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L321

E3L067193
Internal ID: LIG001763
E3-ligand related No standardized activity value Local docking-ready structure
Dock with Q8TEB1
Structure
/e3_file/ligand_db/generated/LIG001763/LIG001763.sdf
Basic Properties
Compound ID
E3L067193
Internal ID
LIG001763
Molecular formula
C23H22F3NO4
Molecular weight
433.426000
Exact mass
433.150093
XLogP
5.2270
TPSA
64.6300
HBA / HBD
4 / 1
Rotatable bonds
4
Heavy atoms / rings
31 / 3
Activity summary
No standardized activity value was imported for this source record.
InChIKey
WSXCHSIKNSAQOC-YVLHZVERSA-N
SMILES
Cc1ccc(OCC(=O)OC(C)(C)C)c(/C=C2\C(=O)Nc3cc(C(F)(F)F)ccc32)c1
Aliases
L321 (preferred) e3_ligand:134 (source_id)
E3 Relation
E3 UniProt Gene / protein Relation type Ligand role Direct Functional Docking Source Evidence
Q8TEB1 DCAF11;WDR23;GL014;PRO2389
DDB1- and CUL4-associated factor 11		 direct_binder e3_ligand Yes Yes medium e3_ligand:134 high
DCAF11
Sources and Literature
Source Source ID Source URL Download URL DOI / PMID
e3_ligand 134 - -
Structure Files
Kind Format Status Docking use File / link Preparation note
canonical_2d SMILES raw Docking-ready Cc1ccc(OCC(=O)OC(C)(C)C)c(/C=C2\C(=O)Nc3cc(C(F)(F)F)ccc32)c1 keep_base
generated_3d SDF prepared Docking-ready public/e3_file/ligand_db/generated/LIG001763/LIG001763.sdf Generated from canonical SMILES
generated_3d MOL2 prepared Docking-ready public/e3_file/ligand_db/generated/LIG001763/LIG001763.mol2 Generated from canonical SMILES
docking_ready PDBQT prepared Docking-ready public/e3_file/ligand_db/generated/LIG001763/LIG001763.pdbqt Generated from canonical SMILES
image PNG prepared Reference public/e3_file/ligand_db/generated/LIG001763/LIG001763.png Generated from canonical SMILES
image SVG prepared Reference public/e3_file/ligand_db/generated/LIG001763/LIG001763.svg Generated from canonical SMILES
Activity
Target Source Assay Result Potency Literature Records
No standardized activity value is available in the imported source data for this compound. The E3 relation and literature/source evidence above are still retained for traceability.