| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L028721
BDB028721
|
US11492346, Example 131
Cc1ccc(S(=O)(=O)Nc2noc3cc(Cn4cccn4)c(C)cc23)cc1C
|
C20H20N4O3S 396.472000 |
FVKHMBIBRHTAIY-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM580786; PubChem:CID155423107
|
Local ready
Direct docking supported
|
|
E3L028722
BDB028722
|
US11492346, Example 132
COc1ccccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c(C)cc12
|
C19H18N4O4S 398.444000 |
QBIYOBZBUYEZKK-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM580787; PubChem:CID155433004
|
Local ready
Direct docking supported
|
|
E3L028723
BDB028723
|
US11492346, Example 133
COc1ccccc1S(=O)(=O)Nc1noc2cc(Cn3nccn3)cc(OC)c12
|
C18H17N5O5S 415.431000 |
SLLZJLQWFIDXEV-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM580788; PubChem:CID155433011
|
Local ready
Direct docking supported
|
|
E3L028724
BDB028724
|
BDBM581013
Cc1cc2c(=O)[nH]nc(CN)c2cc1-c1cncc(C#N)c1
|
C16H13N5O 291.314000 |
QZIQDWFIKXVZOO-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM581013; PubChem:CID177666245
|
Local ready
Direct docking supported
|
|
E3L028725
BDB028725
|
BDBM581185
CCc1cc(Cl)cc(-c2c(-c3ccc4c(=O)[nH]nc(CN)c4c3)cnn2C)c1C#N
|
C22H19ClN6O 418.888000 |
HZXRQFBPYOEHRQ-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM581185; PubChem:CID156151449
|
Local ready
Direct docking supported
|
|
E3L028726
BDB028726
|
BDBM581201
Cn1ncc(-c2ccc3c(=O)[nH]nc(CN)c3c2)c1-c1ccc(Cl)c(Cl)c1
|
C19H15Cl2N5O 400.269000 |
OYEVHGJJSDIHMF-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM581201; PubChem:CID156164760
|
Local ready
Direct docking supported
|
|
E3L028727
BDB028727
|
BDBM581318
Nc1cc(C(F)(F)F)cnc1N1CCN(CC(=O)O)CC1c1ccc(Cl)cc1
|
C18H18ClF3N4O2 414.815000 |
MUAXYQGPDYNTPA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581318; PubChem:CID166033988
|
Local ready
Direct docking supported
|
|
E3L028728
BDB028728
|
BDBM581319
CC(=O)Nc1cc(C(F)(F)F)cnc1N1CCN(CC(=O)O)CC1c1ccc(Cl)cc1
|
C20H20ClF3N4O3 456.852000 |
KLWLMSCLTIAYHT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581319; PubChem:CID166034002
|
Local ready
Direct docking supported
|
|
E3L028729
BDB028729
|
BDBM581320
Nc1cc(C(F)(F)F)ccc1N1CCN(C(=O)CC(=O)O)CC1c1ccc(Cl)cc1
|
C20H19ClF3N3O3 441.837000 |
UDVDXVRQVGMBGT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581320; PubChem:CID166033979
|
Local ready
Direct docking supported
|
|
E3L028730
BDB028730
|
BDBM581321
Cc1cc(Cl)ccc1C1CN(C(=O)CC(=O)O)CCN1c1ncc(Cl)cc1N
|
C19H20Cl2N4O3 423.300000 |
SDWKLBLPXMYQRW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581321; PubChem:CID166034009
|
Local ready
Direct docking supported
|
|
E3L028731
BDB028731
|
BDBM581322
Nc1cc(C(F)(F)F)cnc1N1CCN(C(=O)CC(=O)O)CC1c1ccc(Cl)cc1
|
C19H18ClF3N4O3 442.825000 |
CHDPTMGFWZZOMZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581322; PubChem:CID166034003
|
Local ready
Direct docking supported
|
|
E3L028732
BDB028732
|
BDBM581323
CC1CN(c2ncc(Cl)cc2N)C(c2ccc(Cl)cc2)CN1C(=O)CC(=O)O
|
C19H20Cl2N4O3 423.300000 |
JYUNRNBZECUCAS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581323; PubChem:CID166034012
|
Local ready
Direct docking supported
|
|
E3L028733
BDB028733
|
BDBM581324
Nc1cc(Cl)ccc1N1CCN(C(=O)CC(=O)O)CC1c1ccc(Cl)cc1
|
C19H19Cl2N3O3 408.285000 |
YQXDPYHVQPTHNN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581324; PubChem:CID166034025
|
Local ready
Direct docking supported
|
|
E3L028734
BDB028734
|
BDBM581325
CC(C)C1CN(c2ncc(Cl)cc2N)C(c2ccc(Cl)cc2)CN1C(=O)CC(=O)O
|
C21H24Cl2N4O3 451.354000 |
WUIWLLCOWSWKRX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581325; PubChem:CID166033975
|
Local ready
Direct docking supported
|
|
E3L028735
BDB028735
|
BDBM581326
Nc1cc(Cl)cnc1N1CCN(C(=O)CN2CCNCC2)CC1c1ccc(Cl)cc1
|
C21H26Cl2N6O 449.386000 |
WMPQOIIXJHZMQF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581326; PubChem:CID166034035
|
Local ready
Direct docking supported
|
|
E3L028736
BDB028736
|
BDBM581327
Nc1cc(Cl)cnc1N1CCN(C(=O)CCC(=O)O)CC1c1ccc(Cl)cc1
|
C19H20Cl2N4O3 423.300000 |
PULXJTSGDJALOH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581327; PubChem:CID166033983
|
Local ready
Direct docking supported
|
|
E3L028737
BDB028737
|
BDBM581328
Nc1cc(Cl)cnc1N1CCN(C(=O)NCC(=O)O)CC1c1ccc(Cl)cc1
|
C18H19Cl2N5O3 424.288000 |
RHNLDRLYYXFJEO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581328; PubChem:CID166033982
|
Local ready
Direct docking supported
|
|
E3L028738
BDB028738
|
BDBM581329
Nc1cc(Cl)cnc1N1CCN(C(=O)C2CNCCN2)CC1c1ccc(Cl)cc1
|
C20H24Cl2N6O 435.359000 |
SZLHHILGNRJTSA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581329; PubChem:CID166034023
|
Local ready
Direct docking supported
|
|
E3L028739
BDB028739
|
BDBM581330
Nc1cc(Cl)cnc1N1CCN(C(=O)c2cnccc2C(=O)O)CC1c1ccc(Cl)cc1
|
C22H19Cl2N5O3 472.332000 |
YFAYIGHPKVZSAG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581330; PubChem:CID166033980
|
Local ready
Direct docking supported
|
|
E3L028740
BDB028740
|
BDBM581331
CC(C)CC1CN(c2ncc(Cl)cc2N)C(c2ccc(Cl)cc2)CN1C(=O)CC(=O)O
|
C22H26Cl2N4O3 465.381000 |
MNLKGSKHSRDVMZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581331; PubChem:CID166033985
|
Local ready
Direct docking supported
|