| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L032121
BDB032121
|
BDBM649902
C=CC(=O)N1CCC[C@@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4ccn[nH]4)n3)nc2)C1
|
C23H23N7O3 445.483000 |
IAQIZJLJAOFQPG-OAHLLOKOSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649902; PubChem:CID170687588
|
Local ready
Direct docking supported
|
|
E3L032122
BDB032122
|
BDBM649903
C=CC(=O)N1CCC[C@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4cnoc4)n3)nc2)C1
|
C23H22N6O4 446.467000 |
RWFRXULGLWODPB-HNNXBMFYSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649903; PubChem:CID156867602
|
Local ready
Direct docking supported
|
|
E3L032123
BDB032123
|
BDBM649904
C=CC(=O)N1CCC[C@@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4cnoc4)n3)nc2)C1
|
C23H22N6O4 446.467000 |
RWFRXULGLWODPB-OAHLLOKOSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649904; PubChem:CID156867575
|
Local ready
Direct docking supported
|
|
E3L032124
BDB032124
|
BDBM649905
C=CC(=O)N1CCC[C@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4ccn[nH]4)n3)cc2F)C1
|
C24H23FN6O3 462.485000 |
WBOSXDINKGLASP-HNNXBMFYSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649905; PubChem:CID166761169
|
Local ready
Direct docking supported
|
|
E3L032125
BDB032125
|
BDBM649906
C=CC(=O)N1CCC[C@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4cnoc4)n3)cc2F)C1
|
C24H22FN5O4 463.469000 |
XOEYQRKCJFQPPX-HNNXBMFYSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649906; PubChem:CID156867603
|
Local ready
Direct docking supported
|
|
E3L032126
BDB032126
|
BDBM649907
C=CC(=O)N1CCC[C@@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4ccn[nH]4)n3)cc2F)C1
|
C24H23FN6O3 462.485000 |
WBOSXDINKGLASP-OAHLLOKOSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649907; PubChem:CID156867588
|
Local ready
Direct docking supported
|
|
E3L032127
BDB032127
|
BDBM649908
C=CC(=O)N1CCC[C@@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4cnoc4)n3)cc2F)C1
|
C24H22FN5O4 463.469000 |
XOEYQRKCJFQPPX-OAHLLOKOSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649908; PubChem:CID170687589
|
Local ready
Direct docking supported
|
|
E3L032128
BDB032128
|
BDBM649909
C=CC(=O)N[C@H]1C[C@@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4ccn[nH]4)n3)nc2)CN(CC(F)(F)F)C1
|
C25H25F3N8O3 542.522000 |
FRILDNAKNYIUEV-WBVHZDCISA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649909; PubChem:CID156867579
|
Local ready
Direct docking supported
|
|
E3L032129
BDB032129
|
BDBM649910
C=CC(=O)N[C@H]1C[C@@H](C(=O)Nc2ccc(NC(=O)c3cccc(-c4ccn[nH]4)n3)nc2)CN(CC(F)F)C1
|
C25H26F2N8O3 524.532000 |
MPIAHORCLNECOJ-WBVHZDCISA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM649910; PubChem:CID156867583
|
Local ready
Direct docking supported
|
|
E3L032130
BDB032130
|
BDBM651595
Cc1ccc(NC(=O)OCc2cc(Br)c3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1Cl
|
C22H19BrClN3O5 520.767000 |
HIUIQLZWQFSNJU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651595; PubChem:CID166074269
|
Local ready
Direct docking supported
|
|
E3L032131
BDB032131
|
BDBM651596
Cc1ccc(NC(=O)OCc2cc(C#N)c3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1Cl
|
C23H19ClN4O5 466.881000 |
QZELYYTUBCOLMU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651596; PubChem:CID166074256
|
Local ready
Direct docking supported
|
|
E3L032132
BDB032132
|
BDBM651597
Cc1ccc(NC(=O)OCc2cc(F)c3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1Cl
|
C22H19ClFN3O5 459.861000 |
KMNZMLMTRCKADU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651597; PubChem:CID166074270
|
Local ready
Direct docking supported
|
|
E3L032133
BDB032133
|
BDBM651598
Cc1ccc(NC(=O)OCc2cc(Cl)c3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1Cl
|
C22H19Cl2N3O5 476.316000 |
NLZDCOXIRKSMLI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651598; PubChem:CID166074329
|
Local ready
Direct docking supported
|
|
E3L032134
BDB032134
|
BDBM651599
COc1cc(COC(=O)Nc2ccc(C)c(Cl)c2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C23H22ClN3O6 471.897000 |
ZGXWQMSLKHWYCF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651599; PubChem:CID166074283
|
Local ready
Direct docking supported
|
|
E3L032135
BDB032135
|
BDBM651600
O=C1CCC(N2Cc3c(F)cc(COC(=O)Nc4cc(F)cc(OC(F)F)c4)cc3C2=O)C(=O)N1
|
C22H17F4N3O6 495.385000 |
CAYYBHUMYFSJGX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651600; PubChem:CID166074248
|
Local ready
Direct docking supported
|
|
E3L032136
BDB032136
|
BDBM651601
O=C1CCC(N2Cc3c(F)cc(COC(=O)Nc4ccc(F)c(OC(F)F)c4)cc3C2=O)C(=O)N1
|
C22H17F4N3O6 495.385000 |
SJZDDYYCNBHQQZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651601; PubChem:CID166074356
|
Local ready
Direct docking supported
|
|
E3L032137
BDB032137
|
BDBM651602
O=C1CCC(N2Cc3c(F)cc(COC(=O)Nc4ccc(-c5ccccc5)nc4)cc3C2=O)C(=O)N1
|
C26H21FN4O5 488.475000 |
BZNHBORWVRFLBK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651602; PubChem:CID166074281
|
Local ready
Direct docking supported
|
|
E3L032138
BDB032138
|
BDBM651603
CC(C)(C)c1ccc(NC(=O)OCc2cc(F)c3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cn1
|
C24H25FN4O5 468.485000 |
UHZFEFIMOTUMFD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651603; PubChem:CID166074251
|
Local ready
Direct docking supported
|
|
E3L032139
BDB032139
|
BDBM651604
CC(C)(C)c1ccc(NC(=O)OCc2cc(F)c3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1
|
C25H26FN3O5 467.497000 |
FWPMTNINXWCSHR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651604; PubChem:CID166074319
|
Local ready
Direct docking supported
|
|
E3L032140
BDB032140
|
BDBM651605
O=C1CCC(N2Cc3c(F)cc(COC(=O)Nc4ccc(-c5ccccn5)cc4)cc3C2=O)C(=O)N1
|
C26H21FN4O5 488.475000 |
MKALCODESUTFED-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651605; PubChem:CID166074228
|
Local ready
Direct docking supported
|