| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L061941
BDB061941
|
BDBM50590278
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N2C[C@@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)C(C)(C)C)cc1
|
C56H78N8O13S2 1135.417000 |
GXUKQNHVGSQLDF-PFLUJNLJSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50590278
|
Local ready
Direct docking supported
|
|
E3L061942
BDB061942
|
Homo-PROTAC pVHL30 degrader 1
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)C(C)(C)C)cc1
|
C58H82N8O14S2 1179.470000 |
WGJCHHJGGFCCRS-DEYDLUNASA-N | Q15369 | Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50590279; PubChem:CID134160242
|
Local ready
Direct docking supported
|
|
E3L061943
BDB061943
|
BDBM50590280
O=C(NCc1ccc(Br)cc1)[C@@H]1C[C@@H](O)CN1C(=O)CC(F)(F)F
|
C15H16BrF3N2O3 409.202000 |
HZXVIHSWGKQYTM-NEPJUHHUSA-N | Q15369 | Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50590280; PubChem:CID168276187
|
Local ready
Direct docking supported
|
|
E3L061944
BDB061944
|
BDBM50590281
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)CC(C)(C)C)cc1C(F)(F)F
|
C23H28F3N3O3S 483.556000 |
ZANQYVSMGGHBCW-QAPCUYQASA-N | Q15369 | Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50590281; PubChem:CID167739202
|
Local ready
Direct docking supported
|
|
E3L061945
BDB061945
|
BDBM50590282
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)C(F)(F)F)cc1
|
C18H18F3N3O3S 413.421000 |
YZPLZOZNVWZFST-KGLIPLIRSA-N | Q15369 | Elongin-C |
BindingDB, PubChem
BindingDB:BDBM50590282; PubChem:CID167719023
|
Local ready
Direct docking supported
|
|
E3L061946
BDB061946
|
BDBM50590283
N#CN1CC[C@H](C(=O)Nc2ncc(-c3ccccc3)s2)C1
|
C15H14N4OS 298.371000 |
DPOQOSJMDTZFOR-LBPRGKRZSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM50590283; PubChem:CID118980596
|
Local ready
Direct docking supported
|
|
E3L061947
BDB061947
|
BDBM50590284
C#Cc1ccc(-c2cnc(NC(=O)[C@H]3CCN(C#N)C3)s2)cc1
|
C17H14N4OS 322.393000 |
ICEKJWVSDFOADH-AWEZNQCLSA-N | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
BindingDB, PubChem
BindingDB:BDBM50590284; PubChem:CID118981108
|
Local ready
Direct docking supported
|
|
E3L061948
BDB061948
|
BDBM50590375
Cc1cc(C)c(CNC(=O)c2cc(Br)c3c(c2C)OC(C)(C2CCC(N(C)C)CC2)O3)c(=O)[nH]1
|
C26H34BrN3O4 532.479000 |
CHJLMVBYELJCLC-UHFFFAOYSA-N | O14686, O96028, Q03164, Q8NEZ4, Q96L73, Q9BZ95 | Histone-lysine N-methyltransferase, H3 lysine-36 specific, Histone-lysine N-methyltransferase 2A, Histone-lysine N-methyltransferase 2C, Histone-lysine N-methyltransferase NSD3, Histone-lysine N-methyltransferase NSD2, Histone-lysine N-methyltransferase 2D |
BindingDB, PubChem
BindingDB:BDBM50590375; PubChem:CID126482032
|
Local ready
Direct docking supported
|
|
E3L061949
BDB061949
|
BDBM50590813
Cc1c(Cl)ccc2cc(/C=C3\NC(=O)N(C(C(=O)NC(CO)CO)c4ccc(F)c(F)c4)C3=O)[nH]c12
|
C24H21ClF2N4O5 518.904000 |
QCCZDXNQUVNFGP-UWVJOHFNSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50590813
|
Local ready
Direct docking supported
|
|
E3L061950
BDB061950
|
BDBM50590814
CC(C)(C)Oc1cc(C(=O)CC(N)=O)ccc1C1=N[C@@H](c2ccc(C(=O)O)cc2)[C@@H](c2c[nH]c3ccc(Cl)cc23)N1C(=O)N1CCNC(=O)C1
|
C36H35ClN6O7 699.164000 |
OVNGEJRHHJULAD-AJQTZOPKSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50590814
|
Local ready
Direct docking supported
|
|
E3L061951
BDB061951
|
BDBM50590815
COc1cc(Cc2c(-c3ccn(S(=O)(=O)c4ccccc4)c3)[nH]c3ccccc23)cc(O)c1OC
|
C27H24N2O5S 488.565000 |
LOTUGZABONLMPG-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50590815; PubChem:CID168291193
|
Local ready
Direct docking supported
|
|
E3L061952
BDB061952
|
BDBM50590849
C[C@@H](O)[C@@H]1NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)Cc2ccc(cc2)OCCSC[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC1=O
|
C37H52N8O18S 928.928000 |
MMZIIPHPCANRDN-RVMCJEEFSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB
BindingDB:BDBM50590849
|
Local ready
Direct docking supported
|
|
E3L061953
BDB061953
|
BDBM50590855
CN1CCC(=O)NCCSCCS(=O)(=O)CCN(Cc2ccc(C#N)cc2)CC(=O)N[C@@H](Cc2cc3ccc(Cl)cc3[nH]2)C1=O
|
C31H37ClN6O5S2 673.261000 |
NGYBSBQRYYOXPH-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50590855; PubChem:CID168270468
|
Local ready
Direct docking supported
|
|
E3L061954
BDB061954
|
BDBM50590979
CC(C)c1cc(C(=O)N2CC[C@@H](NC(=O)NC3CC3)C2)n[nH]1
|
C15H23N5O2 305.382000 |
WNSMPEBHTSITSG-LLVKDONJSA-N | P29375, P41229 | Lysine-specific demethylase 5A, Lysine-specific demethylase 5C |
BindingDB, PubChem
BindingDB:BDBM50590979; PubChem:CID165412819
|
Local ready
Direct docking supported
|
|
E3L061955
BDB061955
|
BDBM50591316
C[C@@]1(c2cccc(Nc3ccc(C4CC4)nc3)c2Cl)CC(=O)N(C2CCOCC2)C(=N)N1
|
C24H28ClN5O2 453.974000 |
SMWXTFXZNJCTMY-DEOSSOPVSA-N | P00797 | Renin |
BindingDB, PubChem
BindingDB:BDBM50591316; PubChem:CID156198608
|
Local ready
Direct docking supported
|
|
E3L061956
BDB061956
|
BDBM50591317
C[C@H]1C[C@@H](N2C(=N)N[C@](C)(c3cccc(Nc4ccc(C5CC5)nc4)c3Cl)CC2=O)CCO1
|
C25H30ClN5O2 468.001000 |
NRQARCCHBBGTDO-LCAJTWGOSA-N | P00797 | Renin |
BindingDB, PubChem
BindingDB:BDBM50591317; PubChem:CID156198318
|
Local ready
Direct docking supported
|
|
E3L061957
BDB061957
|
BDBM50591318
[H]/N=C1\N[C@](C)(c2cccc(Nc3cnc(C4CC4)nc3)c2Cl)CC(=O)N1[C@H]1CCO[C@@H](C)C1
|
C24H29ClN6O2 468.989000 |
RUZADINCVKIRSK-NPALWHDTSA-N | P00797 | Renin |
BindingDB, PubChem
BindingDB:BDBM50591318; PubChem:CID165412421
|
Local ready
Direct docking supported
|
|
E3L061958
BDB061958
|
BDBM50591320
C[C@H]1C[C@@H](N2C(=N)N[C@](C)(c3cccc(NC(=O)c4cccc(C#N)c4)c3Cl)CC2=O)CCO1
|
C25H26ClN5O3 479.968000 |
AWSRDDSRQUJMAJ-LCAJTWGOSA-N | P00797 | Renin |
BindingDB, PubChem
BindingDB:BDBM50591320; PubChem:CID165413063
|
Local ready
Direct docking supported
|
|
E3L061959
BDB061959
|
BDBM50591422
N=C(N)c1ccc(CNC(=O)c2cnn(Cc3ccccc3)c2)cc1
|
C19H19N5O 333.395000 |
SAVNTVHVERKVOD-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM50591422; PubChem:CID24857697
|
Local ready
Direct docking supported
|
|
E3L061960
BDB061960
|
BDBM50591454
Cc1cccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)ccc3o2)c1
|
C21H14ClN3O4 407.813000 |
FTQBNTYNRDNARK-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM50591454; PubChem:CID23760722
|
Local ready
Direct docking supported
|