| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L056541
BDB056541
|
6-Pyrrolidin-1-ylpyrrolo[2,3-b]pyridine-1-carboxamide
NC(=O)n1ccc2ccc(N3CCCC3)nc21
|
C12H14N4O 230.271000 |
ZQMRIPYRCXFVCV-UHFFFAOYSA-N | P09874 | Poly [ADP-ribose] polymerase 1 |
BindingDB, PubChem
BindingDB:BDBM50445970; PubChem:CID76335636
|
Local ready
Direct docking supported
|
|
E3L056542
BDB056542
|
Rucaparib
CNCc1ccc(-c2[nH]c3cc(F)cc4c3c2CCNC4=O)cc1
|
C19H18FN3O 323.371000 |
HMABYWSNWIZPAG-UHFFFAOYSA-N | P09874, Q92630 | Poly [ADP-ribose] polymerase 1, Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM50446130; PubChem:CID9931954
|
Local ready
Direct docking supported
|
|
E3L056543
BDB056543
|
2-(3-methyl-1,2-oxazol-5-yl)-N-propan-2-ylacetamide
Cc1cc(CC(=O)NC(C)C)on1
|
C9H14N2O2 182.223000 |
OPNVDFDZFZWBPB-UHFFFAOYSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50446132; PubChem:CID76313912
|
Local ready
Direct docking supported
|
|
E3L056544
BDB056544
|
BDBM50446133
CC(=O)NCc1ccc(-c2scnc2C)cc1
|
C13H14N2OS 246.335000 |
PLCJTEQSRQOJTH-UHFFFAOYSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50446133; PubChem:CID76324807
|
Local ready
Direct docking supported
|
|
E3L056545
BDB056545
|
(4r)-1-Acetyl-4-Hydroxy-N-Methyl-L-Prolinamide
CNC(=O)[C@@H]1C[C@@H](O)CN1C(C)=O
|
C8H14N2O3 186.211000 |
XAZYBLFYZNUKHD-RQJHMYQMSA-N | P40337, Q15369 | Elongin-C, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50446134; PubChem:CID10797632
|
Local ready
Direct docking supported
|
|
E3L056546
BDB056546
|
BDBM50446135
CNC(=O)[C@@H]1C[C@@H](O)CN1C(=O)Cc1cc(C)no1
|
C12H17N3O4 267.285000 |
RKIBNEDMQYMQFM-SCZZXKLOSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50446135; PubChem:CID57381962
|
Local ready
Direct docking supported
|
|
E3L056547
BDB056547
|
BDBM50446136
CC(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2cnco2)cc1
|
C17H19N3O4 329.356000 |
KFYARNZFJDIZMC-CABCVRRESA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50446136; PubChem:CID71819706
|
Local ready
Direct docking supported
|
|
E3L056548
BDB056548
|
BDBM50446137
CC(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C18H21N3O3S 359.451000 |
NKCKHEUZJVZXJO-CVEARBPZSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50446137; PubChem:CID76332034
|
Local ready
Direct docking supported
|
|
E3L056549
BDB056549
|
BDBM50446138
Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3cnco3)cc2)on1
|
C21H22N4O5 410.430000 |
HFCLIEBJTGJKSV-AEFFLSMTSA-N | P40337, Q15369 | Elongin-C, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50446138; PubChem:CID56684144
|
Local ready
Direct docking supported
|
|
E3L056550
BDB056550
|
BDBM50446139
Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)on1
|
C22H24N4O4S 440.525000 |
FEFYMYQFVDBQAU-MJGOQNOKSA-N | P40337, P62877, Q13617, Q15369 | von Hippel-Lindau disease tumor suppressor, Cullin-2, Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50446139; PubChem:CID71608571
|
Local ready
Direct docking supported
|
|
E3L056551
BDB056551
|
BDBM50446192
COc1cc(C(N)=O)ccc1NC(=O)[C@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)sc32)[C@@H]1c1cccc(Cl)c1F
|
C29H29Cl2FN4O4S 619.546000 |
UOVSZRTTWLJPHE-RPMQLHGRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446192
|
Local ready
Direct docking supported
|
|
E3L056552
BDB056552
|
BDBM50446193
COc1cc(C(=O)O)ccc1NC(=O)[C@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)sc32)[C@@H]1c1cccc(Cl)c1F
|
C29H28Cl2FN3O5S 620.530000 |
YXQHJKFKRZDXHV-RPMQLHGRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446193
|
Local ready
Direct docking supported
|
|
E3L056553
BDB056553
|
BDBM50446194
COc1cc(C(N)=O)ccc1NC(=O)[C@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)ncc32)[C@@H]1c1cccc(Cl)c1F
|
C30H30Cl2FN5O4 614.505000 |
CGCOPBXAGSCZNX-JLEYQQFFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446194
|
Local ready
Direct docking supported
|
|
E3L056554
BDB056554
|
BDBM50446195
COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)sc32)[C@H]1c1cccc(Cl)c1F
|
C29H29Cl2FN4O4S 619.546000 |
UOVSZRTTWLJPHE-HNXAPSNLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446195
|
Local ready
Direct docking supported
|
|
E3L056555
BDB056555
|
BDBM50446196
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)sc32)[C@H]1c1cccc(Cl)c1F
|
C29H28Cl2FN3O5S 620.530000 |
YXQHJKFKRZDXHV-HNXAPSNLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446196
|
Local ready
Direct docking supported
|
|
E3L056556
BDB056556
|
BDBM50446197
COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
|
C30H30Cl2FN5O4 614.505000 |
CGCOPBXAGSCZNX-FNQJWKMRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446197
|
Local ready
Direct docking supported
|
|
E3L056557
BDB056557
|
BDBM50446198
COc1cc(C(N)=O)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3cc(Cl)sc32)C1c1cccc(Cl)c1F
|
C29H29Cl2FN4O4S 619.546000 |
UOVSZRTTWLJPHE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446198
|
Local ready
Direct docking supported
|
|
E3L056558
BDB056558
|
BDBM50446199
COc1cc(C(=O)O)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3cc(Cl)sc32)C1c1cccc(Cl)c1F
|
C29H28Cl2FN3O5S 620.530000 |
YXQHJKFKRZDXHV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50446199; PubChem:CID76328371
|
Local ready
Direct docking supported
|
|
E3L056559
BDB056559
|
BDBM50446200
COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3nc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
|
C29H29Cl2FN6O4 615.493000 |
ORCGOHBRBKYLAQ-ROUDKJGJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446200
|
Local ready
Direct docking supported
|
|
E3L056560
BDB056560
|
BDBM50446201
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3nc(Cl)ncc32)[C@H]1c1cccc(Cl)c1F
|
C29H28Cl2FN5O5 616.477000 |
JMUOXYBXFJQWPT-ROUDKJGJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50446201
|
Local ready
Direct docking supported
|