| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027721
BDB027721
|
US11458138, Example 121
CC(C)(O)COCC(C)(C)Nc1nc(-c2c[nH]nc2C(F)(F)F)nc2cnccc12
|
C19H23F3N6O2 424.427000 |
DPGFQGKHNLBSLC-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574292; PubChem:CID137350488
|
Local ready
Direct docking supported
|
|
E3L027722
BDB027722
|
US11458138, Example 122
CC(C)N(C)c1nc(-c2ccncc2F)nc2cnccc12
|
C16H16FN5 297.337000 |
VBBQTFSHBKUYOD-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574293; PubChem:CID135368695
|
Local ready
Direct docking supported
|
|
E3L027723
BDB027723
|
US11458138, Example 123
CCN(c1nc(-c2ccncc2C)nc2cnccc12)C(C)C
|
C18H21N5 307.401000 |
XWSDIDHVJUXYCM-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574294; PubChem:CID135368683
|
Local ready
Direct docking supported
|
|
E3L027724
BDB027724
|
US11458138, Example 124
COCC(C)(C)Nc1nc(-c2ccncc2Cl)nc2cnccc12
|
C17H18ClN5O 343.818000 |
DICWHIMRYHKGBG-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574295; PubChem:CID135368401
|
Local ready
Direct docking supported
|
|
E3L027725
BDB027725
|
US11458138, Example 125
CC(C)(O)CC(C)(C)Nc1nc(-c2ccncc2Cl)nc2cnccc12
|
C19H22ClN5O 371.872000 |
XCYRNDNAPFRZGW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574296; PubChem:CID135368268
|
Local ready
Direct docking supported
|
|
E3L027726
BDB027726
|
US11458138, Example 126
Clc1cnccc1-c1nc(NC2CCCC2)c2ccncc2n1
|
C17H16ClN5 325.803000 |
SJESHGZXDZZGON-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574297; PubChem:CID145744581
|
Local ready
Direct docking supported
|
|
E3L027727
BDB027727
|
US11458138, Example 127
CC(C)(O)COCC(C)(C)Nc1nc(-c2ccncc2Cl)nc2cnccc12
|
C20H24ClN5O2 401.898000 |
ASGAQYCHHHOJMV-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574298; PubChem:CID135368691
|
Local ready
Direct docking supported
|
|
E3L027728
BDB027728
|
US11458138, Example 128
Cc1cnccc1-c1nc(N(C)C(C)C)c2ccncc2n1
|
C17H19N5 293.374000 |
OUMBWHSKIMMIPA-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574299; PubChem:CID135368384
|
Local ready
Direct docking supported
|
|
E3L027729
BDB027729
|
US11458138, Example 129
CC(C)(CCS(C)(=O)=O)Nc1nc(-c2ccncc2Cl)nc2cnccc12
|
C18H20ClN5O2S 405.911000 |
AFXFAZIEIXCMAR-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574300; PubChem:CID145744570
|
Local ready
Direct docking supported
|
|
E3L027730
BDB027730
|
US11458138, Example 130
CC(C)(C)Nc1nc(-c2ccncc2C(F)(F)F)nc2cnccc12
|
C17H16F3N5 347.344000 |
OSKLRIJWIBDPGW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574301; PubChem:CID135390680
|
Local ready
Direct docking supported
|
|
E3L027731
BDB027731
|
US11458138, Example 131
CC(C)(C)Nc1nc(-c2cc(Cl)ncc2C(F)(F)F)nc2cnccc12
|
C17H15ClF3N5 381.789000 |
CWHJYWBPKDUCHD-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574302; PubChem:CID135368302
|
Local ready
Direct docking supported
|
|
E3L027732
BDB027732
|
US11458138, Example 132
Clc1cnccc1-c1nc(NCCCc2nnn[nH]2)c2ccncc2n1
|
C16H14ClN9 367.804000 |
NUNIVFPHSPPLFI-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574303; PubChem:CID137350600
|
Local ready
Direct docking supported
|
|
E3L027733
BDB027733
|
BDBM574304
Cc1n[nH]cc1-c1nc(NC2(C)CC2)c2ccncc2n1
|
C15H16N6 280.335000 |
HQFDCITUHVQXEV-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574304; PubChem:CID137350911
|
Local ready
Direct docking supported
|
|
E3L027734
BDB027734
|
US11458138, Example 134
CC(C)(Nc1nc(-c2ccncc2F)nc2cnccc12)C(F)(F)F
|
C16H13F4N5 351.307000 |
LMLFNPDYWJFFPD-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574305; PubChem:CID135390652
|
Local ready
Direct docking supported
|
|
E3L027735
BDB027735
|
US11458138, Example 135
Cc1n[nH]cc1-c1nc(NC(C)(C)C(F)(F)F)c2ccncc2n1
|
C15H15F3N6 336.321000 |
CCJRVCDZHWNBTA-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574306; PubChem:CID135368049
|
Local ready
Direct docking supported
|
|
E3L027736
BDB027736
|
US11458138, Example 136
C[C@H](N(C)c1nc(-c2ccncc2F)nc2cnccc12)C(F)(F)F
|
C16H13F4N5 351.307000 |
NWTRZYRGCGNAAN-VIFPVBQESA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574307; PubChem:CID137350573
|
Local ready
Direct docking supported
|
|
E3L027737
BDB027737
|
US11458138, Example 137
C[C@@H](N(C)c1nc(-c2ccncc2F)nc2cnccc12)C(F)(F)F
|
C16H13F4N5 351.307000 |
NWTRZYRGCGNAAN-SECBINFHSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574308; PubChem:CID135368495
|
Local ready
Direct docking supported
|
|
E3L027738
BDB027738
|
US11458138, Example 138
CC1(Nc2nc(-c3ccnc(N)c3)nc3cnccc23)CC1
|
C16H16N6 292.346000 |
AJBBECKCWREWAW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574309; PubChem:CID135368440
|
Local ready
Direct docking supported
|
|
E3L027739
BDB027739
|
US11458138, Example 139
CC(C)(Nc1nc(-c2ccncc2Cl)nc2cnccc12)C(F)(F)F
|
C16H13ClF3N5 367.762000 |
GPKFECYSQTWZCI-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574310; PubChem:CID135368320
|
Local ready
Direct docking supported
|
|
E3L027740
BDB027740
|
US11458138, Example 140
Cc1n[nH]cc1-c1nc(NC(C)(C)CC(C)(C)O)c2ccncc2n1
|
C18H24N6O 340.431000 |
FDWLVSOIZUQCKU-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574311; PubChem:CID137350708
|
Local ready
Direct docking supported
|