| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L033621
BDB033621
|
BDBM663044
COc1cc(C)nc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c3c(c12)OCC1CC31
|
C23H23N5O6S 497.533000 |
PHKZLXXNSPCUGK-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM663044; PubChem:CID169861018
|
Local ready
Direct docking supported
|
|
E3L033622
BDB033622
|
BDBM667864
CNC(=O)Cn1cc(-c2ccc3c(c2)C(F)CC32NC(=O)N(CC(=O)N(Cc3ccc(F)cc3)C(C)C(F)(F)F)C2=O)cn1
|
C29H27F5N6O4 618.563000 |
SWXCHCQCWFXILM-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM667864
|
Local ready
Direct docking supported
|
|
E3L033623
BDB033623
|
BDBM667873
O=C(Nc1ccc2[nH]ncc2n1)C1CC(F)CN1C(=O)C1(c2ccc(OC(F)F)cc2)CCC(F)(F)CC1
|
C25H24F5N5O3 537.489000 |
IGBIPTRCWSVZCO-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM667873; PubChem:CID168311716
|
Local ready
Direct docking supported
|
|
E3L033624
BDB033624
|
BDBM667874
CCN(CC)c1ccc(-c2nc3cc(C(=O)NC)ccc3n2Cc2ccn(CC)n2)cn1
|
C24H29N7O 431.544000 |
LYVJDLHFTGYNAV-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM667874; PubChem:CID138466007
|
Local ready
Direct docking supported
|
|
E3L033625
BDB033625
|
BDBM667878
CC(N(Cc1ccc(F)cc1)C(=O)CN1C(=O)N[C@]2(CCc3cc(-c4cnn(C)c4)ccc32)C1=O)C(F)(F)F
|
C27H25F4N5O3 543.521000 |
IBWWGICKBQHEBM-TZHIXCAUSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM667878
|
Local ready
Direct docking supported
|
|
E3L033626
BDB033626
|
BDBM667882
CNC(=O)Nc1ccc2c(c1)CC[C@]21OC(=O)N(CC(=O)N(Cc2ccc(F)cc2)C(C)C(F)(F)F)C1=O
|
C25H24F4N4O5 536.482000 |
VRVJKILQRBSEAG-UUTCKOJZSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM667882
|
Local ready
Direct docking supported
|
|
E3L033627
BDB033627
|
BDBM667885
CNC(=O)Nc1ccc2c(c1)CC[C@@]21OC(=O)N(CC(=O)N2[C@@H](C)CC[C@H]2c2cc(F)c(F)c(F)c2)C1=O
|
C26H25F3N4O5 530.503000 |
IJJKARUZCHPVKL-VLXUNYGLSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM667885; PubChem:CID146634795
|
Local ready
Direct docking supported
|
|
E3L033628
BDB033628
|
BDBM667886
CCn1ncc(CN(C)C(=O)c2cc(-c3ccc(NC4CN(C)C4)c(C)n3)nc3ccc(Cl)cc23)c1C
|
C28H32ClN7O 518.065000 |
GYCCIEWETQNUJP-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM667886; PubChem:CID165943540
|
Local ready
Direct docking supported
|
|
E3L033629
BDB033629
|
BDBM668626
CNS(=O)(=O)Nc1cccc(Cc2c(CC(=O)NOCCO)c3ccc(Oc4ncccn4)cc3oc2=O)c1F
|
C25H24FN5O8S 573.559000 |
FUMSHCTVBNTKPB-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM668626; PubChem:CID156808717
|
Local ready
Direct docking supported
|
|
E3L033630
BDB033630
|
BDBM668627
CNS(=O)(=O)NCC(=O)N(Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F)OC
|
C20H23F3IN5O7S 661.397000 |
IHWHZUVPXIRKBX-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM668627; PubChem:CID156808763
|
Local ready
Direct docking supported
|
|
E3L033631
BDB033631
|
BDBM668628
[C][N]S(=O)(=O)Nc1nccc([C]c2cc(C([N])=O)c([N]c3ccc([C]4[C][C]4)cc3F)c(F)c2F)c1F
|
C23H7F4N5O3S 509.400000 |
SLRZYEOILRUAMR-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB
BindingDB:BDBM668628
|
Local ready
Direct docking supported
|
|
E3L033632
BDB033632
|
BDBM668649
NC(=O)c1cc(Cc2ccnc(NS(=O)(=O)NC3C4CCOC43)c2F)c(F)c(F)c1Nc1ccc(I)cc1F
|
C24H20F4IN5O4S 677.418000 |
IRCLZLJAEFQVQA-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM668649; PubChem:CID166571060
|
Local ready
Direct docking supported
|
|
E3L033633
BDB033633
|
BDBM668670
CNS(C)(=O)=Nc1nccc(Cc2cc(C(N)=O)c(Nc3ccc(I)cc3F)c(F)c2F)c1F
|
C21H18F4IN5O2S 607.371000 |
QUIWMANKWJDNGK-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM668670; PubChem:CID156808943
|
Local ready
Direct docking supported
|
|
E3L033634
BDB033634
|
BDBM668752
CNS(=O)(=O)Nc1nccc(Cc2cc(C(N)=O)c(Nc3ccc4sccc4c3F)c(F)c2F)c1F
|
C22H17F4N5O3S2 539.536000 |
MWLIRBVDTHSBRM-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM668752; PubChem:CID156808912
|
Local ready
Direct docking supported
|
|
E3L033635
BDB033635
|
BDBM668787
CNS(=O)(=O)Nc1nccc(Cc2cc(C(N)=O)c(Nc3ccc(I)cc3F)cn2)c1F
|
C19H17F2IN6O3S 574.351000 |
RSMGUCWXMLOUPS-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM668787; PubChem:CID156808864
|
Local ready
Direct docking supported
|
|
E3L033636
BDB033636
|
BDBM669520
O=C1CCC(N2C(=O)c3ccc(NS(=O)(=O)c4cccc(OC(F)(F)F)c4)cc3C2=O)C(=O)N1
|
C20H14F3N3O7S 497.407000 |
ITYXEJVELHAHBC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM669520; PubChem:CID164938650
|
Local ready
Direct docking supported
|
|
E3L033637
BDB033637
|
BDBM669521
Cc1c(Cl)cccc1S(=O)(=O)Nc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C20H16ClN3O6S 461.883000 |
FURMQZYSFFTQLK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM669521; PubChem:CID164938641
|
Local ready
Direct docking supported
|
|
E3L033638
BDB033638
|
BDBM669522
Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1Cl
|
C20H16ClN3O6S 461.883000 |
WVKNOEMSHFZOMC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM669522; PubChem:CID166628182
|
Local ready
Direct docking supported
|
|
E3L033639
BDB033639
|
BDBM669523
O=C1CCC(N2C(=O)c3ccc(NS(=O)(=O)c4ccccc4)cc3C2=O)C(=O)N1
|
C19H15N3O6S 413.411000 |
HLZCITRKGRESDX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM669523; PubChem:CID164938565
|
Local ready
Direct docking supported
|
|
E3L033640
BDB033640
|
BDBM669892
CC[C@@H]1CN(Cc2cc(C(c3ccc(C(C)=O)s3)C(C)C(=O)O)ccc2C)S(=O)(=O)c2ccccc2O1
|
C28H31NO6S2 541.691000 |
SXWNSUAILRJZLR-ZYCCDCAPSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB
BindingDB:BDBM669892
|
Local ready
Direct docking supported
|