| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L055201
BDB055201
|
BDBM50403526
COOc1cc(/C=C2\C(=O)N(c3ccccc3)N=C2C)cc(Cl)c1OCC(=O)OC
|
C21H19ClN2O6 430.844000 |
MQZLCRARJKZBGT-SXGWCWSVSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50403526; PubChem:CID171344769
|
Local ready
Direct docking supported
|
|
E3L055202
BDB055202
|
BDBM50403527
CC(C)(C)Oc1cc(C(=O)CC(N)=O)ccc1C1=N[C@@H](c2ccc(C(=O)O)cc2)[C@@H](c2c[nH]c3ccccc23)N1C(=O)N1CCNC(=O)C1
|
C36H36N6O7 664.719000 |
QSAOHHKDDGKZTL-AJQTZOPKSA-N | O15151 | Protein Mdm4 |
BindingDB
BindingDB:BDBM50403527
|
Local ready
Direct docking supported
|
|
E3L055203
BDB055203
|
BDBM50403528
C[C@@H](c1cccc(Cl)c1)n1cnc(-c2ccccc2)c1-c1c(C(=O)Nc2cc(C(=O)O)ccc2N2CCC(N3CCCOC3=O)CC2)[nH]c2cc(Cl)ccc12
|
C42H38Cl2N6O5 777.709000 |
IBRPHKCUTJQHLB-VWLOTQADSA-N | O15151 | Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50403528; PubChem:CID171353433
|
Local ready
Direct docking supported
|
|
E3L055204
BDB055204
|
BDBM50403529
C[C@@H](c1cccc(Cl)c1)n1cnc(-c2ccccc2)c1-c1c(C(=O)NCCN2CCN(C3CCCCC3)CC2)[nH]c2cc(Cl)ccc12
|
C38H42Cl2N6O 669.701000 |
UYMQKAVXRHKUHA-SANMLTNESA-N | O15151 | Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50403529; PubChem:CID171358691
|
Local ready
Direct docking supported
|
|
E3L055205
BDB055205
|
BDBM50403530
COc1cccc2c(C(=O)N[C@H]3CCN(c4ccc(C)cc4)C3)c[nH]c12
|
C21H23N3O2 349.434000 |
GMGMKERXGPBQDO-HNNXBMFYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50403530; PubChem:CID138320072
|
Local ready
Direct docking supported
|
|
E3L055206
BDB055206
|
BDBM50404375
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)C(C)(C)C)cc1
|
C57H80N8O14S2 1165.443000 |
RBXRNYWJBSBHDG-UVGSMQMLSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50404375
|
Local ready
Direct docking supported
|
|
E3L055207
BDB055207
|
BDBM50404376
CCOc1cc(C(C)(C)C)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)NCCOCCOCCOCCNC(=O)CN2CCN(C(=O)N3C(c4ccc(C(C)(C)C)cc4OCC)=N[C@H](c4ccc(Cl)cc4)[C@@H]3c3ccc(Cl)cc3)CC2=O)C(=O)C1
|
C76H88Cl4N10O11 1459.411000 |
BYXQFJDQDXLTHH-JMEZDKBESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50404376
|
Local ready
Direct docking supported
|
|
E3L055208
BDB055208
|
eTRIM24
CCCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2cccc(C(=O)NCCOCCOCCOCC(=O)N[C@@H](C(=O)N4C[C@@H](O)C[C@@H]4C(=O)NCc4ccc(-c5scnc5C)cc4)C(C)(C)C)c2)n(C)c(=O)n3C)c1
|
C55H68N8O13S2 1113.326000 |
QUQTXFIMYFMULC-RWGFKJRNSA-N | O15164 | Transcription intermediary factor 1-alpha |
BindingDB, PubChem
BindingDB:BDBM50404377; PubChem:CID131954387
|
Local ready
Direct docking supported
|
|
E3L055209
BDB055209
|
BDBM50404378
C=CC(=O)N1CCN(c2nc(NCCCN3CCN(CCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)nc3c(F)c(-c4cc(O)cc5ccccc45)c(Cl)cc23)CC1
|
C48H50ClFN10O6 917.443000 |
HIBGKXYCBQYVSE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50404378
|
Local ready
Direct docking supported
|
|
E3L055210
BDB055210
|
BDBM50404379
CCC[C@H](NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1cnc(C(=O)NCCOCCOCCOc2cc3c4c(cccc4c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)cn1)C1CCCCC1)C(C)(C)C)C(=O)C(=O)NC1CC1
|
C60H76N10O14 1161.324000 |
YZNSNVPSBDWZBQ-LNWDVATRSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50404379
|
Local ready
Direct docking supported
|
|
E3L055211
BDB055211
|
BDBM50404382
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCOc1ccc(Oc3ccc(N(Cc4ccccc4)C(=O)CCl)cc3)cc1)c1nnc(C)n1-2
|
C44H42Cl2N6O4S 821.831000 |
WSSWVTZWODGGCO-LHEWISCISA-N | P78317 | E3 ubiquitin-protein ligase RNF4 |
BindingDB
BindingDB:BDBM50404382
|
Local ready
Direct docking supported
|
|
E3L055212
BDB055212
|
HaloPROTAC3
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)c(OCCOCCOCCOCCCCCCCl)c1
|
C41H55ClN4O8S 799.431000 |
UABTZMQNIWDHGQ-JGNAJVFASA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50404384; PubChem:CID156597126
|
Local ready
Direct docking supported
|
|
E3L055213
BDB055213
|
BDBM50405190
CC(C)CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C57H80N12O9 1077.342000 |
ZOAVSRHEYNKAIW-MHNOLCRISA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50405190
|
Local ready
Direct docking supported
|
|
E3L055214
BDB055214
|
Iva-his-pro-phe-his-sta-leu-phe-NH2
CC[C@](C)(N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NC(CC(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C54H77N13O9 1052.292000 |
YLFGKFNAVPVWDW-AJEFLBOZSA-N | P00797 | Renin |
BindingDB, PubChem
BindingDB:BDBM50405191; PubChem:CID44297826
|
Local ready
Direct docking supported
|
|
E3L055215
BDB055215
|
BDBM50405192
CC(C)CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
|
C57H74N12O9 1071.294000 |
OXZWHUWYDVRMCP-MHNOLCRISA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50405192
|
Local ready
Direct docking supported
|
|
E3L055216
BDB055216
|
BDBM50405437
COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)N2CCN(C(=O)CCCNC(=O)CCCC(=O)N(CC#N)S(=O)(=O)c3ccccc3)CC2)c(OC(C)C)c1
|
C47H51Cl2N7O8S 944.939000 |
DGFDNIUVJLXQEX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50405437
|
Local ready
Direct docking supported
|
|
E3L055217
BDB055217
|
BDBM50405479
CC[C@H](C)[C@H](NC(=O)[C@@H](NC(O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)O
|
C54H80N14O11 1101.321000 |
UIOXZRLXAROYRL-UUMJJOABSA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50405479
|
Local ready
Direct docking supported
|
|
E3L055218
BDB055218
|
BDBM50405493
CC(C)CNC(=O)[C@@](O)(CN=[N+]=[N-])C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C
|
C37H57N9O7 739.919000 |
KZMPTUHLGLXWJS-HQAVLPSESA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50405493
|
Local ready
Direct docking supported
|
|
E3L055219
BDB055219
|
BDBM50405494
CC(C)CNC(=O)[C@@](O)(CCl)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C
|
C37H57ClN6O7 733.351000 |
QFNLXDJMTVIEPJ-HQAVLPSESA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50405494
|
Local ready
Direct docking supported
|
|
E3L055220
BDB055220
|
BDBM50405495
CC(C)CNC(=O)[C@@](O)(CN)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C
|
C37H59N7O7 713.921000 |
LWGNWBAQJGRCGM-HQAVLPSESA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50405495
|
Local ready
Direct docking supported
|