E3 Ligase Ligand Database

MGD and E3 ligand related compounds for browsing and docking.
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Structure similarity search Input SMILES or upload SDF/MOL/MOL2/PDB/PDBQT; results use Morgan fingerprint Tanimoto.
67228 compounds match the current filters. 123739 source records are linked to them.
Compound ID Name Formula / MW InChIKey E3 Target Source Docking structure
E3L052441
BDB052441
 BDBM50318530
[C][C@H]([N])C(=O)[N][C@@H]([C][C][C]N=C([N])[N])C(=O)[N][C@H](C(=O)N([C])[C@@H]([C][C][C][C]N([C])[C])C(=O)[N][C@@H]([C][C]C([N])=O)C(=O)[N][C@H](C(=O)[N][C@@H]([C])C(=O)[N][C@@H]([C][C][C]N=C([N])[N])C(=O)[N][C@@H]([C][C][C][C][N])C(=O)[N][C@@H]([C][O])C([N])=O)[C@@H]([C])[O])[C@@H]([C])[O]
 C49H12N20O14
1104.761000		 ZPXDUURROCDNHS-RETRBKMKSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318530
 Local ready
Direct docking supported
E3L052442
BDB052442
 BDBM50318531
CC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(N)=O)C(C)C
 C89H129N27O27
2009.173000		 UHBFDUIAGURJOH-FFCVXIFFSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318531
 Local ready
Direct docking supported
E3L052443
BDB052443
 BDBM50318532
CC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(N)=O)C(C)C
 C95H142N26O26
2064.337000		 UUCMVZMMEMCWDP-JTVDXHOOSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318532
 Local ready
Direct docking supported
E3L052444
BDB052444
 BDBM50318533
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(N)=O)C(C)C
 C90H134N24O23
1920.207000		 DUUXVEDLVMAVQN-ATJHPVBWSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318533
 Local ready
Direct docking supported
E3L052445
BDB052445
 BDBM50318534
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(N)=O)C(C)C)[C@@H](C)O
 C91H136N24O24
1950.233000		 XFKKUYQYPPAGIQ-PIHYDPKYSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318534
 Local ready
Direct docking supported
E3L052446
BDB052446
 H2N-Araevhlrks-NH2
CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O
 C49H88N20O13
1165.370000		 QSYBTXGBZPBRSE-CSNULDERSA-N P61964 WD repeat-containing protein 5
BindingDB, PubChem
BindingDB:BDBM50318535; PubChem:CID46867122
 Local ready
Direct docking supported
E3L052447
BDB052447
 BDBM50318536
[C][C@H]([N])C(=O)[N][C@@H]([C][C][C]N=C([N])[N])C(=O)[N][C@@H]([C])C([N])=O
 C12H3N7O3
293.202000		 LFTJVPCPRZKRRW-FXQIFTODSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318536
 Local ready
Direct docking supported
E3L052448
BDB052448
 BDBM50318537
[C][C@H]([N]C(=O)[C@H]([C][C][C]N=C([N])[N])[N]C(=O)[C@H]([C])[N][C]=O)C([N])=O
 C13H3N7O4
321.212000		 XRAYWAPRMDEJQL-CIUDSAMLSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318537
 Local ready
Direct docking supported
E3L052449
BDB052449
 BDBM50318538
[C]C(=O)[N][C@@H]([C])C(=O)[N][C@@H]([C][C][C]N=C([N])[N])C(=O)N([C])[C@@H]([C])C([N])=O
 C15H3N7O4
345.234000		 KOBYWYSJVYNGFG-QXEWZRGKSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318538
 Local ready
Direct docking supported
E3L052450
BDB052450
 Ac-GSARAEVHLRKS-NH2
CC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C
 C56H98N22O17
1351.537000		 PCONEFYGCDFYOM-UFBWGLHSSA-N P61964 WD repeat-containing protein 5
BindingDB, PubChem
BindingDB:BDBM50318539; PubChem:CID46889977
 Local ready
Direct docking supported
E3L052451
BDB052451
 Ac-SARAEVHLRKS-NH2
CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C
 C54H95N21O16
1294.485000		 QZWXANNPNSXHMO-RYYDISJRSA-N P61964 WD repeat-containing protein 5
BindingDB, PubChem
BindingDB:BDBM50318540; PubChem:CID46866889
 Local ready
Direct docking supported
E3L052452
BDB052452
 Ac-ARAEVHLRKS-NH2
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C
 C51H90N20O14
1207.407000		 JDETYDIWHLTWSR-BJMIAJMISA-N P61964 WD repeat-containing protein 5
BindingDB, PubChem
BindingDB:BDBM50318541; PubChem:CID46867009
 Local ready
Direct docking supported
E3L052453
BDB052453
 H2N-Saraevhlrks-NH2
CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O
 C52H93N21O15
1252.448000		 BKHVBKFFOKJNGM-PLNXYSOQSA-N P61964 WD repeat-containing protein 5
BindingDB, PubChem
BindingDB:BDBM50318542; PubChem:CID46867010
 Local ready
Direct docking supported
E3L052454
BDB052454
 Ac-RAEVHLRKS-NH2
CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C
 C48H85N19O13
1136.328000		 DBRGJMAVCWIRNI-QXZHZWOVSA-N P61964 WD repeat-containing protein 5
BindingDB, PubChem
BindingDB:BDBM50318543; PubChem:CID46867121
 Local ready
Direct docking supported
E3L052455
BDB052455
 Ac-ARAEVHL-NH2
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C
 C36H61N13O10
835.965000		 CEMFFHOCMZLMEO-IBQXPFEUSA-N P61964 WD repeat-containing protein 5
BindingDB, PubChem
BindingDB:BDBM50318544; PubChem:CID46889978
 Local ready
Direct docking supported
E3L052456
BDB052456
 Ac-ARAEVH-NH2
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C
 C30H50N12O9
722.805000		 AFTMQAFHRKDEPI-CMQAMBHRSA-N P61964 WD repeat-containing protein 5
BindingDB, PubChem
BindingDB:BDBM50318545; PubChem:CID46889979
 Local ready
Direct docking supported
E3L052457
BDB052457
 BDBM50318546
[C][C]([C])[C@H]([N]C(=O)[C@H]([C][C]C([O])=O)[N]C(=O)[C@H]([C])[N]C(=O)[C@H]([C][C][C]N=C([N])[N])[N]C(=O)[C@H]([C])[N]C([C])=O)C([N])=O
 C24H5N9O8
547.359000		 CLKJGMXTRJQIKI-XRDYDQJJSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318546
 Local ready
Direct docking supported
E3L052458
BDB052458
 BDBM50318547
[C]C(=O)[N][C@@H]([C])C(=O)[N][C@@H]([C][C][C]N=C([N])[N])C(=O)[N][C@@H]([C])C(=O)[N][C@@H]([C][C]C([O])=O)C([N])=O
 C19H4N8O7
456.290000		 TZYVMONJNIXLDJ-UKJIMTQDSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318547
 Local ready
Direct docking supported
E3L052459
BDB052459
 BDBM50318548
[C]C(=O)[N][C@@H]([C])C(=O)[N][C@@H]([C][C][C]N=C([N])[N])C(=O)[N][C@@H]([C])C([N])=O
 C14H3N7O4
333.223000		 NWDBLKWRPADFAG-NRPADANISA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318548
 Local ready
Direct docking supported
E3L052460
BDB052460
 BDBM50318549
[C]C(=O)[N][C@@H]([C])C(=O)[N][C@@H]([C][C][C]N=C([N])[N])C([N])=O
 C11H2N6O3
266.176000		 CITTYWSDHAIXIV-XPUUQOCRSA-N P61964 WD repeat-containing protein 5
BindingDB
BindingDB:BDBM50318549
 Local ready
Direct docking supported