| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L055521
BDB055521
|
BDBM50420264
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2cc(F)c(F)cc2NC(=S)C1c1ccc(Cl)cc1
|
C24H16Cl2F2N2O3S 521.372000 |
WRYKQKGTDQVJIF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420264; PubChem:CID70684931
|
Local ready
Direct docking supported
|
|
E3L055522
BDB055522
|
BDBM50420265
COC(=O)C(c1ccc(F)cc1)N1C(=O)c2ccc(Cl)cc2NC(=S)C1c1ccc(F)cc1
|
C24H17ClF2N2O3S 486.927000 |
WHRXCDSWFWIGGJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420265; PubChem:CID70695481
|
Local ready
Direct docking supported
|
|
E3L055523
BDB055523
|
BDBM50420266
COC(=O)C(c1ccc(F)cc1)N1C(=O)c2cc(Cl)ccc2NC(=S)C1c1ccc(Cl)cc1
|
C24H17Cl2FN2O3S 503.382000 |
IIVLCPFWULYALQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420266; PubChem:CID70689181
|
Local ready
Direct docking supported
|
|
E3L055524
BDB055524
|
BDBM50420267
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2cccc(OC)c2NC(=S)C1c1ccc(Cl)cc1
|
C25H20Cl2N2O4S 515.418000 |
HNXXHZFPVSIOQQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420267; PubChem:CID70682866
|
Local ready
Direct docking supported
|
|
E3L055525
BDB055525
|
BDBM50420268
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(C(F)(F)F)cc2NC(=S)C1c1ccc(Cl)cc1
|
C25H17Cl2F3N2O3S 553.389000 |
KBEGAMLYWGDXDB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420268; PubChem:CID70687100
|
Local ready
Direct docking supported
|
|
E3L055526
BDB055526
|
BDBM50420269
COC(=O)C(c1ccc(F)cc1)N1C(=O)c2ccc(C(F)(F)F)cc2NC(=S)C1c1ccc(Cl)cc1
|
C25H17ClF4N2O3S 536.934000 |
CEJQMALQGMVVLS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420269; PubChem:CID70693378
|
Local ready
Direct docking supported
|
|
E3L055527
BDB055527
|
BDBM50420270
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(OC)cc2NC(=S)C1c1ccc(Cl)cc1
|
C25H20Cl2N2O4S 515.418000 |
SOCGYKSWZHVIGP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420270; PubChem:CID70689182
|
Local ready
Direct docking supported
|
|
E3L055528
BDB055528
|
BDBM50420271
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2cccc(C)c2NC(=S)C1c1ccc(Cl)cc1
|
C25H20Cl2N2O3S 499.419000 |
FETFMRQTYAUOQK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420271; PubChem:CID70695482
|
Local ready
Direct docking supported
|
|
E3L055529
BDB055529
|
BDBM50420272
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2cc(C)ccc2NC(=S)C1c1ccc(Cl)cc1
|
C25H20Cl2N2O3S 499.419000 |
AZLVYDXEKJXNQE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420272; PubChem:CID70697500
|
Local ready
Direct docking supported
|
|
E3L055530
BDB055530
|
BDBM50420273
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2cc(F)ccc2NC(=S)C1c1ccc(Cl)cc1
|
C24H17Cl2FN2O3S 503.382000 |
VTEPOEPLGVFUFO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420273; PubChem:CID70682867
|
Local ready
Direct docking supported
|
|
E3L055531
BDB055531
|
BDBM50420274
COC(=O)C(c1ccc(F)cc1)N1C(=O)c2ccc(F)cc2NC(=S)C1c1ccc(Cl)cc1
|
C24H17ClF2N2O3S 486.927000 |
PXPKFVPMLRMAMU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420274; PubChem:CID70693379
|
Local ready
Direct docking supported
|
|
E3L055532
BDB055532
|
BDBM50420275
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(Br)cc2NC(=S)C1c1ccc(Cl)cc1
|
C24H17BrCl2N2O3S 564.288000 |
MEGSHHRTRATOHX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420275; PubChem:CID70697501
|
Local ready
Direct docking supported
|
|
E3L055533
BDB055533
|
BDBM50420276
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(Cl)cc2NC(=S)C1c1ccc(C(F)(F)F)cc1
|
C25H17Cl2F3N2O3S 553.389000 |
NLDNWZLFIYLVPW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420276; PubChem:CID70697502
|
Local ready
Direct docking supported
|
|
E3L055534
BDB055534
|
BDBM50420277
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(Cl)cc2NC(=S)C1c1ccc(OC)cc1
|
C25H20Cl2N2O4S 515.418000 |
JYOIWJYTIQLODF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420277; PubChem:CID70682883
|
Local ready
Direct docking supported
|
|
E3L055535
BDB055535
|
BDBM50420278
CCOC(=O)CSC1=Nc2cc(OC)ccc2C(=O)N(C(C(=O)OC)c2ccc(Cl)cc2)C1c1ccc(Cl)cc1
|
C29H26Cl2N2O6S 601.508000 |
QPTHMRDIMGXPRI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420278; PubChem:CID70689192
|
Local ready
Direct docking supported
|
|
E3L055536
BDB055536
|
BDBM50420279
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(NCc3ccc(C(F)(F)F)cc3)cc2NC(=S)C1c1ccc(Cl)cc1
|
C32H24Cl2F3N3O3S 658.529000 |
GJOGVNKXCOLNRU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50420279
|
Local ready
Direct docking supported
|
|
E3L055537
BDB055537
|
BDBM50420280
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(Cl)cc2NC(=S)C1c1ccc(Cl)cc1
|
C24H17Cl3N2O3S 519.837000 |
NEXMNIQEJWBCSO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50420280; PubChem:CID70695473
|
Local ready
Direct docking supported
|
|
E3L055538
BDB055538
|
TC-Mps1-12
CC(C)(C)Nc1nc(Nc2ccc(C(N)=O)cc2)cc(N)c1C#N
|
C17H20N6O 324.388000 |
XDEFNAWAKYQBQY-UHFFFAOYSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM50420401; PubChem:CID70682875
|
Local ready
Direct docking supported
|
|
E3L055539
BDB055539
|
BDBM50420797
O=S(=O)(Nc1cc(Sc2nnc[nH]2)c(O)c2ccccc12)c1ccc2ccccc2c1
|
C22H16N4O3S2 448.529000 |
UGODIOOKONOGOI-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50420797; PubChem:CID7897116
|
Local ready
Direct docking supported
|
|
E3L055540
BDB055540
|
BDBM50421761
COC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(C)C
|
C42H63N5O10 797.991000 |
DOQMCKFDYQAPMT-RKBYHFBPSA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50421761
|
Local ready
Direct docking supported
|