| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027861
BDB027861
|
US11458138, Example 314
CN(C)C(=O)C(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H20N6O 336.399000 |
XXSWNVBGGCJPQR-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574434; PubChem:CID135390650
|
Local ready
Direct docking supported
|
|
E3L027862
BDB027862
|
US11458138, Example 315
CN(CCC(C)(C)N)c1nc(-c2ccncc2)nc2cnccc12
|
C18H22N6 322.416000 |
USJDAFDGWHKLDY-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574435; PubChem:CID145744571
|
Local ready
Direct docking supported
|
|
E3L027863
BDB027863
|
US11458138, Example 316
CC(C)(CNC(=O)OC(C)(C)C)CNc1nc(-c2ccncc2)nc2cnccc12
|
C22H28N6O2 408.506000 |
WQXZTZZVNQLVNE-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574436; PubChem:CID145744616
|
Local ready
Direct docking supported
|
|
E3L027864
BDB027864
|
US11458138, Example 317
CC(C)(CN)CNc1nc(-c2ccncc2)nc2cnccc12
|
C17H20N6 308.389000 |
LISLXKHKNUTYFU-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574437; PubChem:CID135368784
|
Local ready
Direct docking supported
|
|
E3L027865
BDB027865
|
US11458138, Example 318
CC(C)(CC(N)=O)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H18N6O 322.372000 |
JETODWGXJQPQJG-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574438; PubChem:CID145744610
|
Local ready
Direct docking supported
|
|
E3L027866
BDB027866
|
US11458138, Example 319
FC(F)(F)[C@H]1CN(c2nc(-c3ccncc3)nc3cnccc23)CCN1
|
C17H15F3N6 360.343000 |
NCWUWMQIMGPXQR-CQSZACIVSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574439; PubChem:CID137350928
|
Local ready
Direct docking supported
|
|
E3L027867
BDB027867
|
example 320 [WO2018198077A2]
CC(C)(N)C(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H22N6 322.416000 |
MYPGOQOVEQKGDN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574440; PubChem:CID135390649
|
Local ready
Direct docking supported
|
|
E3L027868
BDB027868
|
US11458138, Example 321
FC(F)(F)[C@@H]1CN(c2nc(-c3ccncc3)nc3cnccc23)CCN1
|
C17H15F3N6 360.343000 |
NCWUWMQIMGPXQR-AWEZNQCLSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574441; PubChem:CID135368380
|
Local ready
Direct docking supported
|
|
E3L027869
BDB027869
|
US11458138, Example 322
CCOC(=O)C(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H19N5O2 337.383000 |
SMOQHGUVRZLAPT-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574442; PubChem:CID145744607
|
Local ready
Direct docking supported
|
|
E3L027870
BDB027870
|
US11458138, Example 323
CN(C)CC(C)(C)CNc1nc(-c2ccncc2)nc2cnccc12
|
C19H24N6 336.443000 |
ITZNQYLXNRYEHL-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574443; PubChem:CID145744562
|
Local ready
Direct docking supported
|
|
E3L027871
BDB027871
|
US11458138, Example 324
CC(C)(C)Nc1nc(-c2nonc2N)nc2cnccc12
|
C13H15N7O 285.311000 |
ZPTLTQXUNFJSNB-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574444; PubChem:CID135368294
|
Local ready
Direct docking supported
|
|
E3L027872
BDB027872
|
US11458138, Example 325
CN(C)C(C)(C)CNc1nc(-c2ccncc2)nc2cnccc12
|
C18H22N6 322.416000 |
DKTKSNOAXMCFTA-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574445; PubChem:CID135368085
|
Local ready
Direct docking supported
|
|
E3L027873
BDB027873
|
US11458138, Example 326
CC(C)(Nc1nc(-c2ccncc2)nc2cnccc12)C(N)=O
|
C16H16N6O 308.345000 |
UONGWIKGFYVPKT-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574446; PubChem:CID137350817
|
Local ready
Direct docking supported
|
|
E3L027874
BDB027874
|
US11458138, Example 327
C[C@](O)(CNc1cc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C17H15F3N4O 348.328000 |
UVTAWSPFRLIBMN-INIZCTEOSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574447; PubChem:CID135368734
|
Local ready
Direct docking supported
|
|
E3L027875
BDB027875
|
US11458138, Example 328
CC(C)(CCNC(=O)OC(C)(C)C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C22H28N6O2 408.506000 |
IFLQSICQUWYBAW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574448; PubChem:CID145744600
|
Local ready
Direct docking supported
|
|
E3L027876
BDB027876
|
US11458138, Example 329
CN(C)CC(C)(C)CN(C)c1nc(-c2ccncc2)nc2cnccc12
|
C20H26N6 350.470000 |
DZFPOKOZZUSCGA-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574449; PubChem:CID145744561
|
Local ready
Direct docking supported
|
|
E3L027877
BDB027877
|
US11458138, Example 330
CCN(CC)CCC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C21H28N6 364.497000 |
SWEGDJWOWMVNPV-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574450; PubChem:CID137350587
|
Local ready
Direct docking supported
|
|
E3L027878
BDB027878
|
US11458138, Example 331
CN(C)CCC(C)(C)Nc1nc(-c2ccnc(F)c2)nc2cnccc12
|
C19H23FN6 354.433000 |
FRLQLTXVVWDXLN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574451; PubChem:CID135390229
|
Local ready
Direct docking supported
|
|
E3L027879
BDB027879
|
US11458138, Example 332
Cc1n[nH]c(C)c1-c1nc(NC(C)(C)CCN(C)C)c2ccncc2n1
|
C19H27N7 353.474000 |
SHWYBGOPBDGSKM-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574452; PubChem:CID137350805
|
Local ready
Direct docking supported
|
|
E3L027880
BDB027880
|
US11458138, Example 333
CN(C)CCC(C)(C)Nc1nc(-c2c[nH]nc2C(F)(F)F)nc2cnccc12
|
C18H22F3N7 393.417000 |
GRPMEXOJKIUSID-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574453; PubChem:CID145744608
|
Local ready
Direct docking supported
|