| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L040821
BDB040821
|
BDBM765908
COc1c(N2CC(C)(Nc3nnc(-c4ccc(OC(F)(F)F)cc4)o3)C2)ccc(C2CCC(=O)NC2=O)c1F
|
C25H23F4N5O5 549.481000 |
BMWBNKJHFNLPSB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765908; PubChem:CID171541366
|
Local ready
Direct docking supported
|
|
E3L040822
BDB040822
|
BDBM765909
O=C1CCC(c2c(F)cc(N3CC(NC(=O)OC45CC(C(=O)c6ccccc6)(C4)C5)C3)cc2F)C(=O)N1
|
C27H25F2N3O5 509.509000 |
XGUZWITYIMHDPA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765909; PubChem:CID171541247
|
Local ready
Direct docking supported
|
|
E3L040823
BDB040823
|
BDBM765910
CN(C(=O)N1CC(OC(=O)NC2CN(c3cc(F)c(C4CCC(=O)NC4=O)c(F)c3)C2)C1)c1ccc(Cl)cc1
|
C26H26ClF2N5O5 561.973000 |
SYHMXJVGXHSWAF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765910; PubChem:CID171540880
|
Local ready
Direct docking supported
|
|
E3L040824
BDB040824
|
BDBM765911
COC12CC(c3nnc(N[C@H]4CN(c5cc(F)c(C6CCC(=O)NC6=O)c(F)c5)[C@@H]4C)o3)(C1)C2
|
C23H25F2N5O4 473.480000 |
OVHMMMSSADKXJT-RCWBWRNKSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765911; PubChem:CID171541248
|
Local ready
Direct docking supported
|
|
E3L040825
BDB040825
|
CDK2 degrader 6
C[C@@H]1[C@@H](Nc2nnc(C34CC(C(F)(F)F)(C3)C4)o2)CN1c1cc(F)c(C2CCC(=O)NC2=O)c(F)c1
|
C23H22F5N5O3 511.451000 |
DYUMYEGVQNMNAQ-SRJWQNMQSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765912; PubChem:CID171540804
|
Local ready
Direct docking supported
|
|
E3L040826
BDB040826
|
BDBM765913
C[C@@H]1[C@@H](Nc2nnc(-c3ccc(C(F)(F)F)cc3)o2)CN1c1cc(F)c(C2CCC(=O)NC2=O)c(F)c1
|
C24H20F5N5O3 521.446000 |
YUINRNLIHYNIEX-JYXGGTNWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765913; PubChem:CID171541283
|
Local ready
Direct docking supported
|
|
E3L040827
BDB040827
|
BDBM765914
C[C@@H]1[C@@H](Nc2nnc(C3CC4(CCC4)C3)o2)CN1c1cc(F)c(C2CCC(=O)NC2=O)c(F)c1
|
C24H27F2N5O3 471.508000 |
IATDMMGSZYXDGP-YOAWFHMFSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765914; PubChem:CID171541249
|
Local ready
Direct docking supported
|
|
E3L040828
BDB040828
|
BDBM765915
Cc1ccc(-c2nnc(N[C@H]3CN(c4cc(F)c(C5CCC(=O)NC5=O)c(F)c4)[C@@H]3C)o2)cc1
|
C24H23F2N5O3 467.476000 |
QBSNBWPPAUHZCL-LHQUYYRUSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765915; PubChem:CID171541354
|
Local ready
Direct docking supported
|
|
E3L040829
BDB040829
|
BDBM765916
C[C@@H]1[C@@H](Nc2nnc(-c3ccc(OC(F)(F)F)cc3)o2)CN1c1cc(F)c(C2CCC(=O)NC2=O)c(F)c1
|
C24H20F5N5O4 537.445000 |
BFXCITLRIAUJBZ-JYXGGTNWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765916; PubChem:CID171541037
|
Local ready
Direct docking supported
|
|
E3L040830
BDB040830
|
BDBM767015
CC1(C)[C@@H]2CC[C@@]1(C)[C@@H](NCCCCCCCSc1cc(F)cc3c1CN(C1CCC(=O)NC1=O)C3=O)C2
|
C30H42FN3O3S 543.749000 |
VBLVITILMKOXIU-PCCFYNKWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767015; PubChem:CID171064771
|
Local ready
Direct docking supported
|
|
E3L040831
BDB040831
|
BDBM767016
O=C1CCC(N2Cc3c(SCc4ccc(CN5CCCCC5)cc4)cc(F)cc3C2=O)C(=O)N1
|
C26H28FN3O3S 481.593000 |
YLWYDQGIZRNLGU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767016; PubChem:CID171064776
|
Local ready
Direct docking supported
|
|
E3L040832
BDB040832
|
BDBM767017
CC1(C)[C@@H]2CC[C@@]1(C)[C@@H](NCc1ccc(CSc3cc(F)cc4c3CN(C3CCC(=O)NC3=O)C4=O)cc1)C2
|
C31H36FN3O3S 549.712000 |
ACWBKLJXCODPBH-HJYHPAORSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767017; PubChem:CID171064756
|
Local ready
Direct docking supported
|
|
E3L040833
BDB040833
|
BDBM767018
O=C1CCC(N2Cc3c(SCc4ccc(CN5CCC(F)(F)CC5)cc4)cc(F)cc3C2=O)C(=O)N1
|
C26H26F3N3O3S 517.573000 |
RZQCOUFHRBMYRP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767018; PubChem:CID171064718
|
Local ready
Direct docking supported
|
|
E3L040834
BDB040834
|
BDBM767019
O=C1CCC(N2Cc3c(SCc4ccc(CNC56CC7CC(CC(C7)C5)C6)cc4)cc(F)cc3C2=O)C(=O)N1
|
C31H34FN3O3S 547.696000 |
STEUXVAQXNBEHB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767019; PubChem:CID171064802
|
Local ready
Direct docking supported
|
|
E3L040835
BDB040835
|
BDBM767020
O=C1CCC(N2Cc3c(SCCCCNC45CC6CC(CC(C6)C4)C5)cc(F)cc3C2=O)C(=O)N1
|
C27H34FN3O3S 499.652000 |
FOLIWBDPHQNZRP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767020; PubChem:CID171064742
|
Local ready
Direct docking supported
|
|
E3L040836
BDB040836
|
BDBM767021
O=C1CCC(N2Cc3c(SCCCCCCCNC4CC5(CCC5)C4)cc(F)cc3C2=O)C(=O)N1
|
C27H36FN3O3S 501.668000 |
LWEAQKHWAAUROQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767021; PubChem:CID171064716
|
Local ready
Direct docking supported
|
|
E3L040837
BDB040837
|
BDBM767022
O=C1CCC(N2Cc3c(SCCCCCCCCN4CCOCC4)cc(F)cc3C2=O)C(=O)N1
|
C25H34FN3O4S 491.629000 |
JCOBXKJQIZSWAM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767022; PubChem:CID176049310
|
Local ready
Direct docking supported
|
|
E3L040838
BDB040838
|
BDBM767023
O=C1CCC(N2Cc3c(CCCCCCCCNC45CC6CC(CC(C6)C4)C5)cc(F)cc3C2=O)C(=O)N1
|
C31H42FN3O3 523.693000 |
LCKHISXQUARKIS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767023; PubChem:CID171064759
|
Local ready
Direct docking supported
|
|
E3L040839
BDB040839
|
BDBM767024
CCN(CC)CCCCCCCCSc1cc(F)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C25H36FN3O3S 477.646000 |
IZCSZHGYWCPWBH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767024; PubChem:CID171064725
|
Local ready
Direct docking supported
|
|
E3L040840
BDB040840
|
BDBM767025
O=C1CCC(N2Cc3c(SCc4ccc(CN5CCC(F)(F)CC5)c(F)c4)cc(F)cc3C2=O)C(=O)N1
|
C26H25F4N3O3S 535.563000 |
FENGHDGRJVQDJA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM767025; PubChem:CID171064724
|
Local ready
Direct docking supported
|