| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027481
BDB027481
|
US11420970, Example 305
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(C(F)F)C3)cn2)cc1F
|
C24H25F3N8O 498.513000 |
FNVOPHQMLFXCMY-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568103; PubChem:CID164850505
|
Local ready
Direct docking supported
|
|
E3L027482
BDB027482
|
US11420970, Example 306
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3C[C@H](N)C[C@@H](CF)C3)cn2)cc1F
|
C24H26F2N8O 480.523000 |
XCNOJYKALJIDBQ-WMLDXEAASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568104; PubChem:CID156069954
|
Local ready
Direct docking supported
|
|
E3L027483
BDB027483
|
US11420970, Example 307
C[C@@H]1CN(c2cnc(-c3ccc(F)cc3)cc2Cn2cnc3c(N)ncnc32)C[C@@](N)(CC(F)F)C1
|
C25H27F3N8 496.541000 |
QIRXUANSYDMCGC-MQNRADLISA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568105; PubChem:CID156073137
|
Local ready
Direct docking supported
|
|
E3L027484
BDB027484
|
US11420970, Example 308
COCC1CC(N)CN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C24H26F2N8O 480.523000 |
GRRNWTVHLNOABN-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568106; PubChem:CID164850552
|
Local ready
Direct docking supported
|
|
E3L027485
BDB027485
|
US11420970, Example 309
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1C[C@H](N)C[C@H](F)C1
|
C22H21F3N8 454.460000 |
ZPRIUHCMMVNBPP-LSDHHAIUSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568107; PubChem:CID156073134
|
Local ready
Direct docking supported
|
|
E3L027486
BDB027486
|
US11420970, Example 310
C[C@H]1CC[C@@H](N)CN1c1cnc(-c2ccc(F)c(F)c2)cc1Cn1cnc2c(N)ncnc21
|
C23H24F2N8 450.497000 |
GAFBETZZVZMNAO-XJKSGUPXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568108; PubChem:CID156073136
|
Local ready
Direct docking supported
|
|
E3L027487
BDB027487
|
US11420970, Example 311
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@@H](N)[C@H]1COC(F)F
|
C24H24F4N8O 516.503000 |
YSUREOCRJSILPY-YLJYHZDGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568109; PubChem:CID156073459
|
Local ready
Direct docking supported
|
|
E3L027488
BDB027488
|
US11420970, Example 312
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@@H](N)[C@H]1CO
|
C23H24F2N8O 466.496000 |
YROMIJBJXSMXHY-YLJYHZDGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568110; PubChem:CID156073460
|
Local ready
Direct docking supported
|
|
E3L027489
BDB027489
|
US11420970, Example 313
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@@H](N)[C@H]1COCC(F)F
|
C25H26F4N8O 530.530000 |
RAEHGKQNHSTYNV-WIYYLYMNSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568111; PubChem:CID156073461
|
Local ready
Direct docking supported
|
|
E3L027490
BDB027490
|
US11420970, Example 314
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@@H](N)[C@H]1CCO
|
C24H26F2N8O 480.523000 |
WDUCEZOTCKEVMG-UYAOXDASSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568112; PubChem:CID156073458
|
Local ready
Direct docking supported
|
|
E3L027491
BDB027491
|
US11420970, Example 315
CNC(=O)[C@@H]1[C@H](N)CCCN1c1cnc(-c2ccc(F)c(F)c2)cc1Cn1cnc2c(N)ncnc21
|
C24H25F2N9O 493.522000 |
CXPQVLFAFLLWRT-UTKZUKDTSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568113; PubChem:CID156073457
|
Local ready
Direct docking supported
|
|
E3L027492
BDB027492
|
US11420970, Example 316
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@@H](N)[C@H]1C(O)C(F)(F)F
|
C24H23F5N8O 534.493000 |
FIHONNHTLHRHPU-DPVFXHEMSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568114; PubChem:CID164850554
|
Local ready
Direct docking supported
|
|
E3L027493
BDB027493
|
US11420970, Example 317
CN(C)C(=O)[C@@H]1[C@H](N)CCCN1c1cnc(-c2ccc(F)c(F)c2)cc1Cn1cnc2c(N)ncnc21
|
C25H27F2N9O 507.549000 |
GBHLVFCGDXRFRE-GCJKJVERSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568115; PubChem:CID156073330
|
Local ready
Direct docking supported
|
|
E3L027494
BDB027494
|
US11420970, Example 318
NC(=O)[C@@H]1[C@H](N)CCCN1c1cnc(-c2ccc(F)c(F)c2)cc1Cn1cnc2c(N)ncnc21
|
C23H23F2N9O 479.495000 |
HXEOVCBFLIZDEK-UZLBHIALSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568116; PubChem:CID156073328
|
Local ready
Direct docking supported
|
|
E3L027495
BDB027495
|
US11420970, Example 319
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@@H](N)[C@H]1C(=O)O
|
C23H22F2N8O2 480.479000 |
URIWUYOVRXDHKH-UZLBHIALSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568117; PubChem:CID156073334
|
Local ready
Direct docking supported
|
|
E3L027496
BDB027496
|
US11420970, Example 320
NC(=O)C[C@@H]1[C@H](N)CCCN1c1cnc(-c2ccc(F)c(F)c2)cc1Cn1cnc2c(N)ncnc21
|
C24H25F2N9O 493.522000 |
GVYRECWJRXNFOH-IEBWSBKVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568118; PubChem:CID164850527
|
Local ready
Direct docking supported
|
|
E3L027497
BDB027497
|
US11420970, Example 321
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC2(COCCN2)C1
|
C25H26F2N8O 492.534000 |
ZBXLWPINSLWPEA-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568119; PubChem:CID156073367
|
Local ready
Direct docking supported
|
|
E3L027498
BDB027498
|
US11420970, Example 322
CN(C)C(=O)CC[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C27H31F2N9O 535.603000 |
VCUOTECLGKIUBH-MHZLTWQESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568120; PubChem:CID156067104
|
Local ready
Direct docking supported
|
|
E3L027499
BDB027499
|
US11420970, Example 323
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@@H](N)[C@H]1c1ccccc1
|
C28H26F2N8 512.568000 |
KPSDKESAHDZHDC-ATIYNZHBSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568121; PubChem:CID156073422
|
Local ready
Direct docking supported
|
|
E3L027500
BDB027500
|
US11420970, Example 324
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)C1=O
|
C22H20F2N8O 450.453000 |
ZAQVDDMYYRTZDL-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568122; PubChem:CID156073465
|
Local ready
Direct docking supported
|