| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L028841
BDB028841
|
BDBM581818
Cc1coc(-c2ccnc(SC3CCC(=O)NC3=O)c2)n1
|
C14H13N3O3S 303.343000 |
NDPVVGVYTIFGKQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581818; PubChem:CID142623367
|
Local ready
Direct docking supported
|
|
E3L028842
BDB028842
|
BDBM581819
O=C1CCC(Sc2cc(-c3nn[nH]n3)ccn2)C(=O)N1
|
C11H10N6O2S 290.308000 |
XJLFTIQMZBSNPF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581819; PubChem:CID142623342
|
Local ready
Direct docking supported
|
|
E3L028843
BDB028843
|
BDBM581820
NC(=O)c1cccnc1SC1CCC(=O)NC1=O
|
C11H11N3O3S 265.294000 |
QPMLSNIVNUFWQR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581820; PubChem:CID142623402
|
Local ready
Direct docking supported
|
|
E3L028844
BDB028844
|
BDBM581821
CN(C)C(=O)c1cccnc1SC1CCC(=O)NC1=O
|
C13H15N3O3S 293.348000 |
VGFAOFKRNIVKQJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581821; PubChem:CID142623400
|
Local ready
Direct docking supported
|
|
E3L028845
BDB028845
|
BDBM581823
COCCOCCNC(=O)c1cccnc1SC1CCC(=O)NC1=O
|
C16H21N3O5S 367.427000 |
FITGWZNXNVDZSH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581823; PubChem:CID155261447
|
Local ready
Direct docking supported
|
|
E3L028846
BDB028846
|
BDBM581824
Cn1cccc(N2CCC(=O)NC2=O)c1=O
|
C10H11N3O3 221.216000 |
PVLHPRSYUHGTIR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581824; PubChem:CID155261434
|
Local ready
Direct docking supported
|
|
E3L028847
BDB028847
|
1-(1-Methyl-2-oxoquinolin-3-yl)-1,3-diazinane-2,4-dione
Cn1c(=O)c(N2CCC(=O)NC2=O)cc2ccccc21
|
C14H13N3O3 271.276000 |
WSQJRKFENJVGGL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581825; PubChem:CID142623298
|
Local ready
Direct docking supported
|
|
E3L028848
BDB028848
|
BDBM581826
CN1Cc2ccccc2C(N2CCC(=O)NC2=O)C1=O
|
C14H15N3O3 273.292000 |
XSPVHBXDVCKLDS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581826; PubChem:CID142623290
|
Local ready
Direct docking supported
|
|
E3L028849
BDB028849
|
BDBM581827
Cn1cc2ccccc2c(N2CCC(=O)NC2=O)c1=O
|
C14H13N3O3 271.276000 |
NDYRBPSULNLIQJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581827; PubChem:CID142623348
|
Local ready
Direct docking supported
|
|
E3L028850
BDB028850
|
US11512083, Example 22
CSCC(NC(=O)CCC(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C26H36N4O4S2 532.732000 |
VDESLTPJMGJHJZ-QFMSAKRMSA-N | P40337, P62877, Q13617 | Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM581845; PubChem:CID122529010
|
Local ready
Direct docking supported
|
|
E3L028851
BDB028851
|
US11512083, Example 70
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccccc2C#N)C(C)(C)C)cc1
|
C30H33N5O4S 559.692000 |
NUVIGPMXWRQLFN-KTIWRFAQSA-N | P40337, P62877, Q13617 | Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM581891; PubChem:CID122529076
|
Local ready
Direct docking supported
|
|
E3L028852
BDB028852
|
US11512083, Example 75
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CCN(C)CC2)C(C)(C)C)cc1
|
C29H41N5O4S 555.745000 |
SAXJAVQZJAJIMR-GIFXNVAJSA-N | P40337, P62877, Q13617 | Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM581896; PubChem:CID122529030
|
Local ready
Direct docking supported
|
|
E3L028853
BDB028853
|
WO2023001061, Example 1
CC(C)c1cnn2c(NCc3ccccc3N(C)C)cc(OC3CCN(C)CC3)nc12
|
C24H34N6O 422.577000 |
JCOZOIXEEPDWEC-UHFFFAOYSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM581943; PubChem:CID166594722
|
Local ready
Direct docking supported
|
|
E3L028854
BDB028854
|
US11512083, Example 110
Cc1ncsc1-c1ccc(CNC(=S)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C29H32N4O3S2 548.734000 |
UKCWLXITAYZISN-VJTSUQJLSA-N | P40337, P62877, Q13617 | Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM581946; PubChem:CID122529162
|
Local ready
Direct docking supported
|
|
E3L028855
BDB028855
|
WO2023001061, Example 2
CC(C)c1cnn2c(NCC3CCCN3C)cc(NC[C@H]3CCNC[C@@H]3O)nc12
|
C21H35N7O 401.559000 |
QQLSIJHLYVKUPE-AGPBCMBSSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM581947; PubChem:CID166594725
|
Local ready
Direct docking supported
|
|
E3L028856
BDB028856
|
WO2023001061, Example 4
CC(C)c1cnn2c(NCc3nc4cc(N(C)C)ccc4s3)cc(NC[C@H]3CCNC[C@@H]3O)nc12
|
C25H34N8OS 494.669000 |
NXRKFXLYXYGWNQ-UZLBHIALSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM581954; PubChem:CID166594732
|
Local ready
Direct docking supported
|
|
E3L028857
BDB028857
|
WO2023001061, Example 5
CC(C)c1cnn2c(NCc3ccc4cccc(N(C)C)c4n3)cc(NC[C@H]3CCNC[C@@H]3O)nc12
|
C27H36N8O 488.640000 |
SKBSWOBKDUUYNC-XXBNENTESA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM581955; PubChem:CID166594733
|
Local ready
Direct docking supported
|
|
E3L028858
BDB028858
|
WO2023001061, Example 6
CC(C)c1cnn2c(NCc3ccnn3C)cc(NC[C@H]3CCNC[C@@H]3O)nc12
|
C20H30N8O 398.515000 |
ZLSKNJNVHQBNSQ-PBHICJAKSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM581956; PubChem:CID166594734
|
Local ready
Direct docking supported
|
|
E3L028859
BDB028859
|
WO2023001061, Example 7
CC(C)c1cnn2c(NCc3ccnn3C)cc(OC3CCN(C)CC3)nc12
|
C20H29N7O 383.500000 |
IPIBQKDBYRSOMN-UHFFFAOYSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM581957; PubChem:CID166594735
|
Local ready
Direct docking supported
|
|
E3L028860
BDB028860
|
WO2023001061, Example 8
CC(C)c1cnn2c(NCC3CCCN3C)cc(OC3CCN(C)CC3)nc12
|
C21H34N6O 386.544000 |
AZQXMHJPBLALOY-UHFFFAOYSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM581958; PubChem:CID166594736
|
Local ready
Direct docking supported
|