| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L024401
BDB024401
|
US11274090, Example 131 Isomer 2
Cc1noc(C)c1-c1ccc(NC(=O)[C@H](NC[C@@H](C)c2ccc(C#N)cc2)c2ccccc2)nc1
|
C28H27N5O2 465.557000 |
GNTXDLSEJCXETJ-DNOBIOAJSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542389; PubChem:CID156293918
|
Local ready
Direct docking supported
|
|
E3L024402
BDB024402
|
US11274090, Example 132 Isomer 1
C[C@@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(CC(=O)N3CCCC3)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C32H33N7O2 547.663000 |
OHGJQTVLKQXBIW-GTYOFVGBSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542390; PubChem:CID164515101
|
Local ready
Direct docking supported
|
|
E3L024403
BDB024403
|
US11274090, Example 132 Isomer 2
C[C@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(CC(=O)N3CCCC3)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C32H33N7O2 547.663000 |
OHGJQTVLKQXBIW-SLGOVJDISA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542391; PubChem:CID164515102
|
Local ready
Direct docking supported
|
|
E3L024404
BDB024404
|
US11274090, Example 133 Isomer 1
Cc1n[nH]c(C)c1-c1ccc(NC(=O)[C@H](NC[C@H](C)c2ccc(C#N)cc2)c2ccccc2)nc1
|
C28H28N6O 464.573000 |
WWWOMSXOMMVHOG-XRHLQHRESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542392; PubChem:CID164515103
|
Local ready
Direct docking supported
|
|
E3L024405
BDB024405
|
US11274090, Example 133 Isomer 2
Cc1n[nH]c(C)c1-c1ccc(NC(=O)[C@H](NC[C@@H](C)c2ccc(C#N)cc2)c2ccccc2)nc1
|
C28H28N6O 464.573000 |
WWWOMSXOMMVHOG-DNOBIOAJSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542393; PubChem:CID156293433
|
Local ready
Direct docking supported
|
|
E3L024406
BDB024406
|
US11274090, Example 134 Isomer 1
C[C@@H](CN[C@@H](C(=O)Nc1ccc(-c2ccc(=O)n(C)n2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C28H26N6O2 478.556000 |
LPHBTWNESNVVOF-UZTOHYMASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542394; PubChem:CID164515104
|
Local ready
Direct docking supported
|
|
E3L024407
BDB024407
|
US11274090, Example 134 Isomer 2
C[C@H](CN[C@@H](C(=O)Nc1ccc(-c2ccc(=O)n(C)n2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C28H26N6O2 478.556000 |
LPHBTWNESNVVOF-XHCCPWGMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542395; PubChem:CID156293435
|
Local ready
Direct docking supported
|
|
E3L024408
BDB024408
|
US11274090, Example 135 Isomer 1
CC(=O)N1CCN(c2ccc(NC(=O)[C@H](NC[C@H](C)c3ccc(C#N)cc3)c3cccc(F)c3)nc2)CC1
|
C29H31FN6O2 514.605000 |
QWAWGAHBJXOAPI-WTYVLRPYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542396; PubChem:CID164515105
|
Local ready
Direct docking supported
|
|
E3L024409
BDB024409
|
US11274090, Example 135 Isomer 2
CC(=O)N1CCN(c2ccc(NC(=O)[C@H](NC[C@@H](C)c3ccc(C#N)cc3)c3cccc(F)c3)nc2)CC1
|
C29H31FN6O2 514.605000 |
QWAWGAHBJXOAPI-PIIWDFAUSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542397; PubChem:CID156293352
|
Local ready
Direct docking supported
|
|
E3L024410
BDB024410
|
US11274090, Example 136 Isomer 1
C[C@@H](CN[C@@H](C(=O)Nc1ccc(N2CCN(C)C(=O)C2)cn1)c1cnn(C)c1)c1ccc(C#N)cc1
|
C26H30N8O2 486.580000 |
STRXYQWDVXGLBM-AVRWGWEMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542398; PubChem:CID156293359
|
Local ready
Direct docking supported
|
|
E3L024411
BDB024411
|
US11274090, Example 136 Isomer 2
C[C@H](CN[C@@H](C(=O)Nc1ccc(N2CCN(C)C(=O)C2)cn1)c1cnn(C)c1)c1ccc(C#N)cc1
|
C26H30N8O2 486.580000 |
STRXYQWDVXGLBM-IQGLISFBSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542399; PubChem:CID156293358
|
Local ready
Direct docking supported
|
|
E3L024412
BDB024412
|
US11274090, Example 136 Isomer 3
C[C@@H](CN[C@H](C(=O)Nc1ccc(N2CCN(C)C(=O)C2)cn1)c1cnn(C)c1)c1ccc(C#N)cc1
|
C26H30N8O2 486.580000 |
STRXYQWDVXGLBM-BVZFJXPGSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542400; PubChem:CID164515106
|
Local ready
Direct docking supported
|
|
E3L024413
BDB024413
|
US11274090, Example 136 Isomer 4
C[C@H](CN[C@H](C(=O)Nc1ccc(N2CCN(C)C(=O)C2)cn1)c1cnn(C)c1)c1ccc(C#N)cc1
|
C26H30N8O2 486.580000 |
STRXYQWDVXGLBM-CJAUYULYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542401; PubChem:CID139425877
|
Local ready
Direct docking supported
|
|
E3L024414
BDB024414
|
US11274090, Example 137 Isomer 1
C[C@@H](CN[C@@H](C(=O)Nc1ccc(N2CCN(C)C(=O)C2)cn1)c1cccc(F)c1)c1ccc(C#N)cc1
|
C28H29FN6O2 500.578000 |
NZWWUOFAPFARQI-UZTOHYMASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542402; PubChem:CID164515107
|
Local ready
Direct docking supported
|
|
E3L024415
BDB024415
|
US11274090, Example 137 Isomer 2
C[C@H](CN[C@@H](C(=O)Nc1ccc(N2CCN(C)C(=O)C2)cn1)c1cccc(F)c1)c1ccc(C#N)cc1
|
C28H29FN6O2 500.578000 |
NZWWUOFAPFARQI-XHCCPWGMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542403; PubChem:CID164515108
|
Local ready
Direct docking supported
|
|
E3L024416
BDB024416
|
US11274090, Example 138 Isomer 1
C[C@@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(CC(=O)N(C)C)c2)cn1)c1cccc(F)c1)c1ccc(C#N)cc1
|
C30H30FN7O2 539.615000 |
FXMFMIDHVXZKJV-AFJIDDCJSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542404; PubChem:CID164515109
|
Local ready
Direct docking supported
|
|
E3L024417
BDB024417
|
US11274090, Example 138 Isomer 2
C[C@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(CC(=O)N(C)C)c2)cn1)c1cccc(F)c1)c1ccc(C#N)cc1
|
C30H30FN7O2 539.615000 |
FXMFMIDHVXZKJV-ACSYHNTCSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542405; PubChem:CID156293913
|
Local ready
Direct docking supported
|
|
E3L024418
BDB024418
|
US11274090, Example 139 Isomer 1
C[C@@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(C)c(=O)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C28H26N6O2 478.556000 |
RGZOWTHKYIUCTR-UZTOHYMASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542406; PubChem:CID164515110
|
Local ready
Direct docking supported
|
|
E3L024419
BDB024419
|
US11274090, Example 139 Isomer 2
C[C@H](CN[C@@H](C(=O)Nc1ccc(-c2cnn(C)c(=O)c2)cn1)c1ccccc1)c1ccc(C#N)cc1
|
C28H26N6O2 478.556000 |
RGZOWTHKYIUCTR-XHCCPWGMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542407; PubChem:CID156293912
|
Local ready
Direct docking supported
|
|
E3L024420
BDB024420
|
US11274090, Example 140 Isomer 1
Cn1cc(-c2ccc(NC(=O)[C@@H](NCCc3ccc(C(F)(F)F)nc3)c3ccccc3)nc2)cn1
|
C25H23F3N6O 480.494000 |
WTICQEGVYBKMKJ-QHCPKHFHSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM542408; PubChem:CID139426071
|
Local ready
Direct docking supported
|