| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035821
BDB035821
|
BDBM711118
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5CC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C27H28F3N5O2 511.548000 |
DOOAVVHTJOUEHG-AEEMYVKYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711118
|
Local ready
Direct docking supported
|
|
E3L035822
BDB035822
|
BDBM711119
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CN5CC(C)(O)C5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C28H30F3N5O3 541.574000 |
CRLVGIJHOWRLRU-DXKIZBQOSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711119
|
Local ready
Direct docking supported
|
|
E3L035823
BDB035823
|
BDBM711120
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5(C)COC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C28H30F3N5O3 541.574000 |
JRWGRRAZERPDRL-DXKIZBQOSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711120
|
Local ready
Direct docking supported
|
|
E3L035824
BDB035824
|
BDBM711121
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CN5CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C27H28F3N5O2 511.548000 |
XMHIFHZIDAUFLT-AEEMYVKYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711121
|
Local ready
Direct docking supported
|
|
E3L035825
BDB035825
|
BDBM711122
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNCC(C)(C)C)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H34F3N5O2 541.618000 |
NULDFISJLMZSAB-BFZJZIARSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711122
|
Local ready
Direct docking supported
|
|
E3L035826
BDB035826
|
BDBM711123
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNCC5CC5(F)F)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C28H28F5N5O2 561.555000 |
WXRUDQFELXWJCU-ZFTSLGCYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711123
|
Local ready
Direct docking supported
|
|
E3L035827
BDB035827
|
BDBM711124
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNCC(C)(C)F)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C28H31F4N5O2 545.581000 |
QMTYIXIBNREJSV-DXKIZBQOSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711124
|
Local ready
Direct docking supported
|
|
E3L035828
BDB035828
|
BDBM711125
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CN[C@]5(C)C[C@H](O)C5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H32F3N5O3 555.601000 |
XTPDXOIFCVXBFL-IHZWUNNNSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711125
|
Local ready
Direct docking supported
|
|
E3L035829
BDB035829
|
BDBM711126
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC56CC(C5)C6)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H30F3N5O2 537.586000 |
BJFQIPBUHJGODW-HDALJVDKSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711126
|
Local ready
Direct docking supported
|
|
E3L035830
BDB035830
|
BDBM711127
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNCC5(F)CC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C28H29F4N5O2 543.565000 |
VHQXIHUOSBKLPW-DXKIZBQOSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711127
|
Local ready
Direct docking supported
|
|
E3L035831
BDB035831
|
BDBM711128
COCC1(NCc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(c5nncn5C)C[C@H](OC)C4)c2)C3=O)CC1
|
C29H32F3N5O3 555.601000 |
WQGHFGVHDRESMV-BFZJZIARSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711128
|
Local ready
Direct docking supported
|
|
E3L035832
BDB035832
|
BDBM711129
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5CC(C)(C)C5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
LSAMUOBRDYZNIN-FXBOJIBUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711129
|
Local ready
Direct docking supported
|
|
E3L035833
BDB035833
|
BDBM711130
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNCC5(CO)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O3 569.628000 |
VSTQXNKWCGAHLW-FXBOJIBUSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711130
|
Local ready
Direct docking supported
|
|
E3L035834
BDB035834
|
BDBM711131
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CN5CCCCCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
RVOAIHCSSLBNKH-CBHYQUCXSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711131
|
Local ready
Direct docking supported
|
|
E3L035835
BDB035835
|
BDBM711132
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNCCOC(F)F)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C27H28F5N5O3 565.543000 |
MKGFHPAZLLBPRL-KQODVJPSSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711132
|
Local ready
Direct docking supported
|
|
E3L035836
BDB035836
|
BDBM711133
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CN[C@H]5[C@@H]6COC[C@@H]65)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H30F3N5O3 553.585000 |
LVMHOSWIQIITGR-LEAWBQNXSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711133
|
Local ready
Direct docking supported
|
|
E3L035837
BDB035837
|
BDBM711134
COCCC1(NCc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(c5nncn5C)C[C@H](OC)C4)c2)C3=O)CCC1
|
C31H36F3N5O3 583.655000 |
KMVCEFDNCZLTGI-HWSBAZIVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711134
|
Local ready
Direct docking supported
|
|
E3L035838
BDB035838
|
BDBM711135
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5CC(C(F)F)C5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H30F5N5O2 575.582000 |
OYGDJHWZWUTPMA-TXPILHJISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711135
|
Local ready
Direct docking supported
|
|
E3L035839
BDB035839
|
BDBM711136
COCC1(NCc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(c5nncn5C)C[C@H](OC)C4)c2)C3=O)CCC1
|
C30H34F3N5O3 569.628000 |
BAOWWNRTEZQOKD-FXBOJIBUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM711136
|
Local ready
Direct docking supported
|
|
E3L035840
BDB035840
|
BDBM711137
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNCC5(CF)CC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H31F4N5O2 557.592000 |
KDUCSKMHFONFKI-BFZJZIARSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM711137
|
Local ready
Direct docking supported
|