| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L029281
BDB029281
|
US11524962, Example 52
Cc1ncnc2c1ccn2[C@@H]1O[C@H]([C@H](O)c2nc3c(s2)CCC3)[C@@H](O)[C@H]1O
|
C18H20N4O4S 388.449000 |
LGXJELYWRWBUQZ-SFUJAXRZSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM584248; PubChem:CID162505642
|
Local ready
Direct docking supported
|
|
E3L029282
BDB029282
|
US11524962, Example 53
OCCc1ncnc2c1ccn2[C@@H]1O[C@H]([C@H](O)c2ccc3c(c2)CC3)[C@@H](O)[C@H]1O
|
C21H23N3O5 397.431000 |
PQELDOIJDUZCHE-TWHPPBISSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM584249; PubChem:CID162505677
|
Local ready
Direct docking supported
|
|
E3L029283
BDB029283
|
US11524962, Example 54
CNc1ncnc2c1ccn2[C@@H]1O[C@H]([C@H](O)c2ccc3c(c2)CC3)[C@@H](O)[C@H]1O
|
C20H22N4O4 382.420000 |
OVZNAPQBSKTSCY-QRXRQMIZSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM584250; PubChem:CID162505629
|
Local ready
Direct docking supported
|
|
E3L029284
BDB029284
|
US11524962, Example 55
O[C@@H]1[C@H](O)[C@@H]([C@H](O)c2ccc3c(c2)CC3)O[C@H]1n1ccc2c(CCOCc3ccccc3)ncnc21
|
C28H29N3O5 487.556000 |
YZAQLOLHYLSUEL-TUDBGTMHSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM584251; PubChem:CID162505636
|
Local ready
Direct docking supported
|
|
E3L029285
BDB029285
|
US11524962, Example 56
O[C@@H]1[C@H](O)[C@@H]([C@H](O)c2ccc3c(c2)CC3)O[C@H]1n1ccc2c(Cl)ncnc21
|
C19H18ClN3O4 387.823000 |
PZGSQKASGVWEDK-PPLBCVRQSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM584252; PubChem:CID162505658
|
Local ready
Direct docking supported
|
|
E3L029286
BDB029286
|
BDBM585773
Cc1cc(C(=O)Nc2cccc([C@]3(Cc4nncn4C)C[C@@H](C#N)C3)c2)nc(C2CC2)n1
|
C24H25N7O 427.512000 |
AVHROJXYFUWPQG-BCTVQRCUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585773
|
Local ready
Direct docking supported
|
|
E3L029287
BDB029287
|
BDBM585786
Cc1cc(C(=O)Nc2cccc([C@]3(Cc4nncn4C)C[C@H](C#N)C3)c2)nc(C2CC2)n1
|
C24H25N7O 427.512000 |
AVHROJXYFUWPQG-ONEIWYMKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585786
|
Local ready
Direct docking supported
|
|
E3L029288
BDB029288
|
BDBM585788
Cn1cnnc1C[C@]1(c2cccc(N3Cc4c(cccc4C(F)(F)F)C3=O)c2)C[C@H](C#N)C1
|
C24H20F3N5O 451.452000 |
IRYIWQSUGCWZFS-CWSKOGRWSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585788
|
Local ready
Direct docking supported
|
|
E3L029289
BDB029289
|
BDBM585789
Cn1cnnc1C[C@]1(c2cccc(N3Cc4c(cc(CN5CCC6(CC6)C5)cc4C(F)(F)F)C3=O)c2)C[C@H](C#N)C1
|
C31H31F3N6O 560.624000 |
BRRXAIQELJKDCC-RYECUYIGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585789
|
Local ready
Direct docking supported
|
|
E3L029290
BDB029290
|
BDBM585790
CCC1CN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(Cc5nncn5C)C[C@@H](C#N)C4)c2)C3=O)CCCO1
|
C32H35F3N6O2 592.666000 |
ZTYPHHAXRXVFCW-CZMMVBKASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585790
|
Local ready
Direct docking supported
|
|
E3L029291
BDB029291
|
BDBM585791
C[C@@H]1CN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(Cc5nncn5C)C[C@@H](C#N)C4)c2)C3=O)CCO1
|
C30H31F3N6O2 564.612000 |
TYPNQYBPYKTZQL-DOJXGVHPSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585791
|
Local ready
Direct docking supported
|
|
E3L029292
BDB029292
|
BDBM585792
C[C@@H]1CN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(Cc5nncn5C)C[C@@](C)(C#N)C4)c2)C3=O)CCO1
|
C31H33F3N6O2 578.639000 |
VIYUQXRPBWMFRZ-FQOCFFJISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585792
|
Local ready
Direct docking supported
|
|
E3L029293
BDB029293
|
BDBM585793
Cc1cc(C(=O)Nc2cccc([C@]3(Cc4nncn4C)C[C@@](C)(C#N)C3)c2)nc(C2CC2)n1
|
C25H27N7O 441.539000 |
WMCOEMPWXJRFMB-SOAUALDESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585793
|
Local ready
Direct docking supported
|
|
E3L029294
BDB029294
|
BDBM585794
Cc1cc(C(=O)Nc2cccc([C@]3(Cc4nncn4C)C[C@](C)(C#N)C3)c2)nc(C2CC2)n1
|
C25H27N7O 441.539000 |
WMCOEMPWXJRFMB-PLQXJYEYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585794
|
Local ready
Direct docking supported
|
|
E3L029295
BDB029295
|
BDBM585795
C[C@@H]1CN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(Cc5nncn5C)C[C@](C)(C#N)C4)c2)C3=O)CCO1
|
C31H33F3N6O2 578.639000 |
VIYUQXRPBWMFRZ-HJHQTFHHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585795
|
Local ready
Direct docking supported
|
|
E3L029296
BDB029296
|
BDBM585796
C[C@@H]1CN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(Cc5nncn5C)C[C@@H](C#N)C4)c2)C3=O)CCC1(F)F
|
C31H31F5N6O 598.620000 |
CHJJASJWFRCRQD-DOJXGVHPSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585796
|
Local ready
Direct docking supported
|
|
E3L029297
BDB029297
|
BDBM585797
Cn1cnnc1C[C@]1(c2cccc(N3Cc4c(cc(CNC5CC6C(C5)C6(F)F)cc4C(F)(F)F)C3=O)c2)C[C@H](C#N)C1
|
C31H29F5N6O 596.604000 |
IHKKIDILCUXTDQ-UQLKZTIISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585797
|
Local ready
Direct docking supported
|
|
E3L029298
BDB029298
|
BDBM585798
CC1CCCN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(Cc5nncn5C)C[C@@H](C#N)C4)c2)C3=O)CC1
|
C32H35F3N6O 576.667000 |
WRWBXQMNSPBQNV-AVCJDWODSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585798
|
Local ready
Direct docking supported
|
|
E3L029299
BDB029299
|
BDBM585799
Cn1cnnc1C[C@]1(c2cccc(N3Cc4c(cc(CN5CCC[C@H](C(F)(F)F)C5)cc4C(F)(F)F)C3=O)c2)C[C@H](C#N)C1
|
C31H30F6N6O 616.610000 |
YGLPIRUNHRZFLN-GOGYHYQUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585799
|
Local ready
Direct docking supported
|
|
E3L029300
BDB029300
|
BDBM585800
C[C@@H]1CN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cccc([C@]4(Cc5nncn5C)C[C@@H](C#N)C4)c2)C3=O)C[C@H](C)O1
|
C31H33F3N6O2 578.639000 |
JYAMUOCSQXLCDG-YOPDCPDTSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM585800
|
Local ready
Direct docking supported
|