| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L014681
BDB014681
|
US9751837, Example 17(am)
COc1c(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc(C(=O)O)c(N(C)C)c4)c3)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O
|
C37H40N6O7S 712.829000 |
CWEBLBDEUUBLRL-UHFFFAOYSA-N | Q13490 | Baculoviral IAP repeat-containing protein 2 |
BindingDB, PubChem
BindingDB:BDBM337707; PubChem:CID121255362
|
Local ready
Direct docking supported
|
|
E3L014682
BDB014682
|
BDBM339930
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@](C)(Cc2ccc(C(=O)O)c[n+]2[O-])O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H36Cl2N2O7S 675.631000 |
UFMQNHQVIXKCIT-LNHQPZRBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM339930
|
Local ready
Direct docking supported
|
|
E3L014683
BDB014683
|
BDBM339931
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)c[n+]2[O-])O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H36Cl2N2O7S 675.631000 |
UFMQNHQVIXKCIT-OZLMZZSTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM339931
|
Local ready
Direct docking supported
|
|
E3L014684
BDB014684
|
BDBM339932
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)s2)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
|
C31H33Cl2FN2O6S2 683.651000 |
GOYFACGYNALWDU-HYHFPRINSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM339932
|
Local ready
Direct docking supported
|
|
E3L014685
BDB014685
|
BDBM339933
COC(=O)c1ccc(C[C@]2(C)O[C@H](c3cccc(Cl)c3)C(c3ccc(Cl)c(F)c3)N([C@H](CSC(C)(C)C)C3CC3)C2=O)nc1
|
C34H37Cl2FN2O4S 659.651000 |
MJNPIZNGWNFUEK-IKPQEFNOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM339933
|
Local ready
Direct docking supported
|
|
E3L014686
BDB014686
|
BDBM339934
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)cn2)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
|
C33H35Cl2FN2O6S 677.622000 |
ILRYIEMVGUAAAV-OZLMZZSTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM339934
|
Local ready
Direct docking supported
|
|
E3L014687
BDB014687
|
US9763922, Example 1
CC(=O)N1CCc2c(c(Nc3ccc(C)c(-c4cnn(C)c4)c3)nn2C)C1
|
C20H24N6O 364.453000 |
SALOBVZIWAMSKM-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340470; PubChem:CID121365279
|
Local ready
Direct docking supported
|
|
E3L014688
BDB014688
|
US9763922, Example 2
CC(=O)N1CCc2c(c(Nc3ccc(-c4cnn(C)c4)cc3F)nn2C)C1
|
C19H21FN6O 368.416000 |
VDJAZZIRPGNQHN-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340471; PubChem:CID121373406
|
Local ready
Direct docking supported
|
|
E3L014689
BDB014689
|
US9763922, Example 3
CC(=O)N1CCc2c(c(Nc3cccc(-c4cnn(C)c4)c3F)nn2C)C1
|
C19H21FN6O 368.416000 |
GGJYCLABUGOGBK-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340472; PubChem:CID121373402
|
Local ready
Direct docking supported
|
|
E3L014690
BDB014690
|
US9763922, Example 4
CC(=O)N1CCc2c(c(Nc3c(F)ccc(-c4cnn(C)c4)c3F)nn2C)C1
|
C19H20F2N6O 386.406000 |
MAQGJYSQPCZDAO-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340473; PubChem:CID138805943
|
Local ready
Direct docking supported
|
|
E3L014691
BDB014691
|
US9763922, Example 5
CC(=O)N1CCc2c(c(Nc3cc(F)cc(-c4cnn(C)c4)c3)nn2C)C1
|
C19H21FN6O 368.416000 |
GUIQEFCTYNFOAZ-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340474; PubChem:CID121373407
|
Local ready
Direct docking supported
|
|
E3L014692
BDB014692
|
US9763922, Example 6
CC(=O)N1CCc2c(c(Nc3ccc(F)c(-c4cnn(C)c4)c3)nn2C)C1
|
C19H21FN6O 368.416000 |
ZLYPTONLFSSETB-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340475; PubChem:CID121373389
|
Local ready
Direct docking supported
|
|
E3L014693
BDB014693
|
US9763922, Example 7
CC(=O)N1CCc2c(c(Nc3ccc(-c4cnn(C)c4)c(F)c3)nn2C)C1
|
C19H21FN6O 368.416000 |
UXZNKSCGUAMAKW-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340476; PubChem:CID121373383
|
Local ready
Direct docking supported
|
|
E3L014694
BDB014694
|
BDBM340477
CC(=O)N1CCc2c(c(Nc3cnn(C)c3)nn2C)C1
|
C13H18N6O 274.328000 |
YIEMXFRGRQSGCW-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340477; PubChem:CID121373391
|
Local ready
Direct docking supported
|
|
E3L014695
BDB014695
|
US9763922, Example 9
CC(=O)N1CCc2c(c(Nc3ccc(-n4cncn4)cc3)nn2C)C1
|
C17H19N7O 337.387000 |
CHDWUVQPNVCEHR-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340478; PubChem:CID121373785
|
Local ready
Direct docking supported
|
|
E3L014696
BDB014696
|
US9763922, Example 10
CC(=O)N1CCc2c(c(Nc3cccc(-n4cncn4)c3)nn2C)C1
|
C17H19N7O 337.387000 |
LKKJNTMSGABUCU-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340479; PubChem:CID121373390
|
Local ready
Direct docking supported
|
|
E3L014697
BDB014697
|
US9763922, Example 11
CC(=O)N1CCc2c(c(Nc3ccc4cn(C)nc4c3)nn2C)C1
|
C17H20N6O 324.388000 |
YRTHFRBBOGXINJ-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340480; PubChem:CID121373782
|
Local ready
Direct docking supported
|
|
E3L014698
BDB014698
|
US9763922, Example 12
CC(=O)N1CCc2c(c(Nc3cccc(-c4cnco4)c3)nn2C)C1
|
C18H19N5O2 337.383000 |
UHKKPBKHDORUNF-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340481; PubChem:CID121373393
|
Local ready
Direct docking supported
|
|
E3L014699
BDB014699
|
US9763922, Example 13
CC(=O)N1CCc2c(c(Nc3ccc(-c4cnco4)cc3)nn2C)C1
|
C18H19N5O2 337.383000 |
YMAXEEGVRDKHCS-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340482; PubChem:CID121383057
|
Local ready
Direct docking supported
|
|
E3L014700
BDB014700
|
US9763922, Example 14
CC(=O)N1CCc2c(c(Nc3ccc4cnn(C)c4c3)nn2C)C1
|
C17H20N6O 324.388000 |
HDNVELJYMSTJBT-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM340483; PubChem:CID121373386
|
Local ready
Direct docking supported
|