| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L024421
BDB024421
|
US11274090, Example 140 Isomer 2
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(C(F)(F)F)nc3)c3ccccc3)nc2)cn1
|
C25H23F3N6O 480.494000 |
WTICQEGVYBKMKJ-HSZRJFAPSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542409; PubChem:CID156273099
|
Local ready
Direct docking supported
|
|
E3L024422
BDB024422
|
US11274090, Example 141 Isomer 1
Cc1ccc(CCNC(C(=O)Nc2ccc(-c3cnn(C)c3)cn2)c2ccccc2)cn1
|
C25H26N6O 426.524000 |
CRGKNJMHGQMANQ-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542410; PubChem:CID139425941
|
Local ready
Direct docking supported
|
|
E3L024423
BDB024423
|
US11274090, Example 141 Isomer 2
Cc1ccc(CCN[C@@H](C(=O)Nc2ccc(-c3cnn(C)c3)cn2)c2ccccc2)cn1
|
C25H26N6O 426.524000 |
CRGKNJMHGQMANQ-XMMPIXPASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542411; PubChem:CID156293466
|
Local ready
Direct docking supported
|
|
E3L024424
BDB024424
|
US11274090, Example 142 Isomer 1
Cn1cc(-c2ccc(NC(=O)[C@@H](NCCc3ccc(C#N)cn3)c3ccccc3)nc2)cn1
|
C25H23N7O 437.507000 |
IGCPOWGYRDEVGB-DEOSSOPVSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542412; PubChem:CID139426082
|
Local ready
Direct docking supported
|
|
E3L024425
BDB024425
|
US11274090, Example 142 Isomer 2
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(C#N)cn3)c3ccccc3)nc2)cn1
|
C25H23N7O 437.507000 |
IGCPOWGYRDEVGB-XMMPIXPASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542413; PubChem:CID156273074
|
Local ready
Direct docking supported
|
|
E3L024426
BDB024426
|
US11274090, Example 143 Isomer 1
Cc1ccc([C@@H](C)CN[C@@H](C(=O)Nc2ccc(-c3cnn(C)c3)cn2)c2ccccc2)cn1
|
C26H28N6O 440.551000 |
IRFYMUZAFSCZFS-AVRWGWEMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542414; PubChem:CID156293453
|
Local ready
Direct docking supported
|
|
E3L024427
BDB024427
|
US11274090, Example 143 Isomer 2
Cc1ccc([C@H](C)CN[C@@H](C(=O)Nc2ccc(-c3cnn(C)c3)cn2)c2ccccc2)cn1
|
C26H28N6O 440.551000 |
IRFYMUZAFSCZFS-IQGLISFBSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542415; PubChem:CID156293454
|
Local ready
Direct docking supported
|
|
E3L024428
BDB024428
|
US11274090, Example 143 Isomer 3
Cc1ccc([C@@H](C)CN[C@H](C(=O)Nc2ccc(-c3cnn(C)c3)cn2)c2ccccc2)cn1
|
C26H28N6O 440.551000 |
IRFYMUZAFSCZFS-BVZFJXPGSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542416; PubChem:CID139426085
|
Local ready
Direct docking supported
|
|
E3L024429
BDB024429
|
US11274090, Example 143 Isomer 4
Cc1ccc([C@H](C)CN[C@H](C(=O)Nc2ccc(-c3cnn(C)c3)cn2)c2ccccc2)cn1
|
C26H28N6O 440.551000 |
IRFYMUZAFSCZFS-CJAUYULYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542417; PubChem:CID139426074
|
Local ready
Direct docking supported
|
|
E3L024430
BDB024430
|
US11274090, Example 144 Isomer 1
Cn1cc(-c2ccc(NC(=O)[C@@H](NCCn3cc(C#N)cn3)c3ccccc3)nc2)cn1
|
C23H22N8O 426.484000 |
SDKDIYYEBIDJAC-QFIPXVFZSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542418; PubChem:CID139426089
|
Local ready
Direct docking supported
|
|
E3L024431
BDB024431
|
US11274090, Example 144 Isomer 2
Cn1cc(-c2ccc(NC(=O)[C@H](NCCn3cc(C#N)cn3)c3ccccc3)nc2)cn1
|
C23H22N8O 426.484000 |
SDKDIYYEBIDJAC-JOCHJYFZSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542419; PubChem:CID156273009
|
Local ready
Direct docking supported
|
|
E3L024432
BDB024432
|
US11274090, Example 145 Isomer 1
Cc1cc(C#N)nn1CCN[C@H](C(=O)Nc1ccc(-c2cnn(C)c2)cn1)c1ccccc1
|
C24H24N8O 440.511000 |
AUSABBMVHMAYOV-QHCPKHFHSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542420; PubChem:CID139426086
|
Local ready
Direct docking supported
|
|
E3L024433
BDB024433
|
US11274090, Example 145 Isomer 2
Cc1cc(C#N)nn1CCN[C@@H](C(=O)Nc1ccc(-c2cnn(C)c2)cn1)c1ccccc1
|
C24H24N8O 440.511000 |
AUSABBMVHMAYOV-HSZRJFAPSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542421; PubChem:CID156273020
|
Local ready
Direct docking supported
|
|
E3L024434
BDB024434
|
US11274090, Example 146 Isomer 1
CNC(=O)Cn1cc(-c2ccc(NC(=O)[C@H](NC[C@H](C)c3ccc(C#N)cc3)c3ccccc3)nc2)cn1
|
C29H29N7O2 507.598000 |
IZDVOEWRWQYODV-WTYVLRPYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542422; PubChem:CID164515111
|
Local ready
Direct docking supported
|
|
E3L024435
BDB024435
|
US11274090, Example 146 Isomer 2
CNC(=O)Cn1cc(-c2ccc(NC(=O)[C@H](NC[C@@H](C)c3ccc(C#N)cc3)c3ccccc3)nc2)cn1
|
C29H29N7O2 507.598000 |
IZDVOEWRWQYODV-PIIWDFAUSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542423; PubChem:CID156293350
|
Local ready
Direct docking supported
|
|
E3L024436
BDB024436
|
US11274090, Example 147 Isomer 1
C[C@@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(CC(N)=O)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C28H27N7O2 493.571000 |
IIXBGTHNXZYSGX-UZTOHYMASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542424; PubChem:CID164515112
|
Local ready
Direct docking supported
|
|
E3L024437
BDB024437
|
US11274090, Example 147 Isomer 2
C[C@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(CC(N)=O)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C28H27N7O2 493.571000 |
IIXBGTHNXZYSGX-XHCCPWGMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542425; PubChem:CID156293351
|
Local ready
Direct docking supported
|
|
E3L024438
BDB024438
|
US11274090, Example 148 Isomer 1
Cn1cc(-c2ccc(NC(=O)[C@@H](NCCc3ccc(Cl)cc3)c3cnn(C)c3)nc2)cn1
|
C23H24ClN7O 449.946000 |
VOYCPNMDRSYGMC-QFIPXVFZSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542426; PubChem:CID164515113
|
Local ready
Direct docking supported
|
|
E3L024439
BDB024439
|
US11274090, Example 148 Isomer 2
Cn1cc(-c2ccc(NC(=O)[C@H](NCCc3ccc(Cl)cc3)c3cnn(C)c3)nc2)cn1
|
C23H24ClN7O 449.946000 |
VOYCPNMDRSYGMC-JOCHJYFZSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542427; PubChem:CID156273097
|
Local ready
Direct docking supported
|
|
E3L024440
BDB024440
|
US11274090, Example 149 Isomer 1
Cn1cc(-c2ccc(NC(=O)[C@@H](NCC(c3ccc(C#N)cc3)C(F)(F)F)c3ccccc3)nc2)cn1
|
C27H23F3N6O 504.516000 |
OOKDMDYSGMQNGA-YNMFNDETSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542428; PubChem:CID156273092
|
Local ready
Direct docking supported
|