| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027461
BDB027461
|
US11420970, Example 283
Cn1ncc([C@H]2CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)nccc43)C2)n1
|
C26H25F2N9 501.545000 |
JQQQSMNMDBQWRG-KRWDZBQOSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568081; PubChem:CID164850538
|
Local ready
Direct docking supported
|
|
E3L027462
BDB027462
|
US11420970, Example 284
Cc1cc([C@@]2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)no1
|
C26H25F2N9O 517.544000 |
GLNYSDHRUSRCGS-AREMUKBSSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568082; PubChem:CID156073212
|
Local ready
Direct docking supported
|
|
E3L027463
BDB027463
|
US11420970, Example 285
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)([C@@H](F)CO)C1
|
C24H25F3N8O 498.513000 |
ADORMPJFMOADGA-GBXCKJPGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568083; PubChem:CID156073184
|
Local ready
Direct docking supported
|
|
E3L027464
BDB027464
|
US11420970, Example 286
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(F)cc2F)ncc1N1CCC[C@](N)([C@@H](F)CO)C1
|
C24H24F4N8O 516.503000 |
PUQMTRGYMNBENI-GBXCKJPGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568084; PubChem:CID156073396
|
Local ready
Direct docking supported
|
|
E3L027465
BDB027465
|
US11420970, Example 287
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(C(F)CF)C1
|
C24H24F4N8 500.504000 |
XRQVIJMOYCCWCL-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568085; PubChem:CID156073189
|
Local ready
Direct docking supported
|
|
E3L027466
BDB027466
|
US11420970, Example 288
C[C@H]1COC[C@@H]([C@@]2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)O1
|
C27H30F2N8O2 536.587000 |
VLZDKMNEISVRGM-HNVUPHGUSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568086; PubChem:CID156073182
|
Local ready
Direct docking supported
|
|
E3L027467
BDB027467
|
US11420970, Example 290
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(F)cc2F)ncc1N1CCC[C@](N)([C@@H]2COCCO2)C1
|
C26H27F3N8O2 540.550000 |
YKSCTELKTAJQDM-BKMJKUGQSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568088; PubChem:CID156073191
|
Local ready
Direct docking supported
|
|
E3L027468
BDB027468
|
US11420970, Example 291
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(F)cc2C(F)F)ncc1N1CCC[C@](N)([C@@H]2COCCO2)C1
|
C27H28F4N8O2 572.567000 |
XAAIPOMVFOYMRY-WXVAWEFUSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568089; PubChem:CID156073336
|
Local ready
Direct docking supported
|
|
E3L027469
BDB027469
|
US11420970, Example 292
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@]2(COC(=O)N2)C1
|
C24H22F2N8O2 492.490000 |
WVXYRHIQASBBFS-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568090; PubChem:CID156073340
|
Local ready
Direct docking supported
|
|
E3L027470
BDB027470
|
US11420970, Example 293
CC(=C(F)F)[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C25H24F4N8 512.515000 |
IVJCMXAPDDHEHS-RUZDIDTESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568091; PubChem:CID156073337
|
Local ready
Direct docking supported
|
|
E3L027471
BDB027471
|
US11420970, Example 294
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(C=C(F)F)C1
|
C24H22F4N8 498.488000 |
ZGRFJQPQQHGGAX-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568092; PubChem:CID156073339
|
Local ready
Direct docking supported
|
|
E3L027472
BDB027472
|
US11420970, Example 295
COc1ccc(C2C=C(Cn3cnc4c(N)ncnc43)C(N3CCCC(N)(C(C)F)C3)=CN2)cc1F
|
C25H30F2N8O 496.566000 |
QYFYWHODLJRKKW-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568093; PubChem:CID164850522
|
Local ready
Direct docking supported
|
|
E3L027473
BDB027473
|
US11420970, Example 296
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@@H](N)[C@@H]1Cn1cccn1
|
C26H26F2N10 516.560000 |
LCWKRPIOOKKOBC-OFNKIYASSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568094; PubChem:CID164850544
|
Local ready
Direct docking supported
|
|
E3L027474
BDB027474
|
US11420970, Example 297
CSCC1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C24H26F2N8S 496.591000 |
GREXWDCNJSPLDM-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568095; PubChem:CID164850526
|
Local ready
Direct docking supported
|
|
E3L027475
BDB027475
|
US11420970, Example 298
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)([C@H](O)C(F)(F)F)C1
|
C24H23F5N8O 534.493000 |
HALGWYFQGMHNJR-XZOQPEGZSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568096; PubChem:CID156073354
|
Local ready
Direct docking supported
|
|
E3L027476
BDB027476
|
US11420970, Example 300
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(C(F)C(F)(F)F)C1
|
C24H22F6N8 536.484000 |
DEBIKFNEKDBSOC-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568098; PubChem:CID164850534
|
Local ready
Direct docking supported
|
|
E3L027477
BDB027477
|
US11420970, Example 301
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC(O)C(N)(CC(F)F)C1
|
C24H24F4N8O 516.503000 |
HNHPSIVSOKXOFE-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568099; PubChem:CID156067100
|
Local ready
Direct docking supported
|
|
E3L027478
BDB027478
|
US11420970, Example 302
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CC[C@@H](O)[C@](N)(c2cccc(Cl)n2)C1
|
C27H24ClF2N9O 564.000000 |
BRJYJJXPWLLDRE-AJTFRIOCSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568100; PubChem:CID156073298
|
Local ready
Direct docking supported
|
|
E3L027479
BDB027479
|
US11420970, Example 303
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(CC(F)(F)F)C3)cn2)cc1F
|
C25H26F4N8O 530.530000 |
KONFTSZTQMVPLD-DEOSSOPVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568101; PubChem:CID156073300
|
Local ready
Direct docking supported
|
|
E3L027480
BDB027480
|
US11420970, Example 304
C#C[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C24H22F2N8 460.492000 |
DNTICLPLUMTLSR-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568102; PubChem:CID156073299
|
Local ready
Direct docking supported
|