| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L057981
BDB057981
|
BDBM50500358
CCc1cc2c(cc1-c1cn[nH]c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
|
C24H20N4O 380.451000 |
BUHLWVQDHMLTPT-UHFFFAOYSA-N | Q9HC35 | ALK tyrosine kinase receptor |
BindingDB, PubChem
BindingDB:BDBM50500358; PubChem:CID127042588
|
Local ready
Direct docking supported
|
|
E3L057982
BDB057982
|
BDBM50500359
CCc1cc2c(cc1-c1cnn[nH]1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
|
C23H19N5O 381.439000 |
QKYONSSKLFQUAK-UHFFFAOYSA-N | Q9HC35 | ALK tyrosine kinase receptor |
BindingDB, PubChem
BindingDB:BDBM50500359; PubChem:CID127040272
|
Local ready
Direct docking supported
|
|
E3L057983
BDB057983
|
BDBM50500360
CCc1cc2c(cc1-c1cc[nH]n1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
|
C24H20N4O 380.451000 |
JINIKYUAUCGQAS-UHFFFAOYSA-N | Q9HC35 | ALK tyrosine kinase receptor |
BindingDB, PubChem
BindingDB:BDBM50500360; PubChem:CID127041847
|
Local ready
Direct docking supported
|
|
E3L057984
BDB057984
|
BDBM50500856
CC(C)Oc1ccc(C(=O)Nc2c(C(=O)O)nn(-c3ccc(C(C)C)cc3)c2-c2ccc(OCc3ccccc3)cc2)cc1
|
C36H35N3O5 589.692000 |
CLACLESTZWRFRK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500856; PubChem:CID127046868
|
Local ready
Direct docking supported
|
|
E3L057985
BDB057985
|
BDBM50500857
CC(C)Oc1ccc(-c2cc(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
|
C25H22N2O4 414.461000 |
YMZIQERIFKUTOB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500857; PubChem:CID127047006
|
Local ready
Direct docking supported
|
|
E3L057986
BDB057986
|
BDBM50500858
CCOc1ccc(-c2cc(C(=O)O)nn2-c2ccccc2)cc1
|
C18H16N2O3 308.337000 |
QHXBYJRUEXSIEL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500858; PubChem:CID2771353
|
Local ready
Direct docking supported
|
|
E3L057987
BDB057987
|
BDBM50500859
CC(C)COc1ccc(C(=O)Nc2c(C(=O)O)nn(-c3ccc(Oc4ccccc4)cc3)c2-c2ccc(OC(C)C)cc2)cc1
|
C36H35N3O6 605.691000 |
YFJFMRRMGIOCHI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500859; PubChem:CID127046716
|
Local ready
Direct docking supported
|
|
E3L057988
BDB057988
|
BDBM50500860
CC(C)Oc1ccc(C(=O)Nc2c(C(=O)O)nn(-c3ccc(Oc4ccccc4)cc3)c2-c2ccc(OC(C)C)cc2)cc1
|
C35H33N3O6 591.664000 |
XMMSWQSSUYVMCR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500860; PubChem:CID127045927
|
Local ready
Direct docking supported
|
|
E3L057989
BDB057989
|
BDBM50500861
CCOc1ccc(-c2c(NC(=O)c3ccc(OC(C)C)cc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
|
C34H31N3O6 577.637000 |
YGMNUAIEAAWEDE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500861; PubChem:CID127045715
|
Local ready
Direct docking supported
|
|
E3L057990
BDB057990
|
BDBM50500862
CC(C)Oc1ccc(-c2cc(C(=O)O)nn2-c2ccc(C(C)C)cc2)cc1
|
C22H24N2O3 364.445000 |
DMCZSKBVBDIGON-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500862; PubChem:CID127047007
|
Local ready
Direct docking supported
|
|
E3L057991
BDB057991
|
BDBM50500863
CCOc1ccc(-c2c(NC(=O)c3ccc(OCC(C)C)cc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
|
C35H33N3O6 591.664000 |
BRWCOCICLLQFLI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500863; PubChem:CID127045716
|
Local ready
Direct docking supported
|
|
E3L057992
BDB057992
|
BDBM50500864
COC(=O)c1nn(-c2ccc(Oc3ccccc3)cc2)c(-c2ccc(OC(C)C)cc2)c1NC(=O)c1ccc(OC(C)C)cc1
|
C36H35N3O6 605.691000 |
DYUSLCVTUPNKTB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500864; PubChem:CID127046869
|
Local ready
Direct docking supported
|
|
E3L057993
BDB057993
|
BDBM50500865
CCOc1ccc(-c2c(NC(=O)c3ccccc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
|
C31H25N3O5 519.557000 |
OMNHLSACIDVOIX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500865; PubChem:CID127045713
|
Local ready
Direct docking supported
|
|
E3L057994
BDB057994
|
BDBM50500866
CC(C)c1ccc(-n2nc(C(=O)O)cc2-c2ccc(OCc3ccccc3)cc2)cc1
|
C26H24N2O3 412.489000 |
UENGMGNNNAYDNG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500866; PubChem:CID127047008
|
Local ready
Direct docking supported
|
|
E3L057995
BDB057995
|
BDBM50500867
CCOc1ccc(-c2c(NC(=O)c3ccc(C(C)(C)C)cc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
|
C35H33N3O5 575.665000 |
ZVNNFQPPAUZMTQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500867; PubChem:CID127045714
|
Local ready
Direct docking supported
|
|
E3L057996
BDB057996
|
BDBM50500868
CCOc1ccc(-c2cc(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1
|
C24H20N2O4 400.434000 |
GRDDGUBYUUVVGI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500868; PubChem:CID127047005
|
Local ready
Direct docking supported
|
|
E3L057997
BDB057997
|
BDBM50500869
O=C(O)c1cc(-c2ccc(OCc3ccccc3)cc2)n(-c2ccccc2)n1
|
C23H18N2O3 370.408000 |
YVEDDGSEZADRSQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500869; PubChem:CID127047004
|
Local ready
Direct docking supported
|
|
E3L057998
BDB057998
|
BDBM50500870
CC(C)COc1ccc(-c2cc(C(=O)O)nn2-c2ccccc2)cc1
|
C20H20N2O3 336.391000 |
KAOKRVGFJLGJRV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500870; PubChem:CID127047003
|
Local ready
Direct docking supported
|
|
E3L057999
BDB057999
|
BDBM50500871
CC(C)Oc1ccc(-c2cc(C(=O)O)nn2-c2ccccc2)cc1
|
C19H18N2O3 322.364000 |
UKGNVPWMQUQOGC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500871; PubChem:CID94962278
|
Local ready
Direct docking supported
|
|
E3L058000
BDB058000
|
BDBM50500872
CC(C)Oc1ccc(C(=O)Nc2c(C(=O)O)nn(-c3ccc(Oc4ccccc4)cc3)c2-c2ccc(OCc3ccccc3)cc2)cc1
|
C39H33N3O6 639.708000 |
AEJNGYMCEFEGCG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50500872; PubChem:CID127046867
|
Local ready
Direct docking supported
|