| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006561
BDB006561
|
BDBM147452
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)N3CC[C@H](O)C3)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12
|
C40H43N3O3 613.802000 |
XTFQFEYOJFTXMU-FOPBOCKXSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147452; PubChem:CID71074747
|
Local ready
Direct docking supported
|
|
E3L006562
BDB006562
|
BDBM147453
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)NCCO)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12
|
C38H41N3O3 587.764000 |
GVFZTMVQEABQLW-SANMLTNESA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147453; PubChem:CID71075289
|
Local ready
Direct docking supported
|
|
E3L006563
BDB006563
|
BDBM147454
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)NC[C@@H](O)C(=O)N(C)C)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12
|
C41H46N4O4 658.843000 |
MGYJOCPLMCIQNO-MAGLAKDHSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147454; PubChem:CID71074877
|
Local ready
Direct docking supported
|
|
E3L006564
BDB006564
|
BDBM147455
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)NCCN(C)C)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12
|
C40H46N4O2 614.834000 |
MDDWRIHIIAFAGR-NDEPHWFRSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147455; PubChem:CID71074838
|
Local ready
Direct docking supported
|
|
E3L006565
BDB006565
|
BDBM147456
CNC(=O)c1ccccc1-c1ccc(Cn2c(C)c(C)c3cc(C(=O)N[C@@H](C)c4cccc(C(C)C)c4)ccc32)cc1
|
C37H39N3O2 557.738000 |
PAGXYYLAMNCOQL-VWLOTQADSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147456; PubChem:CID71074989
|
Local ready
Direct docking supported
|
|
E3L006566
BDB006566
|
BDBM147457
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)N(C)C)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12
|
C38H41N3O2 571.765000 |
KUHLANITMBTBHT-SANMLTNESA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147457; PubChem:CID71074751
|
Local ready
Direct docking supported
|
|
E3L006567
BDB006567
|
BDBM147458
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)NO)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12
|
C36H37N3O3 559.710000 |
CVCGPWWVROZGTB-DEOSSOPVSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147458; PubChem:CID71478388
|
Local ready
Direct docking supported
|
|
E3L006568
BDB006568
|
BDBM147459
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)NS(C)(=O)=O)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12
|
C37H39N3O4S 621.803000 |
ZSVUSKZAVSZXCS-VWLOTQADSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147459; PubChem:CID71075482
|
Local ready
Direct docking supported
|
|
E3L006569
BDB006569
|
BDBM147460
Cc1c(C)n(Cc2ccc(-c3ccccc3C(N)=O)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12
|
C36H37N3O2 543.711000 |
GJPASUXMVRHPLJ-DEOSSOPVSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM147460; PubChem:CID71075678
|
Local ready
Direct docking supported
|
|
E3L006570
BDB006570
|
BDBM148140
CC(C)c1ccnc(-c2nc3cc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C29H39N5O2 489.664000 |
DKRATAAOKANKRM-VAMGGRTRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148140
|
Local ready
Direct docking supported
|
|
E3L006571
BDB006571
|
BDBM148141
C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3c3nccs3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H29ClN8O2S 577.114000 |
QZDUEEVKTBNATM-HOIFWPIMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148141
|
Local ready
Direct docking supported
|
|
E3L006572
BDB006572
|
BDBM148142
CC(C)[C@@H]1C[C@@H](O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H34ClN7O3 552.079000 |
DRCNKQOCYYDHQY-UYWGQIMJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148142
|
Local ready
Direct docking supported
|
|
E3L006573
BDB006573
|
BDBM148143
CO[C@H]1COC[C@@H]1N(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1
|
C27H32ClN7O4 554.051000 |
JAADWIRZYMCBKA-WZRIXLNXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM148143; PubChem:CID136216300
|
Local ready
Direct docking supported
|
|
E3L006574
BDB006574
|
BDBM148144
CCN(C)C(=O)[C@@H]1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H35ClN8O3 579.105000 |
ONERYIXOXCAEEX-BSRJHKFKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148144
|
Local ready
Direct docking supported
|
|
E3L006575
BDB006575
|
BDBM148145
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CN(C(=O)OCc5ccccc5)CC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C36H39ClN8O5 699.212000 |
JIOKQGPNZGDGSQ-IIJZBOQJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148145
|
Local ready
Direct docking supported
|
|
E3L006576
BDB006576
|
BDBM148146
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CNCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H33ClN8O3 565.078000 |
ZUQDCSQDHXMAEE-IEGYKGNPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148146
|
Local ready
Direct docking supported
|
|
E3L006577
BDB006577
|
BDBM148147
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CN(Cc5ccccc5)CC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C35H39ClN8O3 655.203000 |
PDFUVLMSDRPILV-FHMYSUAKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148147
|
Local ready
Direct docking supported
|
|
E3L006578
BDB006578
|
BDBM148148
CC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C29H35ClN8O3 579.105000 |
BUJZZMJMJZZYFJ-SOAMZJECSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148148
|
Local ready
Direct docking supported
|
|
E3L006579
BDB006579
|
BDBM148149
CCOC(c1nc2cc(-c3n[nH]c(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
|
C29H36ClN7O2 550.107000 |
BUBTUDNKMKSAHZ-XYCFSGNMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148149
|
Local ready
Direct docking supported
|
|
E3L006580
BDB006580
|
BDBM148150
CCOC(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
|
C32H36ClN5O3 574.125000 |
FNAMBLUKCRUASU-VPYPWEPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM148150
|
Local ready
Direct docking supported
|