| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L014301
BDB014301
|
BDBM323597
C/C(=C\C(=O)O)CCCOc1ccccc1CN(C)C(=O)c1ccc(-c2ccco2)cc1
|
C26H27NO5 433.504000 |
HMOHAOWFXBETRA-HTXNQAPBSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM323597; PubChem:CID121269378
|
Local ready
Direct docking supported
|
|
E3L014302
BDB014302
|
BDBM323599
C/C(=C\CCCOc1ccccc1CN(C)C(=O)c1ccc(-c2ccco2)cc1)C(=O)O
|
C26H27NO5 433.504000 |
UOUIWYBSJFMAKV-UFWORHAWSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM323599; PubChem:CID121269406
|
Local ready
Direct docking supported
|
|
E3L014303
BDB014303
|
BDBM323603
CC(CCCCOc1ccccc1CN(C)C(=O)c1ccc(-c2ccco2)cc1)C(=O)O
|
C26H29NO5 435.520000 |
HASKDUVBSFNKIR-UHFFFAOYSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM323603; PubChem:CID121269424
|
Local ready
Direct docking supported
|
|
E3L014304
BDB014304
|
BDBM323607
CN(Cc1ccccc1OCCCCC(C)(C)C(=O)O)C(=O)c1ccc(-c2ccco2)cc1
|
C27H31NO5 449.547000 |
RDTZXAYSBVNVKN-UHFFFAOYSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM323607; PubChem:CID121277016
|
Local ready
Direct docking supported
|
|
E3L014305
BDB014305
|
BDBM323616
CN(Cc1ccccc1OCCC/C=C/C(=O)O)C(=O)c1ccc(-c2ccco2)cc1
|
C25H25NO5 419.477000 |
PRLUQZAEJIZRCO-QDEBKDIKSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor alpha |
BindingDB, PubChem
BindingDB:BDBM323616; PubChem:CID121269382
|
Local ready
Direct docking supported
|
|
E3L014306
BDB014306
|
US10188627, Comparator Cmpd. 1
CN(Cc1ccccc1OCCCCCC(=O)O)C(=O)c1ccc(-c2ccco2)cc1
|
C25H27NO5 421.493000 |
COKSUAQUYUTOFS-UHFFFAOYSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor alpha |
BindingDB, PubChem
BindingDB:BDBM323617; PubChem:CID117629817
|
Local ready
Direct docking supported
|
|
E3L014307
BDB014307
|
Biib-091
Cn1cc(Nc2nccc(-c3ccc4c(c3)CN(C3COC3)CC[C@H]4NC(=O)c3cn(C(C)(C)C)nn3)n2)cn1
|
C28H34N10O2 542.648000 |
JSAQBOQCZJHWMA-XMMPIXPASA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM324284; PubChem:CID135355941
|
Local ready
Direct docking supported
|
|
E3L014308
BDB014308
|
BDBM326287
Cc1ccc(F)c(-c2cc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H26F4N4O2 526.534000 |
SSLMPUKAUBJZCY-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326287; PubChem:CID76684131
|
Local ready
Direct docking supported
|
|
E3L014309
BDB014309
|
BDBM326288
Cc1ccc(F)c(-c2cn(Cc3ccc(C(F)(F)F)cc3)c3c(N[C@H](C)C4CCC4)nc(C(=O)O)nc23)c1
|
C28H26F4N4O2 526.534000 |
WBSCQEVSUDGIRA-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326288; PubChem:CID76684310
|
Local ready
Direct docking supported
|
|
E3L014310
BDB014310
|
BDBM326289
Cc1cccc(-c2cc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H27F3N4O2 508.544000 |
WLLKNSQMTNCFQR-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326289; PubChem:CID76684217
|
Local ready
Direct docking supported
|
|
E3L014311
BDB014311
|
BDBM326290
Cc1cccc(-c2c(C)c3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H29F3N4O2 522.571000 |
NJVOPBLDDWXZHO-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326290; PubChem:CID76684128
|
Local ready
Direct docking supported
|
|
E3L014312
BDB014312
|
BDBM326291
COc1ccc(C)cc1-c1cc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H29F3N4O3 538.570000 |
WNYSSBIIZUUQDA-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326291; PubChem:CID76684130
|
Local ready
Direct docking supported
|
|
E3L014313
BDB014313
|
BDBM326292
C[C@@H](Nc1nc(C(=O)O)nc2cc(-c3ccc4occc4c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H25F3N4O3 534.538000 |
YXSGUEZTKKJGQA-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326292; PubChem:CID76684129
|
Local ready
Direct docking supported
|
|
E3L014314
BDB014314
|
BDBM326293
Cc1ccc(Cl)c(-c2cc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H26ClF3N4O2 542.989000 |
WSYPBBWCMMCMNV-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326293; PubChem:CID76683803
|
Local ready
Direct docking supported
|
|
E3L014315
BDB014315
|
BDBM326294
Cc1ccc(Cl)c(-c2cn(Cc3ccc(C(F)(F)F)cc3)c3c(N[C@H](C)C4CCC4)nc(C(=O)O)nc23)c1
|
C28H26ClF3N4O2 542.989000 |
IFANBBYGGPFMJC-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326294; PubChem:CID76683802
|
Local ready
Direct docking supported
|
|
E3L014316
BDB014316
|
BDBM326295
Cc1ccnc(-c2cc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H26F3N5O2 509.532000 |
PFNSAJRDSJBRTM-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326295; PubChem:CID76684311
|
Local ready
Direct docking supported
|
|
E3L014317
BDB014317
|
BDBM326296
CC(C)c1ccnc(-c2cc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H30F3N5O2 537.586000 |
WGNSFENCDDRRRJ-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326296; PubChem:CID76684312
|
Local ready
Direct docking supported
|
|
E3L014318
BDB014318
|
BDBM326297
Cc1c(-c2cc(C(C)C)ccn2)n(Cc2ccc(C(F)(F)F)cc2)c2c(N[C@H](C)C3CCC3)nc(C(=O)O)nc12
|
C30H32F3N5O2 551.613000 |
APXXDNUBPLJXKY-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326297; PubChem:CID76683804
|
Local ready
Direct docking supported
|
|
E3L014319
BDB014319
|
BDBM326298
Cc1cccc(-c2cc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2N)c1
|
C28H28F3N5O2 523.559000 |
VYAHCRMFIULLEO-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326298; PubChem:CID76683909
|
Local ready
Direct docking supported
|
|
E3L014320
BDB014320
|
BDBM326299
Cc1cccc(-c2cc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cn2)c1
|
C27H26F3N5O2 509.532000 |
SDIOICKVNADFJN-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM326299; PubChem:CID76684027
|
Local ready
Direct docking supported
|