| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L061301
BDB061301
|
CREBBP/EP300 inhibitor (-)-OXFBD05
COc1ccc2c(c1)N(CCC/C=C/c1cccc3c1N[C@@H](C)CC(=O)N3)CCC2
|
C25H31N3O2 405.542000 |
VBTDHMQUNCGCSZ-PYJQOMOHSA-N | Q09472, Q92793 | Histone acetyltransferase p300, CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50579718; PubChem:CID166630089
|
Local ready
Direct docking supported
|
|
E3L061302
BDB061302
|
BDBM50579719
COc1cc(N2CCN(CCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(-c4scnc4C)cc3)C(C)(C)C)CC2)ccc1NC(=O)c1cccc(-c2cc[nH]n2)n1
|
C45H54N10O6S 863.058000 |
WAOZMJFYNREQLU-MJWYEJTISA-N | P40337, P51617 | von Hippel-Lindau disease tumor suppressor, Interleukin-1 receptor-associated kinase 1 |
BindingDB
BindingDB:BDBM50579719
|
Local ready
Direct docking supported
|
|
E3L061303
BDB061303
|
BDBM50579720
COc1cc(N2CCC(OCC(=O)N[C@H](C(=O)N3C[C@@H](O)C[C@H]3C(=O)N[C@@H](C)c3ccc(-c4scnc4C)cc3)C(C)(C)C)CC2)ccc1NC(=O)c1cccc(-c2ccn[nH]2)n1
|
C46H55N9O7S 878.069000 |
MHRNVFQJUUXQIG-LZJKKMSRSA-N | P40337, P51617 | Interleukin-1 receptor-associated kinase 1, von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50579720
|
Local ready
Direct docking supported
|
|
E3L061304
BDB061304
|
BDBM50579721
COc1cc(N2CCC(OCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(-c4scnc4C)cc3)C(C)(C)C)CC2)ccc1NC(=O)c1cccc(-c2ccn[nH]2)n1
|
C45H53N9O7S 864.042000 |
PWCLOPMRUGHLET-SPVIJIGUSA-N | P40337, P51617 | Interleukin-1 receptor-associated kinase 1, von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50579721
|
Local ready
Direct docking supported
|
|
E3L061305
BDB061305
|
BDBM50579722
COc1cc(N2CCC(OCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N[C@@H](C)c3ccc(-c4scnc4C)cc3)C(C)(C)C)CC2)ccc1NC(=O)c1cccc(-c2ccn[nH]2)n1
|
C46H55N9O7S 878.069000 |
MHRNVFQJUUXQIG-VIFUUBRESA-N | P40337, P51617 | Interleukin-1 receptor-associated kinase 1, von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50579722
|
Local ready
Direct docking supported
|
|
E3L061306
BDB061306
|
BDBM50579787
Cc1ccc(N2CCN(Cc3ccc(-c4cccc(C(=O)O)c4)o3)C2=O)cc1C
|
C23H22N2O4 390.439000 |
WGZLBTNXAHGTKQ-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579787; PubChem:CID166633047
|
Local ready
Direct docking supported
|
|
E3L061307
BDB061307
|
BDBM50579788
Cc1ccc(N2CC(=O)C(Cc3ccc(-c4cccc(C(=O)O)c4)o3)C2=O)cc1C
|
C24H21NO5 403.434000 |
LFRRTLXVNCPAOG-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579788; PubChem:CID166629484
|
Local ready
Direct docking supported
|
|
E3L061308
BDB061308
|
BDBM50579789
Cc1ccc(N2CC(=O)N(Cc3ccc(-c4cccc(C(=O)O)c4)o3)C2=O)cc1C
|
C23H20N2O5 404.422000 |
DSDHEBGHCWJLQM-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579789; PubChem:CID166632208
|
Local ready
Direct docking supported
|
|
E3L061309
BDB061309
|
BDBM50579790
Cc1ccc(N2C(=O)CN(Cc3ccc(-c4cccc(C(=O)O)c4)o3)C2=O)cc1C
|
C23H20N2O5 404.422000 |
IOGDCCAIPMFDBX-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579790; PubChem:CID166633318
|
Local ready
Direct docking supported
|
|
E3L061310
BDB061310
|
BDBM50579791
Cc1ccc(N2CC(C)N(Cc3ccc(-c4cccc(C(=O)O)c4)o3)C2=O)cc1C
|
C24H24N2O4 404.466000 |
URDWJXMUHRTJIU-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579791; PubChem:CID166625806
|
Local ready
Direct docking supported
|
|
E3L061311
BDB061311
|
BDBM50579792
COC1=C(Cc2ccc(-c3cccc(C(=O)O)c3)o2)C(=O)N(c2ccc(C)c(C)c2)C1
|
C25H23NO5 417.461000 |
YMXXLCAOLPPTSX-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579792; PubChem:CID166634239
|
Local ready
Direct docking supported
|
|
E3L061312
BDB061312
|
BDBM50579793
CC1=NN(c2cccc(Cl)c2)C(=O)/C1=C/c1ccc(-c2ccc(Cl)c(C(=O)O)c2)o1
|
C22H14Cl2N2O4 441.270000 |
VWXSRBJMGWTPIA-GZTJUZNOSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579793; PubChem:CID5342377
|
Local ready
Direct docking supported
|
|
E3L061313
BDB061313
|
BDBM50579794
O=C(O)c1cccc(-c2ccc(CN3CCN(c4ccc5ccccc5c4)C3=O)o2)c1
|
C25H20N2O4 412.445000 |
QNCJLRPMBRJWGS-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579794; PubChem:CID166635948
|
Local ready
Direct docking supported
|
|
E3L061314
BDB061314
|
BDBM50579795
Cc1ccc(N2CCN(Cc3ccc(-c4cccc(C(=O)O)c4)s3)C2=O)cc1C
|
C23H22N2O3S 406.507000 |
YCLMACVFXROKKV-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579795; PubChem:CID166634001
|
Local ready
Direct docking supported
|
|
E3L061315
BDB061315
|
BDBM50579796
COC1=C(Cc2ccc(-c3cccc(C(=O)O)c3)s2)C(=O)N(c2ccc3ccccc3c2)C1
|
C27H21NO4S 455.535000 |
XWDMKSIUCITTML-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579796; PubChem:CID166635304
|
Local ready
Direct docking supported
|
|
E3L061316
BDB061316
|
BDBM50579797
COC1=C(Cc2ccc(-c3cncc(C(=O)O)c3)s2)C(=O)N(c2ccc3ccccc3c2)C1
|
C26H20N2O4S 456.523000 |
OMUMJFLFMDCGPF-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579797; PubChem:CID166630962
|
Local ready
Direct docking supported
|
|
E3L061317
BDB061317
|
BDBM50579798
COC1=C(Cc2ccc(-c3cn(C)cc(C(=O)O)c3=O)s2)C(=O)N(c2ccc3ccccc3c2)C1
|
C27H22N2O5S 486.549000 |
ZIPDAVWUASGEPT-UHFFFAOYSA-N | Q09472, Q92793, Q92831 | Histone acetyltransferase KAT2B, Histone acetyltransferase p300, CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50579798; PubChem:CID166628788
|
Local ready
Direct docking supported
|
|
E3L061318
BDB061318
|
BDBM50579799
CCn1cc(C(=O)O)c(=O)c(-c2ccc(CC3=C(OC)CN(c4ccc5ccccc5c4)C3=O)s2)c1
|
C28H24N2O5S 500.576000 |
OMBLNAUCEYVJHL-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579799; PubChem:CID166634754
|
Local ready
Direct docking supported
|
|
E3L061319
BDB061319
|
BDBM50579800
COC1=C(Cc2ccc(-c3cn(C(C)C)cc(C(=O)O)c3=O)s2)C(=O)N(c2ccc3ccccc3c2)C1
|
C29H26N2O5S 514.603000 |
SZHZVUFFCBSXHL-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50579800; PubChem:CID166627462
|
Local ready
Direct docking supported
|
|
E3L061320
BDB061320
|
BDBM50579801
COC1=C(Cc2ccc(-c3cn(Cc4ccccc4)cc(C(=O)O)c3=O)s2)C(=O)N(c2ccc3ccccc3c2)C1
|
C33H26N2O5S 562.647000 |
YIGVZXFIAKXNEU-UHFFFAOYSA-N | Q09472, Q92793, Q92831 | Histone acetyltransferase KAT2B, Histone acetyltransferase p300, CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50579801; PubChem:CID166634994
|
Local ready
Direct docking supported
|