| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027101
BDB027101
|
US11414384, Example 153 Isomer 2
CN(C)CCNC(=O)c1ccc2c(C(=O)[C@@H](NCCc3ccc(Cl)cc3Cl)c3ccccc3)c[nH]c2c1
|
C29H30Cl2N4O2 537.491000 |
CYSITNKCPSLBOI-MHZLTWQESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564575; PubChem:CID156133933
|
Local ready
Direct docking supported
|
|
E3L027102
BDB027102
|
US11414384, Example 154 Isomer 1
COCCNC(=O)c1ccc2c(C(=O)C(NCCc3ccc(Cl)cc3Cl)c3ccccc3)c[nH]c2c1
|
C28H27Cl2N3O3 524.448000 |
LPKXYLWCUWTAKO-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564576; PubChem:CID139422879
|
Local ready
Direct docking supported
|
|
E3L027103
BDB027103
|
US11414384, Example 155 Isomer 1
N#Cc1ccc(CCN[C@H](C(=O)c2c[nH]c3cc(C(=O)O)ccc23)c2ccccc2)cc1
|
C26H21N3O3 423.472000 |
AIGUDHMFUUPJMH-DEOSSOPVSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564578; PubChem:CID156133931
|
Local ready
Direct docking supported
|
|
E3L027104
BDB027104
|
US11414384, Example 155 Isomer 2
N#Cc1ccc(CCN[C@@H](C(=O)c2c[nH]c3cc(C(=O)O)ccc23)c2ccccc2)cc1
|
C26H21N3O3 423.472000 |
AIGUDHMFUUPJMH-XMMPIXPASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564579; PubChem:CID156114976
|
Local ready
Direct docking supported
|
|
E3L027105
BDB027105
|
US11414384, Example 156 Isomer 1
CNC(=O)c1ccc2c(C(=O)[C@@H](NCCc3ccc(C#N)cc3)c3ccccc3)c[nH]c2c1
|
C27H24N4O2 436.515000 |
IZZTWVMVWVZFDU-VWLOTQADSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564581; PubChem:CID156132179
|
Local ready
Direct docking supported
|
|
E3L027106
BDB027106
|
US11414384, Example 156 Isomer 2
CNC(=O)c1ccc2c(C(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)c[nH]c2c1
|
C27H24N4O2 436.515000 |
IZZTWVMVWVZFDU-RUZDIDTESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564582; PubChem:CID156114879
|
Local ready
Direct docking supported
|
|
E3L027107
BDB027107
|
US11414384, Example 157 Isomer 1
N#Cc1ccc(CCN[C@H](C(=O)c2c[nH]c3cc(C(=O)NCC(F)(F)F)ccc23)c2ccccc2)cc1
|
C28H23F3N4O2 504.512000 |
VJAWCSZJCQCSII-VWLOTQADSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564585; PubChem:CID156132180
|
Local ready
Direct docking supported
|
|
E3L027108
BDB027108
|
US11414384, Example 157 Isomer 2
N#Cc1ccc(CCN[C@@H](C(=O)c2c[nH]c3cc(C(=O)NCC(F)(F)F)ccc23)c2ccccc2)cc1
|
C28H23F3N4O2 504.512000 |
VJAWCSZJCQCSII-RUZDIDTESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564588; PubChem:CID156114978
|
Local ready
Direct docking supported
|
|
E3L027109
BDB027109
|
US11414384, Example 158 Isomer 1
CNC(=O)CCc1ccc2c(C(=O)[C@H](NCCc3ccc(F)cc3)c3ccccc3)c[nH]c2c1
|
C28H28FN3O2 457.549000 |
OJUAXTSISICNFB-HHHXNRCGSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564589; PubChem:CID156114869
|
Local ready
Direct docking supported
|
|
E3L027110
BDB027110
|
US11414384, Example 158 Isomer 2
CNC(=O)CCc1ccc2c(C(=O)[C@@H](NCCc3ccc(F)cc3)c3ccccc3)c[nH]c2c1
|
C28H28FN3O2 457.549000 |
OJUAXTSISICNFB-MHZLTWQESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564590; PubChem:CID156132181
|
Local ready
Direct docking supported
|
|
E3L027111
BDB027111
|
US11414384, Example 159 Isomer 1
O=C(O)CCc1ccc2c(C(=O)[C@H](NCCc3ccc(F)cc3)c3ccccc3)c[nH]c2c1
|
C27H25FN2O3 444.506000 |
DHJSJWATKMCMBD-AREMUKBSSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564591; PubChem:CID156115011
|
Local ready
Direct docking supported
|
|
E3L027112
BDB027112
|
US11414384, Example 159 Isomer 2
O=C(O)CCc1ccc2c(C(=O)[C@@H](NCCc3ccc(F)cc3)c3ccccc3)c[nH]c2c1
|
C27H25FN2O3 444.506000 |
DHJSJWATKMCMBD-SANMLTNESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564593; PubChem:CID156133608
|
Local ready
Direct docking supported
|
|
E3L027113
BDB027113
|
US11414384, Example 160 Isomer 1
N#Cc1ccc(CCN[C@H](C(=O)c2c[nH]c3cc(CC(=O)O)ccc23)c2ccccc2)cc1
|
C27H23N3O3 437.499000 |
VZAHDAUTUNFMIV-SANMLTNESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564595; PubChem:CID139422759
|
Local ready
Direct docking supported
|
|
E3L027114
BDB027114
|
US11414384, Example 160 Isomer 2
N#Cc1ccc(CCN[C@@H](C(=O)c2c[nH]c3cc(CC(=O)O)ccc23)c2ccccc2)cc1
|
C27H23N3O3 437.499000 |
VZAHDAUTUNFMIV-AREMUKBSSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564596; PubChem:CID156133610
|
Local ready
Direct docking supported
|
|
E3L027115
BDB027115
|
US11414384, Example 161 Isomer 1
CC(C)(O)CNC(=O)c1ccc2c(C(=O)[C@@H](NCCc3ccc(C#N)cc3)c3ccccc3)c[nH]c2c1
|
C30H30N4O3 494.595000 |
ZXNRDVKXEACFMY-MHZLTWQESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564598; PubChem:CID139422820
|
Local ready
Direct docking supported
|
|
E3L027116
BDB027116
|
US11414384, Example 161 Isomer 2
CC(C)(O)CNC(=O)c1ccc2c(C(=O)[C@H](NCCc3ccc(C#N)cc3)c3ccccc3)c[nH]c2c1
|
C30H30N4O3 494.595000 |
ZXNRDVKXEACFMY-HHHXNRCGSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564599; PubChem:CID156114830
|
Local ready
Direct docking supported
|
|
E3L027117
BDB027117
|
US11414384, Example 162 Isomer 1
N#Cc1ccc(CCN[C@H](C(=O)c2c[nH]c3cc(C(=O)NC4CN(CC(F)(F)F)C4)ccc23)c2ccccc2)cc1
|
C31H28F3N5O2 559.592000 |
AIGITZYSZNQTRP-NDEPHWFRSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564602; PubChem:CID139422977
|
Local ready
Direct docking supported
|
|
E3L027118
BDB027118
|
US11414384, Example 162 Isomer 2
N#Cc1ccc(CCN[C@@H](C(=O)c2c[nH]c3cc(C(=O)NC4CN(CC(F)(F)F)C4)ccc23)c2ccccc2)cc1
|
C31H28F3N5O2 559.592000 |
AIGITZYSZNQTRP-MUUNZHRXSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564604; PubChem:CID156114813
|
Local ready
Direct docking supported
|
|
E3L027119
BDB027119
|
US11414384, Example 163 Isomer 1
CCN1CC(NC(=O)c2ccc3c(C(=O)[C@@H](NCCc4ccc(C#N)cc4)c4ccccc4)c[nH]c3c2)C1
|
C31H31N5O2 505.622000 |
QRJDVDGASZQWKH-LJAQVGFWSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564605; PubChem:CID139422978
|
Local ready
Direct docking supported
|
|
E3L027120
BDB027120
|
US11414384, Example 163 Isomer 2
CCN1CC(NC(=O)c2ccc3c(C(=O)[C@H](NCCc4ccc(C#N)cc4)c4ccccc4)c[nH]c3c2)C1
|
C31H31N5O2 505.622000 |
QRJDVDGASZQWKH-GDLZYMKVSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM564608; PubChem:CID156114842
|
Local ready
Direct docking supported
|