| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L049321
BDB049321
|
BDBM50237742
CS(=O)(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
|
C30H28Cl2FN3O4S 616.542000 |
AHTJRHHYOWHGMT-RFJFUGTDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237742
|
Local ready
Direct docking supported
|
|
E3L049322
BDB049322
|
BDBM50237743
NC(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1
|
C30H27Cl2FN4O3 581.475000 |
GUDSBGCNSIMLIH-LOLKONATSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237743
|
Local ready
Direct docking supported
|
|
E3L049323
BDB049323
|
BDBM50237744
O=C(NC12CCC(C(=O)O)(CC1)CC2)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C32H34Cl2FN3O4 614.545000 |
GFHXXZFENCYUAR-KIPSGEISSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237744
|
Local ready
Direct docking supported
|
|
E3L049324
BDB049324
|
BDBM50237745
CC1(C)CCC2(CC1)N[C@@H](C(=O)N[C@H]1CC[C@H](O)CC1)[C@H](c1cccc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc21
|
C31H36Cl2FN3O3 588.551000 |
XYVIMIHFMVWPSL-HRXTXRLQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237745
|
Local ready
Direct docking supported
|
|
E3L049325
BDB049325
|
BDBM50237746
O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3nc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C28H31Cl2FN4O3 561.485000 |
GGCMPMXRTAOSBN-SQZAJNBOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237746
|
Local ready
Direct docking supported
|
|
E3L049326
BDB049326
|
BDBM50237747
CC1(C)CCC2(CC1)N[C@@H](C(=O)Nc1ccc(C(=O)O)cc1)[C@H](c1cccc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc21
|
C32H30Cl2FN3O4 610.513000 |
MWSDRCOLJKUUNJ-IRUJERLZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237747
|
Local ready
Direct docking supported
|
|
E3L049327
BDB049327
|
BDBM50237748
O=C(N[C@H]1CC[C@@H](C(=O)O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C30H32Cl2FN3O4 588.507000 |
XIKFXEUSDBQREV-PGVSUWNVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237748
|
Local ready
Direct docking supported
|
|
E3L049328
BDB049328
|
BDBM50237749
O=C(NC1CCS(=O)(=O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C28H30Cl2FN3O4S 594.536000 |
JMCLVXKBHPRUJU-ZQIDGUAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237749
|
Local ready
Direct docking supported
|
|
E3L049329
BDB049329
|
BDBM50237750
O=C(NC12CC(C(=O)O)(C1)C2)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C29H28Cl2FN3O4 572.464000 |
NLOAAQVEPPPINN-XYSUXJPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237750
|
Local ready
Direct docking supported
|
|
E3L049330
BDB049330
|
BDBM50237751
Cc1oc([C@H]2[C@H](c3cccc(Cl)c3F)[C@]3(C(=O)Nc4cc(Cl)ccc43)C3(CCCCC3)N2C)nc1C(=O)O
|
C28H26Cl2FN3O4 558.437000 |
HXDRUAKPXCZJIL-QHLUZPDOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237751
|
Local ready
Direct docking supported
|
|
E3L049331
BDB049331
|
BDBM50237752
O=C(O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)c(F)c1
|
C30H25Cl2F2N3O4 600.449000 |
LCUYAMKESYPQRA-LOLKONATSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237752
|
Local ready
Direct docking supported
|
|
E3L049332
BDB049332
|
BDBM50237753
CN1[C@@H](c2nc(C(=O)O)co2)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2
|
C27H24Cl2FN3O4 544.410000 |
SDQGKDMQMLBURH-ZVUIFXONSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237753
|
Local ready
Direct docking supported
|
|
E3L049333
BDB049333
|
BDBM50237754
O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCOCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C28H30Cl2FN3O4 562.469000 |
PIRIGUPRWKOENE-XLKFOPSHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237754
|
Local ready
Direct docking supported
|
|
E3L049334
BDB049334
|
BDBM50237755
Cc1noc([C@H]2[C@H](c3cccc(Cl)c3F)[C@]3(C(=O)Nc4cc(Cl)ccc43)C3(CCCCC3)N2C)n1
|
C26H25Cl2FN4O2 515.416000 |
CPSTWDSJYKRSHU-UNIVCBNLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237755
|
Local ready
Direct docking supported
|
|
E3L049335
BDB049335
|
BDBM50237756
O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3nc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
|
C27H30Cl2FN5O3 562.473000 |
MJJCXOOWFADSEU-HTIZSKPGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237756
|
Local ready
Direct docking supported
|
|
E3L049336
BDB049336
|
BDBM50237757
COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C31H29Cl2FN4O4 611.501000 |
UHIQBNVSXIUHNI-UZXRVZLOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237757
|
Local ready
Direct docking supported
|
|
E3L049337
BDB049337
|
BDBM50237758
Cc1nnc([C@H]2[C@H](c3cccc(Cl)c3F)[C@]3(C(=O)Nc4cc(Cl)ccc43)C3(CCCCC3)N2C)s1
|
C26H25Cl2FN4OS 531.484000 |
WTORRTZLJDUDIQ-UNIVCBNLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237758
|
Local ready
Direct docking supported
|
|
E3L049338
BDB049338
|
BDBM50237759
O=C(N[C@H]1CC[C@H](C(=O)O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C30H32Cl2FN3O4 588.507000 |
XIKFXEUSDBQREV-QUGLQKSYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237759
|
Local ready
Direct docking supported
|
|
E3L049339
BDB049339
|
BDBM50237761
O=C(N[C@H]1CC[C@H](O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
|
C28H31Cl2FN4O3 561.485000 |
SVPUTTATZUOKNA-ZXJBABCFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237761
|
Local ready
Direct docking supported
|
|
E3L049340
BDB049340
|
BDBM50237762
O=C(NC[C@H]1CC[C@H](C(=O)O)CC1)[C@@H]1NC2(CCCCC2)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C31H34Cl2FN3O4 602.534000 |
TURZYRGEJPLUDI-BGBDWYERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50237762
|
Local ready
Direct docking supported
|