| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L028741
BDB028741
|
BDBM581332
C[C@H]1CN(C(=O)CC(=O)O)C[C@@H](c2ccc(Cl)cc2)N1c1ccc(Cl)cc1
|
C20H20Cl2N2O3 407.297000 |
LFURLFAGZIGVDM-UGSOOPFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581332; PubChem:CID166034006
|
Local ready
Direct docking supported
|
|
E3L028742
BDB028742
|
BDBM581333
CC[C@H]1CN(C(=O)CC(=O)O)C[C@@H](c2ccc(Cl)cc2)N1c1ccc(Cl)cc1
|
C21H22Cl2N2O3 421.324000 |
AMCCEPUUHAKALM-HKUYNNGSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581333; PubChem:CID166033996
|
Local ready
Direct docking supported
|
|
E3L028743
BDB028743
|
BDBM581334
Nc1cc(Cl)cnc1N1CCN(C(=O)CCCC(=O)O)CC1c1ccc(Cl)cc1
|
C20H22Cl2N4O3 437.327000 |
PMOMIYXCXVUGOK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581334; PubChem:CID166034011
|
Local ready
Direct docking supported
|
|
E3L028744
BDB028744
|
BDBM581335
Nc1cc(Cl)cnc1N1CCN(C(=O)C2CC2C(=O)O)CC1c1ccc(Cl)cc1
|
C20H20Cl2N4O3 435.311000 |
UJEBKBZZUZSGCC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581335; PubChem:CID166033977
|
Local ready
Direct docking supported
|
|
E3L028745
BDB028745
|
BDBM581336
Nc1cc(Cl)cnc1N1CCN(C(=O)[C@H]2CCC2C(=O)O)CC1c1ccc(Cl)cc1
|
C21H22Cl2N4O3 449.338000 |
GHYBOOXQXXQZDG-HJOIGYKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581336; PubChem:CID166033999
|
Local ready
Direct docking supported
|
|
E3L028746
BDB028746
|
BDBM581337
O=C(O)CC(=O)N1C[C@H](C2CC2)N(c2ccc(Cl)cc2)[C@H](c2ccc(Cl)cc2)C1
|
C22H22Cl2N2O3 433.335000 |
SMEWYFLMSPPPJX-UXHICEINSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581337; PubChem:CID166034020
|
Local ready
Direct docking supported
|
|
E3L028747
BDB028747
|
BDBM581338
CC(C)C[C@H]1CN(C(=O)CC(=O)O)C[C@@H](c2ccc(Cl)cc2)N1c1ccc(Cl)cc1
|
C23H26Cl2N2O3 449.378000 |
IJZISDKGLIDRSW-SFTDATJTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581338; PubChem:CID166034030
|
Local ready
Direct docking supported
|
|
E3L028748
BDB028748
|
BDBM581339
CNC(=O)CC(=O)N1CCN(c2ncc(Cl)cc2N)C(c2ccc(Cl)cc2)C1
|
C19H21Cl2N5O2 422.316000 |
NGQNMBLUHSMDJX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581339; PubChem:CID166033997
|
Local ready
Direct docking supported
|
|
E3L028749
BDB028749
|
BDBM581340
CNC(=O)CN1CCN(c2ncc(Cl)cc2N)C(c2ccc(Cl)cc2)C1
|
C18H21Cl2N5O 394.306000 |
GFPKWYSYUAPANW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581340; PubChem:CID166033990
|
Local ready
Direct docking supported
|
|
E3L028750
BDB028750
|
BDBM581342
Nc1cc(Cl)cnc1N1CCN(C(=O)C2CC[C@@H]2C(=O)O)CC1c1ccc(Cl)cc1
|
C21H22Cl2N4O3 449.338000 |
GHYBOOXQXXQZDG-PQUAAJSLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581342; PubChem:CID166033991
|
Local ready
Direct docking supported
|
|
E3L028751
BDB028751
|
BDBM581343
Nc1cc(Cl)cnc1N1CCN(C(=O)C2CC(C(=O)O)C2)CC1c1ccc(Cl)cc1
|
C21H22Cl2N4O3 449.338000 |
OXWJIMQTDMBOQA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581343; PubChem:CID166034010
|
Local ready
Direct docking supported
|
|
E3L028752
BDB028752
|
BDBM581344
Nc1cc(Cl)cnc1N1CCN(C(=O)c2cccc(C(=O)O)c2)CC1c1ccc(Cl)cc1
|
C23H20Cl2N4O3 471.344000 |
WLEYMPYMLVHPEV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581344; PubChem:CID166034004
|
Local ready
Direct docking supported
|
|
E3L028753
BDB028753
|
BDBM581345
Nc1cc(Cl)cnc1N1CCN(C(=O)c2ccc(C(=O)O)cc2)CC1c1ccc(Cl)cc1
|
C23H20Cl2N4O3 471.344000 |
WDYAZYSPOFTKSZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581345; PubChem:CID166034036
|
Local ready
Direct docking supported
|
|
E3L028754
BDB028754
|
BDBM581346
CC(C)C[C@H]1CN(C(=O)CC(=O)O)CC(c2ccc(Cl)cc2)N1c1ncc(Cl)cc1N
|
C22H26Cl2N4O3 465.381000 |
BCURZNRLBFGNAN-KKFHFHRHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581346; PubChem:CID166034019
|
Local ready
Direct docking supported
|
|
E3L028755
BDB028755
|
BDBM581347
CC(C)(C)C[C@H]1CN(C(=O)CC(=O)O)C[C@@H](c2ccc(Cl)cc2)N1c1ncc(Cl)cc1N
|
C23H28Cl2N4O3 479.408000 |
DHNNFPMNWVKVKV-HKUYNNGSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581347; PubChem:CID166034014
|
Local ready
Direct docking supported
|
|
E3L028756
BDB028756
|
BDBM581348
Nc1cc(Cl)cnc1N1[C@@H](CC2CCCC2)CN(C(=O)CC(=O)O)C[C@H]1c1ccc(Cl)cc1
|
C24H28Cl2N4O3 491.419000 |
QPJGRJUFWMMHTA-FPOVZHCZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM581348; PubChem:CID166034039
|
Local ready
Direct docking supported
|
|
E3L028757
BDB028757
|
3-(Phenylsulfanyl)piperidine-2,6-dione
O=C1CCC(Sc2ccccc2)C(=O)N1
|
C11H11NO2S 221.281000 |
DVTWEZHTLIJLKO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581717; PubChem:CID142623399
|
Local ready
Direct docking supported
|
|
E3L028758
BDB028758
|
3-Pyridin-2-ylsulfanylpiperidine-2,6-dione
O=C1CCC(Sc2ccccn2)C(=O)N1
|
C10H10N2O2S 222.269000 |
KVBUVBCMLQYSKI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581718; PubChem:CID142623451
|
Local ready
Direct docking supported
|
|
E3L028759
BDB028759
|
3-(4-Fluorophenyl)sulfanylpiperidine-2,6-dione
O=C1CCC(Sc2ccc(F)cc2)C(=O)N1
|
C11H10FNO2S 239.271000 |
QWDSHHPDHGILCA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581719; PubChem:CID91648396
|
Local ready
Direct docking supported
|
|
E3L028760
BDB028760
|
BDBM581720
O=C1CCC(Sc2nc3ccc(Cl)cc3[nH]2)C(=O)N1
|
C12H10ClN3O2S 295.751000 |
QIBXNDFNYXFSIA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM581720; PubChem:CID86793742
|
Local ready
Direct docking supported
|