| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L056661
BDB056661
|
BDBM50448964
CC(C)(C)[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C30H39Cl2NO5S 596.617000 |
PRPDXHXTFJYCMK-JVUUKAHWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448964; PubChem:CID76310907
|
Local ready
Direct docking supported
|
|
E3L056662
BDB056662
|
BDBM50448965
CC(C)[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H37Cl2NO5S 582.590000 |
CGHHPXBKIIKZHJ-HIJQLYNKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448965; PubChem:CID68000797
|
Local ready
Direct docking supported
|
|
E3L056663
BDB056663
|
BDBM50448966
C[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H33Cl2NO5S 554.536000 |
UWRLSPZJOFEMKC-RRUUKPGGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448966; PubChem:CID76328992
|
Local ready
Direct docking supported
|
|
E3L056664
BDB056664
|
BDBM50448967
CC(C)(C)S(=O)(=O)C[C@H](CC(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H32Cl2F3NO5S 622.533000 |
UXTMCOJFIVJBRG-CXTNQITHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448967; PubChem:CID76321813
|
Local ready
Direct docking supported
|
|
E3L056665
BDB056665
|
BDBM50448968
CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H34Cl2N2O5S 581.562000 |
VGFHAVBKPIGMLJ-NUWWLQTNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448968; PubChem:CID67999393
|
Local ready
Direct docking supported
|
|
E3L056666
BDB056666
|
BDBM50448969
CN(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1)S(=O)(=O)C1CC1
|
C29H34Cl2N2O5S 593.573000 |
GNBHDBPUJCJXQG-GCMXZSHTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448969; PubChem:CID58573621
|
Local ready
Direct docking supported
|
|
E3L056667
BDB056667
|
BDBM50448970
CC(C)[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H36Cl2N2O5S 595.589000 |
NAOFRLUOVJQSJF-GCMXZSHTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448970; PubChem:CID67999477
|
Local ready
Direct docking supported
|
|
E3L056668
BDB056668
|
BDBM50448971
CC[C@@H](CNS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H32Cl2N2O5S 567.535000 |
YGHOMOFTRXHIOD-OCBXDECUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448971; PubChem:CID58573255
|
Local ready
Direct docking supported
|
|
E3L056669
BDB056669
|
BDBM50448972
CC[C@@H](CN(C)S(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H38Cl2N2O5S 597.605000 |
DSXCZCSHMQWYGJ-NANZAVOOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50448972; PubChem:CID58573852
|
Local ready
Direct docking supported
|
|
E3L056670
BDB056670
|
BDBM50449313
COc1cc(OC)c(/C=C/C(=O)c2c(O)cccc2OC)c(OC)c1
|
C19H20O6 344.363000 |
UONXTKVFIVPLHR-CMDGGOBGSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM50449313; PubChem:CID71554422
|
Local ready
Direct docking supported
|
|
E3L056671
BDB056671
|
BDBM50449894
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCC(Nc2ncc(C(=O)NO)cn2)CC1
|
C38H41Cl2N7O4 730.697000 |
ROEDEHJYQJQQNG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449894; PubChem:CID145959742
|
Local ready
Direct docking supported
|
|
E3L056672
BDB056672
|
BDBM50449895
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCCCCCC(=O)NO)CC1
|
C40H51Cl2N5O4 736.785000 |
KCNXPULEWIDILM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449895; PubChem:CID145949513
|
Local ready
Direct docking supported
|
|
E3L056673
BDB056673
|
BDBM50449896
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCCCC(=O)NO)CC1
|
C38H47Cl2N5O4 708.731000 |
IVBGBXGOIUKKTI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449896; PubChem:CID145957798
|
Local ready
Direct docking supported
|
|
E3L056674
BDB056674
|
BDBM50449897
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCCCCC(=O)NO
|
C36H44Cl2N4O4 667.678000 |
YNXQVNCAJRXSAG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449897; PubChem:CID145958259
|
Local ready
Direct docking supported
|
|
E3L056675
BDB056675
|
BDBM50449898
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCC(=O)NO
|
C33H38Cl2N4O4 625.597000 |
OJIFXIMEUNDVIC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449898; PubChem:CID145952910
|
Local ready
Direct docking supported
|
|
E3L056676
BDB056676
|
BDBM50449899
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCC(=O)Nc1ccccc1N
|
C39H43Cl2N5O3 700.711000 |
HLRSMWOUOQSYFC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449899; PubChem:CID145951496
|
Local ready
Direct docking supported
|
|
E3L056677
BDB056677
|
BDBM50449900
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCCCCC(=O)NO)CC1
|
C39H49Cl2N5O4 722.758000 |
ODMAGXZOJNLPBL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449900; PubChem:CID138393072
|
Local ready
Direct docking supported
|
|
E3L056678
BDB056678
|
BDBM50449901
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)NO)CC1
|
C34H39Cl2N5O4 652.623000 |
WHVPVWOHWOTPPU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449901; PubChem:CID145957183
|
Local ready
Direct docking supported
|
|
E3L056679
BDB056679
|
BDBM50449902
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCc1ccc(C(=O)NO)cc1
|
C36H36Cl2N4O4 659.614000 |
GOUONROMMLUDGC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449902; PubChem:CID145949937
|
Local ready
Direct docking supported
|
|
E3L056680
BDB056680
|
BDBM50449903
CCOc1cc(C(C)(C)C)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)NCCCCCC(=O)NO
|
C34H40Cl2N4O4 639.624000 |
KVFSTCKKMSWEHH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50449903; PubChem:CID145956323
|
Local ready
Direct docking supported
|