| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L011601
BDB011601
|
BDBM238966
COc1ccc(-n2nnc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)c(Cl)c1
|
C22H27ClN6O3 458.950000 |
FODUFECSLYLXJO-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238966; PubChem:CID118513266
|
Local ready
Direct docking supported
|
|
E3L011602
BDB011602
|
BDBM238967
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(Cl)cc1Cl
|
C21H24Cl2N6O2 463.369000 |
LVMFPVUIWOOJNY-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238967; PubChem:CID118513302
|
Local ready
Direct docking supported
|
|
E3L011603
BDB011603
|
BDBM238968
COc1ccc(-n2nnc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)c(C(F)(F)F)c1
|
C23H27F3N6O3 492.502000 |
NGQWUQYESZDKHI-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238968; PubChem:CID118513288
|
Local ready
Direct docking supported
|
|
E3L011604
BDB011604
|
BDBM238969
COc1ccc(-n2nnc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)cc1C
|
C23H30N6O3 438.532000 |
SMEJNAIKZQKEDP-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238969; PubChem:CID118513263
|
Local ready
Direct docking supported
|
|
E3L011605
BDB011605
|
BDBM238970
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(OC(F)(F)F)cc1Cl
|
C22H24ClF3N6O3 512.920000 |
WXVDTPRGJZKZPF-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238970; PubChem:CID118513279
|
Local ready
Direct docking supported
|
|
E3L011606
BDB011606
|
BDBM238971
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(Cl)cc1
|
C21H25ClN6O2 428.924000 |
KSOXQHSQZWSLIA-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238971; PubChem:CID118513299
|
Local ready
Direct docking supported
|
|
E3L011607
BDB011607
|
BDBM238972
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)nnn1-c1ccc(Cl)cc1Cl
|
C21H17Cl2FN6O2 475.311000 |
MOKGJPFJPBCJGY-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238972; PubChem:CID118513298
|
Local ready
Direct docking supported
|
|
E3L011608
BDB011608
|
BDBM238973
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)nnn1-c1ccc(Cl)cc1
|
C21H18ClFN6O2 440.866000 |
SQLLXHARKNGURD-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238973; PubChem:CID118513301
|
Local ready
Direct docking supported
|
|
E3L011609
BDB011609
|
BDBM238974
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)nnn1-c1ccc(OC(F)(F)F)cc1Cl
|
C22H17ClF4N6O3 524.862000 |
JMXMZZABLCOWIP-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238974; PubChem:CID118513277
|
Local ready
Direct docking supported
|
|
E3L011610
BDB011610
|
Smurf1-IN-1
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(C2CC2)cc1Cl
|
C24H29ClN6O2 468.989000 |
DJCHYTWZRDUVHQ-UHFFFAOYSA-N | Q9HAU4, Q9HCE7 | E3 ubiquitin-protein ligase SMURF1, E3 ubiquitin-protein ligase SMURF2 |
BindingDB, PubChem
BindingDB:BDBM238975; PubChem:CID118513267
|
Local ready
Direct docking supported
|
|
E3L011611
BDB011611
|
BDBM238976
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)nnn1-c1ccc(C2CC2)cc1Cl
|
C24H22ClFN6O2 480.931000 |
ACXUNKGGFBQCSH-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238976; PubChem:CID118513269
|
Local ready
Direct docking supported
|
|
E3L011612
BDB011612
|
BDBM238978
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)nnn1-c1ccc(Cl)cc1C1CC1
|
C24H22ClFN6O2 480.931000 |
RZYISIGSIXJKBN-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238978; PubChem:CID118513270
|
Local ready
Direct docking supported
|
|
E3L011613
BDB011613
|
BDBM238979
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(Cl)cc1C1CC1
|
C24H29ClN6O2 468.989000 |
ISFJQKFPHDUWPE-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238979; PubChem:CID118513300
|
Local ready
Direct docking supported
|
|
E3L011614
BDB011614
|
BDBM238980
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(F)cc1C1CC1
|
C24H29FN6O2 452.534000 |
LEXOBXPBMTWDHU-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238980; PubChem:CID118513293
|
Local ready
Direct docking supported
|
|
E3L011615
BDB011615
|
BDBM238981
Cc1c(NC(=O)c2nnn3c2CCCc2cc(OC(F)(F)F)ccc2-3)c(=O)n(C2CCCCC2)n1C
|
C24H27F3N6O3 504.513000 |
NOVSDVCDYPGXAQ-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238981; PubChem:CID92131116
|
Local ready
Direct docking supported
|
|
E3L011616
BDB011616
|
BDBM238982
COc1ccc(-n2nnc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)cc1
|
C22H28N6O3 424.505000 |
GPKSXWTVPBSUBX-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM238982; PubChem:CID118513278
|
Local ready
Direct docking supported
|
|
E3L011617
BDB011617
|
BDBM239091
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC(C(C)C)CC1
|
C25H36N4O3 440.588000 |
HRTYJBLUZWWQGU-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM239091; PubChem:CID118511061
|
Local ready
Direct docking supported
|
|
E3L011618
BDB011618
|
BDBM239092
CCC1CC(C)CC=C1c1onc(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)c1C
|
C25H36N4O3 440.588000 |
ZTQNBNARQOOMPR-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM239092; PubChem:CID118511162
|
Local ready
Direct docking supported
|
|
E3L011619
BDB011619
|
BDBM239093
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCCCC1(C)C
|
C24H34N4O3 426.561000 |
DGNFKQCNOKELPI-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM239093; PubChem:CID118511111
|
Local ready
Direct docking supported
|
|
E3L011620
BDB011620
|
BDBM239094
CCC1CC=C(c2onc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)CC1
|
C24H34N4O3 426.561000 |
JIQMNVDEYFAWTD-UHFFFAOYSA-N | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 |
BindingDB, PubChem
BindingDB:BDBM239094; PubChem:CID118511131
|
Local ready
Direct docking supported
|