| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027781
BDB027781
|
US11458138, Example 181
Cc1cc(-c2nc(NC3(C)CC3)c3ccncc3n2)on1
|
C15H15N5O 281.319000 |
XZHFDPRSPNKPKS-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574352; PubChem:CID135368309
|
Local ready
Direct docking supported
|
|
E3L027782
BDB027782
|
US11458138, Example 182
CC1(Nc2nc(-c3nn[nH]n3)nc3cnccc23)CC1
|
C12H12N8 268.284000 |
VBRSIZGFUHKGKX-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574353; PubChem:CID137350640
|
Local ready
Direct docking supported
|
|
E3L027783
BDB027783
|
BDBM574354
CC(Nc1nc(-c2cn[nH]c2)nc2cnccc12)c1ccncc1
|
C17H15N7 317.356000 |
IMKBLHYHDBBTHT-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574354; PubChem:CID135368733
|
Local ready
Direct docking supported
|
|
E3L027784
BDB027784
|
US11458138, Example 184
Cn1nccc1-c1nc(NC(C)(C)C)c2ccncc2n1
|
C15H18N6 282.351000 |
JOTDGVJXVZVRAJ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574355; PubChem:CID137350742
|
Local ready
Direct docking supported
|
|
E3L027785
BDB027785
|
US11458138, Example 185
Cc1n[nH]cc1-c1nc(NC2(CO)CCC2)c2ccncc2n1
|
C16H18N6O 310.361000 |
RZIMAHVXUWVICF-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574356; PubChem:CID135368685
|
Local ready
Direct docking supported
|
|
E3L027786
BDB027786
|
US11458138, Example 186
Cn1nccc1-c1nc(NC2(C)CCC2)c2ccncc2n1
|
C16H18N6 294.362000 |
ZFZNIZVNKXAOHL-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574357; PubChem:CID137350734
|
Local ready
Direct docking supported
|
|
E3L027787
BDB027787
|
US11458138, Example 187
Cn1nccc1-c1nc(NC2(CO)CCC2)c2ccncc2n1
|
C16H18N6O 310.361000 |
HAPMHUJZLOBAFY-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574358; PubChem:CID135368373
|
Local ready
Direct docking supported
|
|
E3L027788
BDB027788
|
US11458138, Example 188
FC(F)(F)C1(Nc2nc(-c3cn[nH]c3)nc3cnccc23)CC1
|
C14H11F3N6 320.278000 |
RONGILKHEPYBQB-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574359; PubChem:CID135368388
|
Local ready
Direct docking supported
|
|
E3L027789
BDB027789
|
US11458138, Example 189
Cn1nccc1-c1nc(NC2(C(F)(F)F)CC2)c2ccncc2n1
|
C15H13F3N6 334.305000 |
YWDJQEQIHYKMIP-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574360; PubChem:CID135368046
|
Local ready
Direct docking supported
|
|
E3L027790
BDB027790
|
BDBM574361
Cc1n[nH]cc1-c1nc(NC(C)c2ccncc2)c2ccncc2n1
|
C18H17N7 331.383000 |
RZYNULLUQNFUKK-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574361; PubChem:CID137351085
|
Local ready
Direct docking supported
|
|
E3L027791
BDB027791
|
US11458138, Example 191
OCC1(Nc2nc(-c3cn[nH]c3)nc3cnccc23)CCC1
|
C15H16N6O 296.334000 |
VLQFNIPXKQATHS-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574362; PubChem:CID137350485
|
Local ready
Direct docking supported
|
|
E3L027792
BDB027792
|
US11458138, Example 192
OCC1(Nc2nc(-c3cn[nH]c3)nc3cnccc23)CC1
|
C14H14N6O 282.307000 |
OCPJMPLZBZQYJM-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574363; PubChem:CID135390678
|
Local ready
Direct docking supported
|
|
E3L027793
BDB027793
|
US11458138, Example 193
CC(Nc1nc(-c2ccnn2C)nc2cnccc12)c1ccncc1
|
C18H17N7 331.383000 |
IJGJWWBUSDGYNE-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574364; PubChem:CID135368288
|
Local ready
Direct docking supported
|
|
E3L027794
BDB027794
|
US11458138, Example 194
CC1(Nc2nc(-c3cn[nH]c3)nc3cnccc23)CC1
|
C14H14N6 266.308000 |
FPBOXOAJFHCSCT-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574365; PubChem:CID137350506
|
Local ready
Direct docking supported
|
|
E3L027795
BDB027795
|
US11458138, Example 195
CCn1cc(-c2nc(NCC(C)C)c3ccncc3n2)cn1
|
C16H20N6 296.378000 |
PQXFKRMUBABGND-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574366; PubChem:CID137350570
|
Local ready
Direct docking supported
|
|
E3L027796
BDB027796
|
US11458138, Example 196
Cn1cc(-c2nc(NC3(C)CC3)c3ccncc3n2)cn1
|
C15H16N6 280.335000 |
SVRGRXJRAHZHME-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574367; PubChem:CID135368489
|
Local ready
Direct docking supported
|
|
E3L027797
BDB027797
|
US11458138, Example 197
CC(C)(CN)Nc1nc(-c2cn[nH]c2)nc2cnccc12
|
C14H17N7 283.339000 |
KTRVKZXQBVEQBL-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574368; PubChem:CID135368004
|
Local ready
Direct docking supported
|
|
E3L027798
BDB027798
|
US11458138, Example 198
CC1(Nc2nc(-c3ccncc3)nc3c(Cl)nccc23)CC1
|
C16H14ClN5 311.776000 |
RLWYFPYOBNIXQH-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574369; PubChem:CID135368026
|
Local ready
Direct docking supported
|
|
E3L027799
BDB027799
|
US11458138, Example 199
Cc1nccc2c(NC3(C)CC3)nc(-c3ccncc3)nc12
|
C17H17N5 291.358000 |
NCURZWASYVOQOD-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574370; PubChem:CID135368386
|
Local ready
Direct docking supported
|
|
E3L027800
BDB027800
|
US11458138, Example 251
CC(C)(C)Nc1nc(-c2ccncc2)nc2cncc(Cl)c12
|
C16H16ClN5 313.792000 |
CPJACQKXXLMUSC-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574371; PubChem:CID135368052
|
Local ready
Direct docking supported
|