| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L045301
BDB045301
|
BDBM50069627
CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCNC3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21
|
C34H39Cl2N5O2S 652.692000 |
XLBQSMBISPUIMT-MAMXRPNDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069627
|
Local ready
Direct docking supported
|
|
E3L045302
BDB045302
|
BDBM50069628
CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCNC3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)c(F)c3)N21
|
C34H38Cl2FN5O2S 670.682000 |
LIFXVTDIRXSOPW-ZNGXGWPMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069628
|
Local ready
Direct docking supported
|
|
E3L045303
BDB045303
|
BDBM50069629
CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CCNC3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21
|
C33H37Cl2FN6O2S 671.670000 |
FZPRQVYQBJKIQG-KERGWKIMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069629
|
Local ready
Direct docking supported
|
|
E3L045304
BDB045304
|
BDBM50069630
CC(C)C1=C(C(=O)N2[C@H](C)CC[C@H]2C(=O)N2CC3(CC3)NC[C@@H]2C)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21
|
C34H39Cl2FN6O2S 685.697000 |
KUZMUIBQNCSWPP-BYJYTBDMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069630
|
Local ready
Direct docking supported
|
|
E3L045305
BDB045305
|
BDBM50069631
CC(C)C1=C(C(=O)N2C[C@H](F)C[C@H]2C(=O)N2CC3(CC3)NC[C@@H]2C)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21
|
C33H36Cl2F2N6O2S 689.660000 |
OKIDBNYMCUVSLU-QSSUNTQZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069631
|
Local ready
Direct docking supported
|
|
E3L045306
BDB045306
|
BDBM50069632
CC[C@@H]1CNC2(CC2)CN1C(=O)[C@@H]1C[C@@H](F)CN1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)nc3)[C@H]2c2ccc(Cl)c(F)c2)S1
|
C34H38Cl2F2N6O2S 703.687000 |
QUYOIFDRHGZSFZ-YABFKZQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069632
|
Local ready
Direct docking supported
|
|
E3L045307
BDB045307
|
ML323
Cc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-n2ccnn2)cc1
|
C23H24N6 384.487000 |
VUIRVWPJNKZOSS-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48, Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM50069762; PubChem:CID60167849
|
Local ready
Direct docking supported
|
|
E3L045308
BDB045308
|
2-Phenylnaphtho[2,3-D]oxazole-4,9-dione
O=C1c2ccccc2C(=O)c2oc(-c3ccccc3)nc21
|
C17H9NO3 275.263000 |
CMYQQADDUUDCCA-UHFFFAOYSA-N | Q8TAF3 | WD repeat-containing protein 48 |
BindingDB, PubChem
BindingDB:BDBM50069763; PubChem:CID509070
|
Local ready
Direct docking supported
|
|
E3L045309
BDB045309
|
BDBM50069769
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2F)[C@H]1c1ccc(Cl)cc1
|
C29H34Cl2FNO5S 598.564000 |
HUXQNTCNYMUORT-KVFVXYHUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50069769; PubChem:CID118730174
|
Local ready
Direct docking supported
|
|
E3L045310
BDB045310
|
BDBM50069779
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N2CC(C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H40Cl2N2O6S 663.664000 |
SETAPPWUUITUNL-UNVYQVKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069779
|
Local ready
Direct docking supported
|
|
E3L045311
BDB045311
|
BDBM50069780
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N[C@H]2C[C@@H](C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C34H42Cl2N2O6S 677.691000 |
LASZTPUNWIOFCD-OJLCMILUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069780
|
Local ready
Direct docking supported
|
|
E3L045312
BDB045312
|
BDBM50069781
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N[C@H]2C[C@H](C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C34H42Cl2N2O6S 677.691000 |
LASZTPUNWIOFCD-MQXPBDQNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069781
|
Local ready
Direct docking supported
|
|
E3L045313
BDB045313
|
BDBM50069782
CC1(C(=O)O)CCN(C(=O)C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)CC1
|
C36H46Cl2N2O6S 705.745000 |
CJCKYZRDBDLOND-NLNUXBGRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069782
|
Local ready
Direct docking supported
|
|
E3L045314
BDB045314
|
BDBM50069783
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N2CCC(C(=O)O)CC2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C35H44Cl2N2O6S 691.718000 |
HWQABLRWBNVPEA-FHSDPBSVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069783
|
Local ready
Direct docking supported
|
|
E3L045315
BDB045315
|
BDBM50069784
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)NC23CCC(C(=O)O)(CC2)CC3)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C38H48Cl2N2O6S 731.783000 |
LKAFLOJDLRJSEW-BTIIEKRBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069784
|
Local ready
Direct docking supported
|
|
E3L045316
BDB045316
|
BDBM50069785
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N[C@H]2CC[C@@H](C(=O)O)CC2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C36H46Cl2N2O6S 705.745000 |
FJPANYABHZXLHT-YKIGISQSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069785
|
Local ready
Direct docking supported
|
|
E3L045317
BDB045317
|
BDBM50069786
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N[C@H]2CC[C@H](C(=O)O)CC2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C36H46Cl2N2O6S 705.745000 |
FJPANYABHZXLHT-DYBNVOJMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069786
|
Local ready
Direct docking supported
|
|
E3L045318
BDB045318
|
BDBM50069787
CN(C(=O)C[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(=O)(=O)C(C)(C)C)C2CC2)C1=O)c1ccc(C(=O)O)cc1
|
C37H42Cl2N2O6S 713.724000 |
QVCKQBFDNHFPSU-VYUOYPLNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069787
|
Local ready
Direct docking supported
|
|
E3L045319
BDB045319
|
BDBM50069788
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2ccc(CC(=O)O)cc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C37H42Cl2N2O6S 713.724000 |
NUDVETAHJOGXOQ-VIUCBDPOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069788
|
Local ready
Direct docking supported
|
|
E3L045320
BDB045320
|
BDBM50069789
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)Nc2ccc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C35H39Cl2N3O6S 700.685000 |
UQSDNKFAAYCQSH-KHRUNOBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50069789
|
Local ready
Direct docking supported
|