| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L033541
BDB033541
|
US12172992, Example 18
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cc3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C43H50N10O4 770.939000 |
BGEYTGUDGVSOEH-URLMMPGGSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662964; PubChem:CID171663797
|
Local ready
Direct docking supported
|
|
E3L033542
BDB033542
|
US12172992, Example 19
Cc1cc(-c2cc(Nc3ccc(CCN4CCN(c5ccc(N6CCC(=O)NC6=O)cc5)CC4)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C41H47N11O4 757.900000 |
CMSGLJCUFFEKTP-HHHXNRCGSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM662965; PubChem:CID169205513
|
Local ready
Direct docking supported
|
|
E3L033543
BDB033543
|
BDBM662966
Cc1noc(C)c1-c1ccc2c(c1)nc([C@H]1CCCC(=O)N1c1ccc(F)c(F)c1)n2C1CC2C(C1)C2(F)F
|
C29H26F4N4O2 538.545000 |
OISTZKLYQBJTIE-OFZJYCOJSA-N | Q09472, Q92793 | Histone acetyltransferase p300, CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM662966; PubChem:CID171414140
|
Local ready
Direct docking supported
|
|
E3L033544
BDB033544
|
BDBM662967
COC1CCC(n2c([C@@H]3C[C@H]4C[C@H]4C(=O)N3c3ccc(F)c(F)c3)nc3cc(-c4c(C)noc4C)ccc32)CC1
|
C31H32F2N4O3 546.618000 |
HPCJDXNTSDAQDE-DSJRWBPRSA-N | Q09472, Q92793 | Histone acetyltransferase p300, CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM662967; PubChem:CID171414188
|
Local ready
Direct docking supported
|
|
E3L033545
BDB033545
|
BDBM662968
COC1CCC(n2c([C@H]3C[C@@H]4C[C@@H]4C(=O)N3c3ccc(F)c(F)c3)nc3cc(-c4c(C)noc4C)ccc32)CC1
|
C31H32F2N4O3 546.618000 |
HPCJDXNTSDAQDE-UCCSQLMKSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM662968; PubChem:CID171414197
|
Local ready
Direct docking supported
|
|
E3L033546
BDB033546
|
BDBM662969
COC1CCC(n2c([C@@H]3CN(C)C(=O)N3c3ccc(F)c(F)c3)nc3cc(-c4c(C)noc4C)ccc32)CC1
|
C29H31F2N5O3 535.595000 |
YMVDJIIWWCHTGJ-WGJJQBRPSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM662969; PubChem:CID171414189
|
Local ready
Direct docking supported
|
|
E3L033547
BDB033547
|
BDBM662970
Cc1noc(C)c1-c1ccc2c(c1)nc([C@H]1CCCC(=O)N1c1ccc(F)c(F)c1)n2C1CCC2(CC1)COC2
|
C31H32F2N4O3 546.618000 |
QSVIWFPLAMBFTJ-HHHXNRCGSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM662970; PubChem:CID171414179
|
Local ready
Direct docking supported
|
|
E3L033548
BDB033548
|
BDBM662971
COC12CCC(n3c([C@H]4CCCC(=O)N4c4ccc(F)c(F)c4)nc4cc(-c5c(C)noc5C)ccc43)(CC1)CC2
|
C32H34F2N4O3 560.645000 |
DGOLCOFYVOLBRF-XJRVHGQPSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM662971; PubChem:CID171414209
|
Local ready
Direct docking supported
|
|
E3L033549
BDB033549
|
BDBM662972
COC1CCC(n2c([C@H]3C[C@@H]4C[C@@H]4C(=O)N3c3ccc(F)c(F)c3)nc3c(C)c(-c4c(C)noc4C)ccc32)CC1
|
C32H34F2N4O3 560.645000 |
ZKADBCSTXDNSSW-AIZLXCEBSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM662972; PubChem:CID171414130
|
Local ready
Direct docking supported
|
|
E3L033550
BDB033550
|
BDBM662973
COC1CCC(n2c([C@H]3CCSC(=O)N3c3ccc(F)c(F)c3)nc3cc(-c4c(C)noc4C)ccc32)CC1
|
C29H30F2N4O3S 552.647000 |
LLPJIAZKCYSPBI-YBFPRZSNSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM662973; PubChem:CID171414142
|
Local ready
Direct docking supported
|
|
E3L033551
BDB033551
|
BDBM662974
COC12CCC(n3c([C@@H]4C[C@@H]5C[C@@H]5C(=O)N4c4ccc(F)c(F)c4)nc4cc(-c5c(C)noc5C)ccc43)(CC1)CC2
|
C33H34F2N4O3 572.656000 |
MSDYJZMQGKWYMG-FVZWOYGGSA-N | Q09472, Q92793 | Histone acetyltransferase p300, CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM662974; PubChem:CID171414168
|
Local ready
Direct docking supported
|
|
E3L033552
BDB033552
|
BDBM662975
COC12CCC(n3c([C@H]4CCOC(=O)N4c4ccc(F)c(F)c4)nc4cc(-c5c(C)noc5C)ccc43)(CC1)CC2
|
C31H32F2N4O4 562.617000 |
YOOXMAYMGCHPNB-GXUJUKEASA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM662975; PubChem:CID171414158
|
Local ready
Direct docking supported
|
|
E3L033553
BDB033553
|
BDBM662976
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cnc12
|
C18H17N5O5S 415.431000 |
KLQFEAGLHOIXGE-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM662976; PubChem:CID169859981
|
Local ready
Direct docking supported
|
|
E3L033554
BDB033554
|
BDBM662977
COc1ccnc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12
|
C19H19N5O6S 445.457000 |
PYZGQUVQUOVACR-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM662977; PubChem:CID169859982
|
Local ready
Direct docking supported
|
|
E3L033555
BDB033555
|
BDBM662978
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC(F)F)c12
|
C20H18F2N4O6S 480.449000 |
BEHGOPLAXVUELM-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM662978; PubChem:CID171417579
|
Local ready
Direct docking supported
|
|
E3L033556
BDB033556
|
BDBM662979
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OCC(F)(F)F)c12
|
C21H19F3N4O6S 512.466000 |
PAMWUDQMIBTCBB-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM662979; PubChem:CID169859983
|
Local ready
Direct docking supported
|
|
E3L033557
BDB033557
|
BDBM662980
COc1ccnc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC(F)F)c12
|
C19H17F2N5O6S 481.437000 |
GDZFRDPZFFOMKK-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM662980; PubChem:CID171417544
|
Local ready
Direct docking supported
|
|
E3L033558
BDB033558
|
BDBM662981
COc1ccccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC(F)F)c12
|
C19H16F2N4O5S 450.423000 |
MOVVTQKJIFRELQ-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM662981; PubChem:CID171417497
|
Local ready
Direct docking supported
|
|
E3L033559
BDB033559
|
BDBM662982
O=S(=O)(Nc1noc2cc(Cn3cccn3)cc(OC(F)F)c12)c1ccccc1OC(F)(F)F
|
C19H13F5N4O5S 504.393000 |
YFTLMRWQCPYQRE-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM662982; PubChem:CID171417591
|
Local ready
Direct docking supported
|
|
E3L033560
BDB033560
|
BDBM662983
COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC(F)(F)F)c12
|
C20H17F3N4O6S 498.439000 |
QRWXQULMXWGKIH-UHFFFAOYSA-N | Q92794 | Histone acetyltransferase KAT6A |
BindingDB, PubChem
BindingDB:BDBM662983; PubChem:CID169859984
|
Local ready
Direct docking supported
|