| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L050201
BDB050201
|
BDBM50260847
O=C1C[C@@H]2CS[C@]3(C(=O)Nc4cccc(Br)c43)[C@H](c3ccc(Br)cc3)[C@H]2CN1c1cccc(F)c1
|
C27H21Br2FN2O2S 616.350000 |
GWYBMHHREXPSEH-CDOHHPMZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260847; PubChem:CID137645229
|
Local ready
Direct docking supported
|
|
E3L050202
BDB050202
|
BDBM50260848
O=C1C[C@@H]2CS[C@]3(C(=O)Nc4cccc(Br)c43)[C@H](c3ccc(Br)cc3)[C@H]2CN1c1ccc(Cl)cc1
|
C27H21Br2ClN2O2S 632.805000 |
DTTGAEDWRSAUJA-CDOHHPMZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260848; PubChem:CID137642800
|
Local ready
Direct docking supported
|
|
E3L050203
BDB050203
|
BDBM50260849
O=C1C[C@@H]2CS[C@]3(C(=O)Nc4cccc(Br)c43)[C@H](c3ccc(Br)cc3)[C@H]2CN1c1ccccc1
|
C27H22Br2N2O2S 598.360000 |
DCKDRHZQEQDKGG-XYKPZGBNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260849; PubChem:CID137633279
|
Local ready
Direct docking supported
|
|
E3L050204
BDB050204
|
BDBM50260850
CCOc1ccc(N2C[C@H]3[C@@H](CS[C@]4(C(=O)Nc5cccc(Br)c54)[C@@H]3c3ccc(Br)cc3)CC2=O)cc1
|
C29H26Br2N2O3S 642.413000 |
KAWPOVNULCWTKP-XCGITAPZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260850; PubChem:CID137651753
|
Local ready
Direct docking supported
|
|
E3L050205
BDB050205
|
BDBM50260851
CCOc1cccc(N2C[C@H]3[C@@H](CS[C@]4(C(=O)Nc5cccc(Br)c54)[C@@H]3c3ccc(Br)cc3)CC2=O)c1
|
C29H26Br2N2O3S 642.413000 |
DRFNDTPXTVGQIB-XCGITAPZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260851; PubChem:CID137658457
|
Local ready
Direct docking supported
|
|
E3L050206
BDB050206
|
BDBM50260852
Cc1ccc(N2C[C@H]3[C@@H](CS[C@]4(C(=O)Nc5cccc(Br)c54)[C@@H]3c3ccc(Br)cc3)CC2=O)cc1
|
C28H24Br2N2O2S 612.387000 |
QQPACNUTQNNYIZ-ORTCJODVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260852; PubChem:CID137642942
|
Local ready
Direct docking supported
|
|
E3L050207
BDB050207
|
BDBM50260853
O=C1C[C@@H]2CS[C@]3(C(=O)Nc4cccc(Br)c43)[C@H](c3ccc(Br)cc3)[C@H]2CN1c1ccc(F)cc1F
|
C27H20Br2F2N2O2S 634.340000 |
FUMKEIBDBHOVIB-PYOZGPNLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260853; PubChem:CID137654535
|
Local ready
Direct docking supported
|
|
E3L050208
BDB050208
|
BDBM50260854
O=C1C[C@@H]2CS[C@]3(C(=O)Nc4cccc(Br)c43)[C@H](c3ccc(Br)cc3)[C@H]2CN1c1ccc(-c2ccccc2)cc1
|
C33H26Br2N2O2S 674.458000 |
BOWAKCPBWPWIPL-VMQUFCTFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260854; PubChem:CID137661225
|
Local ready
Direct docking supported
|
|
E3L050209
BDB050209
|
BDBM50260855
O=C1C[C@@H]2CS[C@]3(C(=O)Nc4cccc(Br)c43)[C@H](c3ccc(Br)cc3)[C@H]2CN1c1ccc(N2CCOCC2)cc1
|
C31H29Br2N3O3S 683.466000 |
HQZNABBEYVAOPB-IFGISIKFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260855; PubChem:CID137648244
|
Local ready
Direct docking supported
|
|
E3L050210
BDB050210
|
BDBM50260856
CCN(CC)c1ccc(N2C[C@H]3[C@@H](CS[C@]4(C(=O)Nc5cccc(Br)c54)[C@@H]3c3ccc(Br)cc3)CC2=O)cc1
|
C31H31Br2N3O2S 669.483000 |
AGCQWUOSBWAYEF-IFGISIKFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260856; PubChem:CID137657294
|
Local ready
Direct docking supported
|
|
E3L050211
BDB050211
|
BDBM50260857
O=C1Nc2cccc(Br)c2[C@@]12SC[C@@H](CCO)[C@H](CO)[C@H]2c1ccc(Br)cc1
|
C21H21Br2NO3S 527.278000 |
HOUXJXBEJBPNSS-SWQHDHIYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260857; PubChem:CID137650152
|
Local ready
Direct docking supported
|
|
E3L050212
BDB050212
|
BDBM50260858
O=C1C[C@@H]2CS[C@]3(C(=O)Nc4cccc(Br)c43)[C@H](c3ccc(Br)cc3)[C@H]2CN1c1ccccc1F
|
C27H21Br2FN2O2S 616.350000 |
ACVGMHKJMJLYGW-DTQNUGEQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260858; PubChem:CID137659486
|
Local ready
Direct docking supported
|
|
E3L050213
BDB050213
|
BDBM50260859
O=C1C[C@@H]2CS[C@]3(C(=O)Nc4cccc(Br)c43)[C@H](c3ccc(Br)cc3)[C@H]2CN1c1ccc(F)cc1
|
C27H21Br2FN2O2S 616.350000 |
UQEXEEKWERCUOR-CDOHHPMZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260859; PubChem:CID137660611
|
Local ready
Direct docking supported
|
|
E3L050214
BDB050214
|
BDBM50260860
COc1ccc(N2C[C@H]3[C@@H](CS[C@]4(C(=O)Nc5cccc(Br)c54)[C@@H]3c3ccc(Br)cc3)CC2=O)cc1
|
C28H24Br2N2O3S 628.386000 |
CINQLVZJEDMXEK-VVAOOJQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260860; PubChem:CID137631387
|
Local ready
Direct docking supported
|
|
E3L050215
BDB050215
|
BDBM50260861
CN1CCN(c2ccc(N3C[C@H]4[C@@H](CS[C@]5(C(=O)Nc6cccc(Br)c65)[C@@H]4c4ccc(Br)cc4)CC3=O)cc2)CC1
|
C32H32Br2N4O2S 696.509000 |
VTRVIEZWXXGRGT-IJIQORNZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260861; PubChem:CID137648155
|
Local ready
Direct docking supported
|
|
E3L050216
BDB050216
|
BDBM50260862
COC(=O)C[C@@H]1CS[C@]2(C(=O)Nc3cccc(Br)c32)[C@H](c2ccc(Br)cc2)[C@H]1C=O
|
C22H19Br2NO4S 553.272000 |
FUMPEDDWSGMBOW-FYVJEAPESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50260862; PubChem:CID137652653
|
Local ready
Direct docking supported
|
|
E3L050217
BDB050217
|
BDBM50261163
Cc1cccc(C(=O)N[C@H]2C[C@@H](n3cnc4c(NCc5cccc(Br)c5)ncnc43)C2)n1
|
C23H22BrN7O 492.381000 |
QYLYUTQSYHCBOD-HDICACEKSA-N | P51948 | Cyclin-H |
BindingDB
BindingDB:BDBM50261163
|
Local ready
Direct docking supported
|
|
E3L050218
BDB050218
|
BDBM50261164
Cc1cccc(C(=O)N[C@H]2C[C@@H](n3cnc4c(NCc5cccc(Cl)c5)ncnc43)C2)n1
|
C23H22ClN7O 447.930000 |
GGRVRRFOVWKWMD-HDICACEKSA-N | P51948 | Cyclin-H |
BindingDB
BindingDB:BDBM50261164
|
Local ready
Direct docking supported
|
|
E3L050219
BDB050219
|
H-Thr-Ser-Phe-Ala-Glu-Tyr-Trp-Asn-Leu-Leu-D-Thr-Pro-OH
CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)O)[C@H](C)O
|
C69H96N14O20 1441.605000 |
HWONCQFYVPJQAU-JVHWHSFSSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50261654; PubChem:CID137651436
|
Local ready
Direct docking supported
|
|
E3L050220
BDB050220
|
H-Thr-Ser-Phe-Ala-Glu-Tyr-Trp-Asn-Leu-Leu-D-Phe-Pro-OH
CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O
|
C74H98N14O19 1487.677000 |
WQEJHLGNLCVSNT-LRYQAZMXSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50261655; PubChem:CID137644501
|
Local ready
Direct docking supported
|