| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L056981
BDB056981
|
BDBM50459879
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCNC(=O)C[C@@H]2N=C(c3ccc(Cl)cc3)c3c(sc(C)c3C)-n3c(C)nnc32)C(C)(C)C)cc1
|
C51H64ClN9O9S2 1046.714000 |
LSELSHXLKGXPPF-BOBBFQORSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50459879
|
Local ready
Direct docking supported
|
|
E3L056982
BDB056982
|
BDBM50459880
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCNC(=O)C[C@@H]2N=C(c3ccc(Cl)cc3)c3c(sc(C)c3C)-n3c(C)nnc32)C(C)(C)C)cc1
|
C49H60ClN9O8S2 1002.661000 |
PTAMRJLIOCHJMQ-PYNGZGNASA-N | P40337, Q15369 | Elongin-C, von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50459880
|
Local ready
Direct docking supported
|
|
E3L056983
BDB056983
|
BDBM50459881
CC(=O)N1c2ccc(-c3ccc(C(=O)NCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N4C[C@H](O)C[C@H]4C(=O)NCc4ccc(-c5scnc5C)cc4)C(C)(C)C)cc3)cc2[C@H](Nc2ccc(Cl)cc2)C[C@@H]1C
|
C57H70ClN7O10S 1080.746000 |
UHWNJFZTYJNBAN-HYXXSBGTSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50459881
|
Local ready
Direct docking supported
|
|
E3L056984
BDB056984
|
BDBM50459896
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCCOCCCCOCCCOc2ccc(Nc3ncc(C4CC4)c(NCCCN(C)C(=O)C4CCC4)n3)cc2)C(C)(C)C)cc1
|
C56H79N9O9S 1054.369000 |
BBLUCKCGFGRHBM-PNADFZFASA-N | P40337, Q15369, Q15370 | Hypoxia-inducible factor 1-alpha |
BindingDB
BindingDB:BDBM50459896
|
Local ready
Direct docking supported
|
|
E3L056985
BDB056985
|
TBK1 PROTAC 3i
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCCOCCCCOCCCOc2ccc(Nc3ncc(Br)c(NCCCN(C)C(=O)C4CCC4)n3)cc2)C(C)(C)C)cc1
|
C53H74BrN9O9S 1093.200000 |
QMGHHBHPDDAGGO-IIWOMYBWSA-N | P40337, Q15369, Q15370 | Hypoxia-inducible factor 1-alpha |
BindingDB, PubChem
BindingDB:BDBM50459898; PubChem:CID124108661
|
Local ready
Direct docking supported
|
|
E3L056986
BDB056986
|
BDBM50459899
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C)NC(=O)COCCCOCCCCOCCCOc2ccc(Nc3ncc(Br)c(NCCCN(C)C(=O)C4CCC4)n3)cc2)cc1
|
C50H68BrN9O9S 1051.119000 |
SKNABLAZUJHUQD-XPNGYUDYSA-N | P40337, Q15369, Q15370 | Hypoxia-inducible factor 1-alpha |
BindingDB
BindingDB:BDBM50459899
|
Local ready
Direct docking supported
|
|
E3L056987
BDB056987
|
BDBM50459905
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)CNC(=O)COCCCOCCCCOCCCOc2ccc(Nc3ncc(Br)c(NCCCN(C)C(=O)C4CCC4)n3)cc2)cc1
|
C49H66BrN9O9S 1037.092000 |
RHMRGNADRCTXDD-QHIUNZLJSA-N | P40337, Q15369, Q15370 | Hypoxia-inducible factor 1-alpha |
BindingDB
BindingDB:BDBM50459905
|
Local ready
Direct docking supported
|
|
E3L056988
BDB056988
|
BDBM50459906
CCC[C@H](NC(=O)COCCCOCCCCOCCCOc1ccc(Nc2ncc(Br)c(NCCCN(C)C(=O)C3CCC3)n2)cc1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C52H72BrN9O9S 1079.173000 |
RMEVTEIDHGHTFH-AFCPVBLQSA-N | P40337, Q15369, Q15370 | Hypoxia-inducible factor 1-alpha |
BindingDB
BindingDB:BDBM50459906
|
Local ready
Direct docking supported
|
|
E3L056989
BDB056989
|
BDBM50459907
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCCOCCCCOCCCOc2ccc(Nc3ncc(Br)c(NCCCN(C)C(=O)C4CCC4)n3)cc2)C(C)C)cc1
|
C52H72BrN9O9S 1079.173000 |
BVZVRIHXPPJLEK-RPBINQBJSA-N | P40337, Q15369, Q15370 | Hypoxia-inducible factor 1-alpha |
BindingDB
BindingDB:BDBM50459907
|
Local ready
Direct docking supported
|
|
E3L056990
BDB056990
|
BDBM50459909
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H](NC(=O)COCCCOCCCCOCCCOc2ccc(Nc3ncc(Br)c(NCCCN(C)C(=O)C4CCC4)n3)cc2)C(C)(C)C)cc1
|
C53H74BrN9O9S 1093.200000 |
QMGHHBHPDDAGGO-JTTRWUFTSA-N | P40337, Q15369, Q15370 | Hypoxia-inducible factor 1-alpha |
BindingDB
BindingDB:BDBM50459909
|
Local ready
Direct docking supported
|
|
E3L056991
BDB056991
|
BDBM50459913
CC[C@H](NC(=O)COCCCOCCCCOCCCOc1ccc(Nc2ncc(Br)c(NCCCN(C)C(=O)C3CCC3)n2)cc1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C51H70BrN9O9S 1065.146000 |
PAVSYJSRMMUDDB-ANXVSDTMSA-N | P40337, Q15369, Q15370 | Hypoxia-inducible factor 1-alpha |
BindingDB
BindingDB:BDBM50459913
|
Local ready
Direct docking supported
|
|
E3L056992
BDB056992
|
BDBM50459942
CC(=O)N[C@@H](C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C21H26N4O4S 430.530000 |
JKHAXURJIZDRKK-VHSSKADRSA-N | P40337, P62877, Q13617, Q15369 | Cullin-2, von Hippel-Lindau disease tumor suppressor, Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50459942; PubChem:CID72734456
|
Local ready
Direct docking supported
|
|
E3L056993
BDB056993
|
BDBM50459945
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CCC2)C(C)(C)C)cc1
|
C27H36N4O4S 512.676000 |
DKNMIOWXDLCWDG-FUPPJEDESA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50459945
|
Local ready
Direct docking supported
|
|
E3L056994
BDB056994
|
(S,R,S)-AHPC-Boc
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)cc1
|
C27H38N4O5S 530.691000 |
PKNFPFFOAWITLF-RZUBCFFCSA-N | Q15369 | Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50459946; PubChem:CID117727555
|
Local ready
Direct docking supported
|
|
E3L056995
BDB056995
|
(S,R,S)-Ahpc-CO-C1-OH
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CO)C(C)(C)C)cc1
|
C24H32N4O5S 488.610000 |
OFCMFZVSIVJIET-LVCYWYKZSA-N | Q15369 | Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50459947; PubChem:CID129900321
|
Local ready
Direct docking supported
|
|
E3L056996
BDB056996
|
BDBM50459948
CCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C
|
C25H34N4O4S 486.638000 |
DAQZMDAVCMVVFQ-XQBPLPMBSA-N | P40337, P62877, Q13617, Q15369 | Cullin-2, von Hippel-Lindau disease tumor suppressor, Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50459948; PubChem:CID122528991
|
Local ready
Direct docking supported
|
|
E3L056997
BDB056997
|
BDBM50459949
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CC2)C(C)(C)C)cc1
|
C26H34N4O4S 498.649000 |
TXHVAXXHWXOMKR-RZUBCFFCSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50459949
|
Local ready
Direct docking supported
|
|
E3L056998
BDB056998
|
Tfa-Gly(tBu)-Hyp-Unk
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C(F)(F)F)C(C)(C)C)cc1
|
C24H29F3N4O4S 526.581000 |
LDFHQQVQPPLUDX-ZIFCJYIRSA-N | Q15369 | Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50459950; PubChem:CID145986800
|
Local ready
Direct docking supported
|
|
E3L056999
BDB056999
|
BDBM50459951
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C(C)(C)F)C(C)(C)C)cc1
|
C26H35FN4O4S 518.655000 |
QZNQKYSTRCIAKT-SVFBPWRDSA-N | Q15369 | Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50459951; PubChem:CID145986595
|
Local ready
Direct docking supported
|
|
E3L057000
BDB057000
|
BDBM50459952
CC(=O)N(C)[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C
|
C25H34N4O4S 486.638000 |
IIPLOHQVELTIPV-RZUBCFFCSA-N | P40337, P62877, Q13617, Q15369 | Cullin-2, Elongin-C, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50459952; PubChem:CID122528924
|
Local ready
Direct docking supported
|