| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L001901
BDB001901
|
BDBM35066
CC(C)CCCCNC(=O)N(CC(CCC(=O)O)NC(N)=O)C(CCCCN)CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1
|
C47H74Br2N10O9 1082.978000 |
YKCYFUAYXTYASE-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM35066
|
Local ready
Direct docking supported
|
|
E3L001902
BDB001902
|
BDBM35067
NCCCCC(CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)N(CC(CCC(=O)O)NC(N)=O)C(=O)NCCCc1ccccc1
|
C49H70Br2N10O9 1102.968000 |
HXULERBXKAXYNW-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM35067
|
Local ready
Direct docking supported
|
|
E3L001903
BDB001903
|
BDBM35068
COc1ccc(CCCNC(=O)N(CC(CCC(=O)O)NC(N)=O)C(CCCCN)CN(C(=O)NCCc2ccc(Br)cc2)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc2ccc(Br)cc2)cc1
|
C50H72Br2N10O10 1132.994000 |
JVVSGXRWHNQKGL-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35068
|
Local ready
Direct docking supported
|
|
E3L001904
BDB001904
|
BDBM35069
NCCCCC(CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)N(CC(CCC(=O)O)NC(N)=O)C(=O)NCCCc1ccc([N+](=O)[O-])cc1
|
C49H69Br2N11O11 1147.965000 |
YXBPQVQRJCCXGV-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM35069
|
Local ready
Direct docking supported
|
|
E3L001905
BDB001905
|
BDBM35070
NCCCCC(CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)N(CC(CCC(=O)O)NC(N)=O)C(=O)NCCCc1ccc(Br)cc1
|
C49H69Br3N10O9 1181.864000 |
FZAMJDTYJYGDFF-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM35070
|
Local ready
Direct docking supported
|
|
E3L001906
BDB001906
|
BDBM35071
NCCCCC(CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)N(CC(CCC(=O)O)NC(N)=O)C(=O)NCCCC1CCCCC1
|
C49H76Br2N10O9 1109.016000 |
HNLKTYSAPFGWPW-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM35071
|
Local ready
Direct docking supported
|
|
E3L001907
BDB001907
|
BDBM35072
NCCCCC(CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)N(CC(CCC(=O)O)NC(=O)Nc1ccccc1)C(=O)NCCCC1CCCCC1
|
C55H80Br2N10O9 1185.114000 |
SNZPICQSGNGTHW-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35072
|
Local ready
Direct docking supported
|
|
E3L001908
BDB001908
|
BDBM35073
C=CCNC(=O)NC(CCC(=O)O)CN(C(=O)NCCCC1CCCCC1)C(CCCCN)CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1
|
C52H80Br2N10O9 1149.081000 |
ZMGZFCVVUBJBAF-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35073
|
Local ready
Direct docking supported
|
|
E3L001909
BDB001909
|
BDBM35074
NCCCCC(CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)N(CC(CCC(=O)O)NC(=O)NCC1CCCCC1)C(=O)NCCCC1CCCCC1
|
C56H88Br2N10O9 1205.189000 |
ILRKSYCYZCXIFW-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM35074
|
Local ready
Direct docking supported
|
|
E3L001910
BDB001910
|
BDBM35075
NCCCCC(CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)N(CC(CCC(=O)O)NC(=O)[C@@H]1CCCN1)C(=O)NCCCC1CCCCC1
|
C53H82Br2N10O9 1163.108000 |
ASQXURAXPYLIJU-DTPPOCSKSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35075
|
Local ready
Direct docking supported
|
|
E3L001911
BDB001911
|
BDBM35076
CC(C)CCC(=O)NC(CCC(=O)O)CN(C(=O)NCCCC1CCCCC1)C(CCCCN)CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1
|
C54H85Br2N9O9 1164.136000 |
IEQDZRWPNBKWNA-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35076
|
Local ready
Direct docking supported
|
|
E3L001912
BDB001912
|
BDBM35077
NCCCCC(CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(Br)cc1)N(CC(CCC(=O)O)NC(=O)CCC1CCCCC1)C(=O)NCCCC1CCCCC1
|
C57H89Br2N9O9 1204.201000 |
ZENXIMUXWXBCEI-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35077
|
Local ready
Direct docking supported
|
|
E3L001913
BDB001913
|
BDBM35078
CC(C)CCC(=O)NC(CCC(=O)O)CN(C(=O)NCCCC1CCCCC1)C(CCCCN)CN(C(=O)NCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(F)cc1
|
C54H85BrFN9O9 1103.230000 |
MNIASBCRMYNSSY-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35078
|
Local ready
Direct docking supported
|
|
E3L001914
BDB001914
|
BDBM35079
Cc1ccc(CCNC(=O)N(CC(CCCCN)N(CC(CCC(=O)O)NC(=O)CCC(C)C)C(=O)NCCCC2CCCCC2)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc2ccc(Br)cc2)cc1
|
C55H88BrN9O9 1099.267000 |
AIEANSDAMZZZRZ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM35079
|
Local ready
Direct docking supported
|
|
E3L001915
BDB001915
|
BDBM35080
Cc1ccc(CCNC(=O)N(CC(CCCCN)N(CC(CCC(=O)O)NC(=O)CCC(C)C)C(=O)NCCCC2CCCCC2)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc2ccc(F)cc2)cc1
|
C55H88FN9O9 1038.361000 |
MSMPCMQXSXQQJE-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35080
|
Local ready
Direct docking supported
|
|
E3L001916
BDB001916
|
BDBM35081
Cc1ccc(CCNC(=O)N(CC(CCCCN)N(CC(CCC(=O)O)NC(=O)CCC(C)C)C(=O)NCCCC2CCCCC2)C(CCC(=O)O)CN(CCC(N)=O)C(=O)NCCCCc2ccc(F)cc2)cc1
|
C56H90FN9O9 1052.388000 |
CCIFGPJUSMTRPS-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35081
|
Local ready
Direct docking supported
|
|
E3L001917
BDB001917
|
BDBM35083
CC(C)CCC(=O)N[C@@H](CCCC(=O)O)CN(C(=O)NCCCC1CCCCC1)[C@@H](CCCCN)CN(C(=O)NCCc1ccc(Br)cc1)[C@@H](CCCC(=O)O)CN(CCC(N)=O)C(=O)NCCCc1ccc(F)cc1
|
C56H89BrFN9O9 1131.284000 |
HGWRCUJWOGQOJP-HYGNTPKVSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM35083
|
Local ready
Direct docking supported
|
|
E3L001918
BDB001918
|
BDBM35085
CC(C)CCC(=O)NC(CCC(=O)O)CN(CCCCCC1CCCCC1)C(CCCCN)CN(CCCCc1ccc(Br)cc1)C(CCC(=O)O)CN(CCCCCc1ccc(F)cc1)CCC(N)=O
|
C57H94BrFN6O6 1058.317000 |
ZTCITBUWKSYRAF-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM35085
|
Local ready
Direct docking supported
|
|
E3L001919
BDB001919
|
BDBM35362
N#Cc1c(NC(=O)c2ccc(Br)o2)n(-c2ccccc2)c2nc3ccccc3nc12
|
C22H12BrN5O2 458.275000 |
NGFYSVJWYNOJNU-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM35362; PubChem:CID658921
|
Local ready
Direct docking supported
|
|
E3L001920
BDB001920
|
BDBM35368
CCCCNC(=O)c1c(N)n(CCCOC)c2nc3ccccc3nc12
|
C19H25N5O2 355.442000 |
GQXAAZWBUIPYAF-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM35368; PubChem:CID662864
|
Local ready
Direct docking supported
|