| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L032181
BDB032181
|
BDBM651646
COc1cc(COC(=O)Nc2cc(C)cc(C)c2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C24H25N3O6 451.479000 |
RBAWCNPLPHOYPY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651646; PubChem:CID166074352
|
Local ready
Direct docking supported
|
|
E3L032182
BDB032182
|
BDBM651647
COc1cc(COC(=O)Nc2cccc(OC(F)F)c2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C23H21F2N3O7 489.431000 |
FXRUTIHTTXLFRK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651647; PubChem:CID166074302
|
Local ready
Direct docking supported
|
|
E3L032183
BDB032183
|
BDBM651648
COc1cc(COC(=O)Nc2cccc(C(C)(C)C)c2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C26H29N3O6 479.533000 |
XOJODOCRJGRDAC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651648; PubChem:CID166074367
|
Local ready
Direct docking supported
|
|
E3L032184
BDB032184
|
BDBM651649
COc1cc(COC(=O)Nc2cccc(OC(F)(F)F)c2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C23H20F3N3O7 507.421000 |
KDNWEQBYQFPISU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651649; PubChem:CID166074278
|
Local ready
Direct docking supported
|
|
E3L032185
BDB032185
|
BDBM651650
COc1cc(COC(=O)Nc2cc(-c3ccccc3)ccn2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C27H24N4O6 500.511000 |
ULLUFJRJPFHEGA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651650; PubChem:CID166074242
|
Local ready
Direct docking supported
|
|
E3L032186
BDB032186
|
BDBM651651
COc1cc(COC(=O)Nc2ccc(C3CCC3)cc2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C26H27N3O6 477.517000 |
AOKLKMXIDQFSLL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651651; PubChem:CID166074243
|
Local ready
Direct docking supported
|
|
E3L032187
BDB032187
|
BDBM651652
COc1cc(COC(=O)Nc2cccc(OC3CC3)c2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C25H25N3O7 479.489000 |
LUJIEROYLWZKTP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651652; PubChem:CID166074321
|
Local ready
Direct docking supported
|
|
E3L032188
BDB032188
|
BDBM651653
COc1cc(COC(=O)Nc2cnc(-c3ccccc3)c(C)c2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C28H26N4O6 514.538000 |
CJPOCWXKYPARLC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651653; PubChem:CID166074291
|
Local ready
Direct docking supported
|
|
E3L032189
BDB032189
|
BDBM651654
COc1cc(COC(=O)Nc2ccc(-c3ccccc3C)nc2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C28H26N4O6 514.538000 |
MBJYVPHDPODQIH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651654; PubChem:CID166074348
|
Local ready
Direct docking supported
|
|
E3L032190
BDB032190
|
BDBM651655
O=C1CCC(N2Cc3c(F)cc(COC(=O)Nc4cc(F)c(F)c(Cl)c4)cc3C2=O)C(=O)N1
|
C21H15ClF3N3O5 481.814000 |
KLLAQCKOLPBHIR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651655; PubChem:CID166074292
|
Local ready
Direct docking supported
|
|
E3L032191
BDB032191
|
BDBM651656
COc1cc(COC(=O)Nc2ccc(N3CCC[C@@H]3C)nc2)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C26H29N5O6 507.547000 |
RJUGFQATUXQXSB-OOJLDXBWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651656; PubChem:CID166074272
|
Local ready
Direct docking supported
|
|
E3L032192
BDB032192
|
BDBM651657
COc1c(COC(=O)Nc2ccc(C)c(Cl)c2)ccc2c1C(=O)N(C1CCC(=O)NC1=O)C2
|
C23H22ClN3O6 471.897000 |
ZGFHPHUKNIQMOJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651657; PubChem:CID166074305
|
Local ready
Direct docking supported
|
|
E3L032193
BDB032193
|
BDBM651658
Cc1ccc(NC(=O)OCc2ccc3c(c2F)C(=O)N(C2CCC(=O)NC2=O)C3)cc1Cl
|
C22H19ClFN3O5 459.861000 |
YHAOJUVJIQSFRU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651658; PubChem:CID166074296
|
Local ready
Direct docking supported
|
|
E3L032194
BDB032194
|
BDBM651659
Cc1ccc(NC(=O)OCc2ccc3c(c2Cl)C(=O)N(C2CCC(=O)NC2=O)C3)cc1Cl
|
C22H19Cl2N3O5 476.316000 |
AMCKRIRQIBKIDA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651659; PubChem:CID166074322
|
Local ready
Direct docking supported
|
|
E3L032195
BDB032195
|
BDBM651660
Cc1ccc(NC(=O)OCc2ccc3c(c2C)C(=O)N(C2CCC(=O)NC2=O)C3)cc1Cl
|
C23H22ClN3O5 455.898000 |
YWEPIHYNBGHYGJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM651660; PubChem:CID166074324
|
Local ready
Direct docking supported
|
|
E3L032196
BDB032196
|
US20240059691, Example 1001
CN1CCC(Oc2ccc(CNc3ccc4c(N)nccc4c3)cn2)CC1
|
C21H25N5O 363.465000 |
GXJGGSLRORREAO-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM652421; PubChem:CID170928349
|
Local ready
Direct docking supported
|
|
E3L032197
BDB032197
|
BDBM652422
CN1CCC(Oc2ccc(CNc3cccc4c(N)nccc34)cc2)CC1
|
C22H26N4O 362.477000 |
UMFFCYDWHBQNPV-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM652422; PubChem:CID170928480
|
Local ready
Direct docking supported
|
|
E3L032198
BDB032198
|
BDBM652423
CN1CCC(Oc2ccc(CNc3ccc4ccnc(N)c4c3)cc2)CC1
|
C22H26N4O 362.477000 |
NKLMFKCXUKBJOU-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM652423; PubChem:CID163390390
|
Local ready
Direct docking supported
|
|
E3L032199
BDB032199
|
US20240059691, Example 1004
CN1CCC(Oc2ccc(CNc3cnc4[nH]cc(Cl)c4c3)cc2)CC1
|
C20H23ClN4O 370.884000 |
ITXMGHQYSZOAPX-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM652424; PubChem:CID163390384
|
Local ready
Direct docking supported
|
|
E3L032200
BDB032200
|
US20240059691, Example 1005
CN1CCC(COc2ccc(CNc3ccc4c(N)nccc4c3)cn2)CC1
|
C22H27N5O 377.492000 |
UXQJFMQHQIXERQ-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM652425; PubChem:CID163390445
|
Local ready
Direct docking supported
|