| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L024141
BDB024141
|
US11274090, Example 25 Isomer 2
COc1cc(NC(=O)[C@H](NCCc2ccc(C#N)cc2)c2ccccc2)ccc1-c1cnn(C)c1
|
C28H27N5O2 465.557000 |
DNETUIUEXGZOQD-HHHXNRCGSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542125; PubChem:CID156273063
|
Local ready
Direct docking supported
|
|
E3L024142
BDB024142
|
US11274090, Example 26 Isomer 1
Cn1cc(-c2ccc(NC(=O)[C@@H](NCCc3ccc(C#N)cc3)c3ccccc3)c(Cl)c2)cn1
|
C27H24ClN5O 469.976000 |
RCLOEGRDGOYCST-SANMLTNESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542126; PubChem:CID139426280
|
Local ready
Direct docking supported
|
|
E3L024143
BDB024143
|
US11274090, Example 26 Isomer 2
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)c(Cl)c2)cn1
|
C27H24ClN5O 469.976000 |
RCLOEGRDGOYCST-AREMUKBSSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542127; PubChem:CID156273018
|
Local ready
Direct docking supported
|
|
E3L024144
BDB024144
|
US11274090, Example 27 Isomer 1
Cn1cc(-c2ccc(NC(=O)[C@@H](NCCc3ccc(C#N)cc3)c3ccccc3)cc2Cl)cn1
|
C27H24ClN5O 469.976000 |
SYEHLZPYPNJUOI-SANMLTNESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542128; PubChem:CID139426101
|
Local ready
Direct docking supported
|
|
E3L024145
BDB024145
|
US11274090, Example 27 Isomer 2
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)cc2Cl)cn1
|
C27H24ClN5O 469.976000 |
SYEHLZPYPNJUOI-AREMUKBSSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542129; PubChem:CID156273023
|
Local ready
Direct docking supported
|
|
E3L024146
BDB024146
|
US11274090, Example 28 Isomer 1
Cc1cn(-c2ccc(NC(=O)C(NCCc3ccc(C#N)cc3)c3ccccc3)nc2)cn1
|
C26H24N6O 436.519000 |
GXYYKTSDZYFUDV-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542130; PubChem:CID139425885
|
Local ready
Direct docking supported
|
|
E3L024147
BDB024147
|
US11274090, Example 28 Isomer 2
Cc1cn(-c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)nc2)cn1
|
C26H24N6O 436.519000 |
GXYYKTSDZYFUDV-RUZDIDTESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542131; PubChem:CID156273106
|
Local ready
Direct docking supported
|
|
E3L024148
BDB024148
|
US11274090, Example 29 Isomer 1
Cn1cc(-c2ccc(NC(=O)[C@@H](NCCc3ccc(C#N)cc3F)c3ccccc3)nc2)cn1
|
C26H23FN6O 454.509000 |
ZVWUPPJKBZWARG-VWLOTQADSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542132; PubChem:CID156054442
|
Local ready
Direct docking supported
|
|
E3L024149
BDB024149
|
US11274090, Example 29 Isomer 2
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cc3F)c3ccccc3)nc2)cn1
|
C26H23FN6O 454.509000 |
ZVWUPPJKBZWARG-RUZDIDTESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542133; PubChem:CID156273028
|
Local ready
Direct docking supported
|
|
E3L024150
BDB024150
|
US11274090, Example 30 Isomer 1
N#Cc1ccc(CCN[C@H](C(=O)Nc2ccn(C3CCOCC3)n2)c2ccccc2)cc1
|
C25H27N5O2 429.524000 |
WIOUJKREADAXHQ-DEOSSOPVSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542134; PubChem:CID156054429
|
Local ready
Direct docking supported
|
|
E3L024151
BDB024151
|
US11274090, Example 30 Isomer 2
N#Cc1ccc(CCN[C@@H](C(=O)Nc2ccn(C3CCOCC3)n2)c2ccccc2)cc1
|
C25H27N5O2 429.524000 |
WIOUJKREADAXHQ-XMMPIXPASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542135; PubChem:CID156273011
|
Local ready
Direct docking supported
|
|
E3L024152
BDB024152
|
US11274090, Example 31 Isomer 1
COC1CN(c2ccc(NC(=O)[C@@H](NCCc3ccc(C#N)cc3)c3ccccc3)nc2)C1
|
C26H27N5O2 441.535000 |
ZPMZVRLAHNQXLU-VWLOTQADSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542136; PubChem:CID155597624
|
Local ready
Direct docking supported
|
|
E3L024153
BDB024153
|
US11274090, Example 31 Isomer 2
COC1CN(c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)nc2)C1
|
C26H27N5O2 441.535000 |
ZPMZVRLAHNQXLU-RUZDIDTESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542137; PubChem:CID156273094
|
Local ready
Direct docking supported
|
|
E3L024154
BDB024154
|
US11274090, Example 32 Isomer 1
COC1CN(c2ccc(NC(=O)[C@H](NC[C@H](C)c3ccc(C#N)cc3)c3ccccc3)nc2)C1
|
C27H29N5O2 455.562000 |
ASGZACULPWEGEE-AFMDSPMNSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542138; PubChem:CID156293368
|
Local ready
Direct docking supported
|
|
E3L024155
BDB024155
|
US11274090, Example 32 Isomer 2
COC1CN(c2ccc(NC(=O)[C@H](NC[C@@H](C)c3ccc(C#N)cc3)c3ccccc3)nc2)C1
|
C27H29N5O2 455.562000 |
ASGZACULPWEGEE-NIYFSFCBSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542139; PubChem:CID156293341
|
Local ready
Direct docking supported
|
|
E3L024156
BDB024156
|
US11274090, Example 32 Isomer 3
COC1CN(c2ccc(NC(=O)[C@@H](NC[C@H](C)c3ccc(C#N)cc3)c3ccccc3)nc2)C1
|
C27H29N5O2 455.562000 |
ASGZACULPWEGEE-SIBVEZHUSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542140; PubChem:CID155597397
|
Local ready
Direct docking supported
|
|
E3L024157
BDB024157
|
US11274090, Example 32 Isomer 4
COC1CN(c2ccc(NC(=O)[C@@H](NC[C@@H](C)c3ccc(C#N)cc3)c3ccccc3)nc2)C1
|
C27H29N5O2 455.562000 |
ASGZACULPWEGEE-BCHFMIIMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542141; PubChem:CID155597355
|
Local ready
Direct docking supported
|
|
E3L024158
BDB024158
|
(R,R)-Cpi-1612
C[C@@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(C)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C27H26N6O 450.546000 |
SEDFZSHSBUXKAC-AFMDSPMNSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542142; PubChem:CID156293396
|
Local ready
Direct docking supported
|
|
E3L024159
BDB024159
|
(R,S)-Cpi-1612
C[C@@H](CN[C@H](C(=O)Nc1ccc(-c2cnn(C)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C27H26N6O 450.546000 |
SEDFZSHSBUXKAC-SIBVEZHUSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542144; PubChem:CID156054448
|
Local ready
Direct docking supported
|
|
E3L024160
BDB024160
|
(S,S)-Cpi-1612
C[C@H](CN[C@H](C(=O)Nc1ccc(-c2cnn(C)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C27H26N6O 450.546000 |
SEDFZSHSBUXKAC-BCHFMIIMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542145; PubChem:CID139426012
|
Local ready
Direct docking supported
|