Moderate | DOI: 10.7270/Q25D8XN1 | 1 |
|
DCN1-like protein 1 Q96GG9 E3 ligase component |
BindingDB:BDBM775536 | IC50 | <200 nM | Uncertain | DOI: 10.7270/Q25D8XN1 | 1 |