| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L064161
BDB064161
|
Vhl-IN-1
Cc1cc(-c2scnc2C)ccc1[C@H](C)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)C1(F)CC1)C(C)(C)C
|
C28H37FN4O4S 544.693000 |
NBHYPBDUODSQHJ-DTPUHQDNSA-N | P40337, Q15369 | Elongin-C, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM50628961; PubChem:CID166904461
|
Local ready
Direct docking supported
|
|
E3L064162
BDB064162
|
BDBM50628962
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)cc1F
|
C27H34F2N4O4S 548.656000 |
DPGPPDKBMUPPOH-WYGDDPHOSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50628962
|
Local ready
Direct docking supported
|
|
E3L064163
BDB064163
|
BDBM50628963
Cc1cc(-c2scnc2C)c(F)cc1[C@H](C)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)C1(F)CC1)C(C)(C)C
|
C28H36F2N4O4S 562.683000 |
CNYARHCDHRBYBK-HPRJPVNHSA-N | P40337, Q15369 | Elongin-C, von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50628963
|
Local ready
Direct docking supported
|
|
E3L064164
BDB064164
|
BDBM50628964
COc1cc(-c2scnc2C)c(F)cc1[C@H](C)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)C1(F)CC1)C(C)(C)C
|
C28H36F2N4O5S 578.682000 |
PWPAOVSRKMPDRI-SKSOZTCFSA-N | P40337, Q15369 | Elongin-C, von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50628964
|
Local ready
Direct docking supported
|
|
E3L064165
BDB064165
|
BDBM50628965
Cc1ncsc1-c1ccc2c(c1)CCC2NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)C1(C#N)CC1)C(C)(C)C
|
C29H35N5O4S 549.697000 |
IFDXDLSMJBBZDR-SCPNEYIQSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50628965
|
Local ready
Direct docking supported
|
|
E3L064166
BDB064166
|
BDBM50628966
Cc1ncsc1-c1cc2c(cc1F)C(NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)C1(C#N)CC1)C(C)(C)C)CC2
|
C29H34FN5O4S 567.687000 |
OYQCDQZUQXJORR-GDCITFSMSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50628966
|
Local ready
Direct docking supported
|
|
E3L064167
BDB064167
|
BDBM50628967
Cc1ncsc1-c1cc2c(cc1F)C(NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)C1(F)CC1)C(C)(C)C)CC2
|
C28H34F2N4O4S 560.667000 |
YTEIJYQXXNZIBS-UUTKHABCSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50628967
|
Local ready
Direct docking supported
|
|
E3L064168
BDB064168
|
BDBM50628968
Cc1ncsc1-c1cc2c(cc1F)C(NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)C1(F)CC1)C(C)(C)C)CCC2
|
C29H36F2N4O4S 574.694000 |
HWXXTNVUYSSVNI-GDCITFSMSA-N | Q15369 | Elongin-C |
BindingDB
BindingDB:BDBM50628968
|
Local ready
Direct docking supported
|
|
E3L064169
BDB064169
|
BDBM50629206
O=C(CC[C@@H]1CCCN1c1cc(C(F)(F)F)c(=O)[nH]n1)N1CCN(c2ncc(C(F)(F)F)cn2)CC1
|
C21H23F6N7O2 519.450000 |
LFYTWGBFZMCREV-AWEZNQCLSA-N | P09874 | Poly [ADP-ribose] polymerase 1 |
BindingDB, PubChem
BindingDB:BDBM50629206; PubChem:CID167228889
|
Local ready
Direct docking supported
|
|
E3L064170
BDB064170
|
BDBM50629224
CCCCC[C@@H]1NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H](C)N(C)C(=O)[C@@H](C)N(C)C(=O)[C@H](Cc2cscn2)NC(=O)[C@H](C)N(C)C(=O)[C@H](CCOC)NC(=O)[C@H]2CCCN2C(=O)[C@H](CC(CC)CC)N(C)C1=O
|
C60H94FN11O11S 1196.543000 |
XIKXRDFBSGQANE-JDPILQOFSA-N | O15151 | Protein Mdm4 |
BindingDB
BindingDB:BDBM50629224
|
Local ready
Direct docking supported
|
|
E3L064171
BDB064171
|
BDBM50629225
COCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)[C@H](C(C)(C)C)NC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H](C)N(C)C(=O)[C@@H](C)N(C)C(=O)[C@H](Cc2cscn2)NC(=O)[C@H](C)N(C)C1=O
|
C62H81ClFN11O11S 1242.914000 |
GDIHHBXNNFCHHL-WPXBTSPOSA-N | O15151 | Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50629225; PubChem:CID172452835
|
Local ready
Direct docking supported
|
|
E3L064172
BDB064172
|
BDBM50629240
Cc1cc(NCCOCCOCCOCCOCCOCCN)ccc1C(=O)Nc1nc(C)c(C)s1
|
C25H40N4O6S 524.684000 |
SGMCCVJYWUQKAO-UHFFFAOYSA-N | Q16531 | DNA damage-binding protein 1 |
BindingDB, PubChem
BindingDB:BDBM50629240; PubChem:CID169689738
|
Local ready
Direct docking supported
|
|
E3L064173
BDB064173
|
BDBM50629300
O=C(c1cc(CC2=NOB(O)c3ccccc32)ccc1F)N1CCN(C(=O)C2CC2)CC1
|
C23H23BFN3O4 435.264000 |
MWHOMSOVXNBBOR-UHFFFAOYSA-N | P09874 | Poly [ADP-ribose] polymerase 1 |
BindingDB, PubChem
BindingDB:BDBM50629300; PubChem:CID172466129
|
Local ready
Direct docking supported
|
|
E3L064174
BDB064174
|
[1-(3-Fluorophenyl)-3-pyrrolidinyl]methanamine
NCC1CCN(c2cccc(F)c2)C1
|
C11H15FN2 194.253000 |
UBVVTRXMBZDJIL-UHFFFAOYSA-N | Q12830 | Nucleosome-remodeling factor subunit BPTF |
BindingDB, PubChem
BindingDB:BDBM50629487; PubChem:CID24275319
|
Local ready
Direct docking supported
|
|
E3L064175
BDB064175
|
6-(piperazin-1-yl)-N-(p-tolyl)pyridazin-3-amine
Cc1ccc(Nc2ccc(N3CCNCC3)nn2)cc1
|
C15H19N5 269.352000 |
YNLJUHXPRUKMKO-UHFFFAOYSA-N | Q12830 | Nucleosome-remodeling factor subunit BPTF |
BindingDB, PubChem
BindingDB:BDBM50629488; PubChem:CID33702632
|
Local ready
Direct docking supported
|
|
E3L064176
BDB064176
|
BDBM50629489
N#Cc1c(N)sc2c1CCCC2
|
C9H10N2S 178.260000 |
ADHVMGAFAKSNOM-UHFFFAOYSA-N | Q12830 | Nucleosome-remodeling factor subunit BPTF |
BindingDB, PubChem
BindingDB:BDBM50629489; PubChem:CID78382
|
Local ready
Direct docking supported
|
|
E3L064177
BDB064177
|
1-(1-Adamantylacetyl)pyrrolidine
O=C(CC12CC3CC(CC(C3)C1)C2)N1CCCC1
|
C16H25NO 247.382000 |
PCDBBNAUNRHBLR-UHFFFAOYSA-N | Q12830 | Nucleosome-remodeling factor subunit BPTF |
BindingDB, PubChem
BindingDB:BDBM50629490; PubChem:CID2835983
|
Local ready
Direct docking supported
|
|
E3L064178
BDB064178
|
2-Phenyl-octahydropyrrolo(3,4-c)pyrrole
c1ccc(N2CC3CNCC3C2)cc1
|
C12H16N2 188.274000 |
ZPKIUZZZFIZELT-UHFFFAOYSA-N | Q12830 | Nucleosome-remodeling factor subunit BPTF |
BindingDB, PubChem
BindingDB:BDBM50629491; PubChem:CID12958527
|
Local ready
Direct docking supported
|
|
E3L064179
BDB064179
|
BDBM50629492
CC(=O)N1CCN(c2ccc(Nc3ccc(C)cc3)nn2)CC1
|
C17H21N5O 311.389000 |
CRSZQACQJBWSQK-UHFFFAOYSA-N | Q12830 | Nucleosome-remodeling factor subunit BPTF |
BindingDB, PubChem
BindingDB:BDBM50629492; PubChem:CID49671307
|
Local ready
Direct docking supported
|
|
E3L064180
BDB064180
|
BDBM50629493
N#Cc1c(N)sc2c1CCCCC2
|
C10H12N2S 192.287000 |
GBQACFCEZPKMTA-UHFFFAOYSA-N | Q12830 | Nucleosome-remodeling factor subunit BPTF |
BindingDB, PubChem
BindingDB:BDBM50629493; PubChem:CID605976
|
Local ready
Direct docking supported
|